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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker
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Chapter 27: General and Local Anesthetic Agents

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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker | Registered Nurse (RN) School Study Aid

Chapter 27: General and Local Anesthetic Agents
5 Picmonics to Learn | 9 mins
Short-acting Benzodiazepines
Mnemonic
ATOM
Drug Names
Alprazolam
Triazolam
Oxazepam
Midazolam
Indications
Anesthesia Induction
Insomnia
Anxiety
Considerations
Half-life < 12 Hours
Dependence
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2 mins
IV Anesthetics
Barbiturates
Benzodiazepines
Respiratory Depression
Hypotension
Ketamine
NMDA Receptor Antagonist
Hallucinations
Opioids
Propofol
Potentiates GABA-A
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2 mins
Inhaled Anesthetics
Mechanism of Action
Unknown Mechanism
Inhaled Anesthetic Drugs
HEISMN Drug Name Acronym
Side Effects
Respiratory Depression
Myocardial Depression
Lower Metabolic Demand, Increased Cerebral Blood Flow
Hepatotoxicity (Halothane)
Nephrotoxicity (Methoxyflurane)
Seizure (Enflurane)
Malignant Hyperthermia
Expansion of Trapped Gas
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2 mins
Lidocaine
Mechanism
Blocks Na+ Channels
Indications
Ventricular Arrhythmia
Anesthetic
Side Effects
Paresthesias
Seizures
Respiratory Depression
Drowsiness
Consideration
Anesthetic Effects Extended with Epinephrine
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1 min
Local Anesthetic Overview
Indications
Minor Procedures
Epidurals
Mechanism of Action
Blocks Na+ Channels
State Dependent
Combined with Vasoconstrictors
Infected Tissue Requires Higher Dose
Drugs
Esters
Amides
Side Effects
Arrhythmias
Cardiotoxicity
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1 min

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