Lehne's Pharmacology for Nursing Care, 10th Ed., Burchum & Rosenthal, 2019 | Registered Nurse (RN) School Study Aid
Gastroesophageal Reflux Disease (GERD) Assessment
- Relaxed Lower Esophageal Sphincter
- Dyspepsia (Indigestion)
- Belching
- Nighttime Coughing
- Dysphagia
- Epigastric Pain
- Regurgitation
- Heartburn (Pyrosis)
- Globus
Peptic Ulcer Disease Assessment
- Helicobacter Pylori
- Increased Stomach Acid
- Abdominal Pain
- Heartburn (Pyrosis)
- Melena
- Weight Changes
- GI Distress
- Most Commonly in Duodenum
- Duodenal: Pain Relieved by Eating
- Gastric: Pain Caused by Eating
Peptic Ulcer Disease Interventions
- Combination Drug Therapy
- Two Antibiotics
- Proton Pump Inhibitor (PPI)
- Decrease Acid Secretion
- Avoid NSAIDs
- Diet and Lifestyle Changes
Ampicillin and Amoxicillin
- Aminopenicillin
- Broad Spectrum Penicillin
- Gram-Positive and Some Gram-Negative Infections
- Rash
- Diarrhea
- No Effect Against Staph Aureus
- Often combined with Beta Lactamase Inhibitor
- Allergic Reaction
Clopidogrel (Plavix)
- ADP Receptor Antagonist
- Prevent Platelet Aggregation
- Acute Coronary Syndrome (ACS)
- Prevention of Thrombotic Events
- Bleeding
- Thrombotic Thrombocytopenic Purpura (TTP)
- Pancytopenia
- Abdominal Pain
- Withhold Before Surgery
Cimetidine and Famotidine (H2 Receptor Blockers)
- -tidine Suffix
- H2 Receptor Blocker
- Suppress Gastric Acid Secretion
- Pneumonia
- Anti-androgen Effects
- CNS Changes
Omeprazole (Prilosec)
- "-prazole" Suffix
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Proton Pump Inhibitor (PPI)
- Inhibit H+/K+/ATPase
- Hip Fracture
- Pneumonia
Sucralfate (Carafate)
- Creates Protective Barrier
- GI Ulcers
- Constipation
- Require Acidic Environment
- Give on Empty Stomach
- Oral Suspension Available
- May Decrease Absorption of Other Meds
Barrett's Esophagus
- Metaplasia in Lower Esophagus
- Columnar Epithelium
- Gastroesophageal Reflux Disease (GERD)
- Esophagitis
- Esophageal Ulcers
- Increased Risk of Esophageal Adenocarcinoma