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Medical-Surgical Nursing, 10th Ed., Lewis, Dirksen, Heitkemper & Bucher/
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Medical-Surgical Nursing, 10th Ed., Lewis, Dirksen, Heitkemper & Bucher | Registered Nurse (RN) School Study Aid
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Fluoroquinolones
- End in "-floxacin"
- Mechanism of Action
- Bactericidal
- Indications
- Variety of Infections
- Side Effects
- GI Distress
- Photosensitivity
- Achilles Tendon Rupture
- Contraindications
- Pregnancy
- Children
- Myasthenia Gravis
- Considerations
- Avoid Milk Products or Antacids
- Slow IV Infusion
2 mins
Chloramphenicol (Chloromycetin)
- Mechanism
- Bacteriostatic
- Indications
- Gram Positive or Gram Negative Infections
- Side Effects
- Bone Marrow Suppression
- Aplastic Crisis
- Gray Syndrome
- Considerations
- Toxicity Limits Use
- Monitor Blood Counts
2 mins
Haloperidol (Haldol)
- Mechanism
- High Potency Antipsychotic
- Indications
- Migraine
- Schizophrenia
- Side Effects
- Extrapyramidal Symptoms
- Weight Gain
- QT Prolongation
- Restlessness
- Considerations
- Caution in Seizure Patients
- Neuroleptic Malignant Syndrome
2 mins
Hydrochlorothiazide HCTZ
- Mechanism of Action
- Inhibits Reabsorption NaCl and H2O
- Indications
- Edema
- Mild to Moderate Hypertension
- Side Effects
- Hypokalemia
- Hyponatremia
- Dehydration
- Hyperglycemia
- Gout
- Contraindications
- Sulfa Allergy
- Pregnancy and Breastfeeding
1 min
Chlorpromazine (Thorazine)
- Mechanism
- Low Potency Antipsychotic
- Indications
- Schizophrenia
- Hiccups
- Side Effects
- Sedation
- Weight Gain
- Orthostatic Hypotension
- Anticholinergic Effects
- QT Prolongation
- Neuroendocrine Effects
- Caution in Seizure Patients
- Corneal Deposits
2 mins
Chlorpropamide and Tolbutamide (Orinase) (1st Generation Sulfonylureas)
- Mechanisms
- 1st Generation Sulfonylureas
- Stimulate Release of Insulin
- Indications
- Type 2 Diabetes
- Side Effects
- Hypoglycemia
- Possible Cardiovascular Toxicity
- Weight Gain
- Considerations
- Exacerbated Hypoglycemia with Beta-blockers
- Avoid During Pregnancy and Breast Feeding
- Avoid Alcohol
2 mins
Glyburide and Glipizide (2nd Generation Sulfonylureas)
- Mechanisms
- 2nd Generation Sulfonylureas
- Blocks Potassium Channels in Beta Cells
- Stimulate Release of Insulin
- Indications
- Type 2 Diabetes
- Side Effects
- Hypoglycemia
- Considerations
- More Potent
- Beta Blockers Reduce Effects
- Avoid Alcohol
- Avoid Breastfeeding
2 mins
Griseofulvin
- Mechanism
- Disrupts Microtubules in Mitosis
- Indications
- Antifungal for Superficial Infections
- Tinea and Ringworm
- Side Effects
- Teratogen
- P450 Inducer
- Confusion
- Headache
2 mins
Tetracyclines Overview
- End in "-cycline"
- Mechanism of Action
- Bacteriostatic
- Indications
- Infectious Diseases
- Acne
- Periodontal Disease
- Nursing Considerations
- Avoid Milk, Antacids, Iron
- Sunlight Protection
1 min
Tetracyclines Side Effects
- Side Effects
- Superinfection
- Clostridioides difficile
- Discoloration of Teeth
- Bone Deformities
- Photosensitivity
- Contraindications
- Children Under 8
- Pregnancy
1 min
Vitamin C (Ascorbic Acid)
- Mechanism
- Antioxidant
- Collagen Formation
- Steroid Synthesis
- Indications
- Dietary Deficiency
- Scurvy
- Side Effects
- GI Distress
- Considerations
- Citrus Fruits
- May Improve Healing
2 mins
Vitamin B3 - Niacin (Nicotinic Acid)
- Mechanism
- Decreases Triglycerides
- Decreases LDL
- Increases HDL
- Indications
- Dyslipidemia
- Pellagra
- Diarrhea
- Dermatitis
- Dementia
- Side Effects
- Flushing
- GI Distress
- Hepatotoxicity
2 mins
Vitamin K1 (Phytonadione)
- Mechanism
- Synthesizes Clotting Factors II, VII, IX, X
- Indications
- Hypoprothrombinemia
- Newborn Prophylaxis
- Bleeding from Warfarin Overdose
- Side Effects
- Shock
- Kernicterus
- Cardiac Arrest
- Considerations
- Bile Salts required for Intestinal Absorption
- Increased Risks with IV Administration
2 mins
Vitamin A (Retinol)
- Mechanism
- Maintains Mucous Membranes
- Eyes and Skin
- Indications
- Dietary Deficiency
- Skin Disorders
- Side Effects
- Hepatosplenomegaly
- Jaundice
- Increased ICP
- Vomiting
- Considerations
- Teratogen
- Animal Food Products
- Dark Green and Orange Fruits/Vegetables
2 mins
Cholecalciferol (Vitamin D3)
- Mechanism
- Vitamin D3
- Indications
- Dietary Supplement
- Vitamin D Deficiency
- Side Effects
- Fatigue
- Constipation
- Hypercalcemia
- Kidney Stones
- Considerations
- More Effective Than Ergocalciferol
- Hypervitaminosis D
2 mins
Vitamin B6 (Pyridoxine)
- Mechanism
- Amino Acid and Protein Metabolism
- Heme Synthesis
- Neurotransmitters
- Indications
- Adjunct to Isoniazid
- Dietary Deficiency
- Premenstrual Syndrome (PMS)
- Side Effects
- Ataxia
- Peripheral Neuropathy
- Contraindications
- Levodopa
- Considerations
- Cereals and Meats
3 mins
ABCDEs of Melanoma
- Asymmetry
- Border
- Color
- Diameter
- Evolving
1 min
Cephalosporins
- Starts with "Cef-"
- Mechanism of Action
- Bactericidal
- Indications
- Gram-Positive and Gram-Negative Infections
- Side Effects
- Allergic Reactions
- Thrombophlebitis
- Bleeding
- Contraindications
- Renal Impairment
- Considerations
- Avoid IV Calcium with Ceftriaxone
- No Alcohol
2 mins
Vancomycin
- Mechanism of Action
- Inhibits Bacterial Cell Wall Synthesis
- Indications
- Serious Gram-Positive Infections
- Side Effects
- Nephrotoxicity
- Ototoxicity
- Red Man Syndrome
- Thrombophlebitis
- Nursing Considerations
- Culture Samples First
- Infuse IV Over 60 Minutes
- Take Around the Clock
2 mins
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
Herpes Zoster (Shingles)
- Cause/Mechanism
- Varicella-Zoster Virus
- Assessment
- Linear, Unilateral Rash Along a Dermatome
- Pruritus
- Postherpetic Neuralgia
- Interventions
- Acyclovir
- Analgesics
- Gabapentin
- Considerations
- Contagious Vesicles
- Shingrix
3 mins
Gabapentin
- Primary Indication
- Seizure Treatment
- Secondary Indications
- Peripheral Neuropathy
- Postherpetic Neuralgia
- Bipolar Disorder
- Migraine Prophylaxis
- Characteristics
- Inhibits Voltage-Gated Ca2+ channels
- Designed as a GABA Analog
- Side Effects
- Ataxia
- Sedation
2 mins
Genital Herpes
- Mechanism
- Herpes Simplex Virus 1 and 2 (HSV)
- Assessment
- May Be Asymptomatic
- Oral or Genital Lesions
- Vesicles in Clusters
- Pain
- Flu-like Symptoms
- Antiviral Medications
- Acyclovir
- Valacyclovir
- Famciclovir
- Considerations
- Infectious During Recurrences
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
- Mechanism
- Topical Antimicrobial
- Indications
- Burns
- Open Wound Care
- Side Effects
- Mafenide
- Pain
- Acidosis
- Considerations
- Administer Analgesic Prior to Wound Care
1 min
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