Medical-Surgical Nursing, 10th Ed., Lewis, Dirksen, Heitkemper & Bucher | Registered Nurse (RN) School Study Aid
Urinary Excretory Anatomy
- Renal Medulla
- Renal Cortex
- Nephron
- Bowman's Capsule
- Glomerulus
- Proximal Tubule
- Loop of Henle
- Distal Tubule
- Collecting Duct
- Ureter
- Urinary Bladder
- Urethra
Renal Corpuscle
- Arterioles
- Glomerulus
- Capillaries
- Fenestrations
- Plasma Solutes and Other Small Molecules Become Ultrafiltrate
- Bowman's Capsule Encapsulates Glomerulus
Proximal Tubule
- Na+ Reabsorbed Via Active Transport
- Water Follows Na+
- Most Of Glucose Reabsorbed
- Most Of Amino Acids Reabsorbed
- Bicarbonate Exchanged For H+
- Drugs and Toxins Excreted
- Filtrate Osmolarity Same As Plasma
- Leads To Loop Of Henle
Loop of Henle
- Descending Limb
- Water Follows Na+
- Medullary Hypertonicity
- Increased Water Reabsorption
- Vasa Recta
- Na+ Reabsorbed Via Active Transport
- Ascending Limb
- Reabsorbs Na+, K+, Cl-
- Decreased Concentration of Filtrate
- Impermeable to Water
- Distal Tubule
Distal Tubule
- Hormonally Regulated
- Aldosterone Causes Na+ Reabsorption
- Na+ Reabsorbed Via Active Transport
- Water follows Na+
- Early Distal Tubule is Impermeable to Water
- Parathyroid Hormone Causes Ca2+ Reabsorption
- Leads to Collecting Duct
Collecting Duct
- Na+ Reabsorption
- Vasopressin Causes Water reabsorption
- Concentrates Filtrate
Erythropoietin
- Stimulates RBC Production
- Chronic Renal Failure
- Anemia
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
Loop Diuretics
- Thick Ascending Limb of Loop of Henle
- Inhibits Na+-K+-2Cl-
- Sulfa Drug
- Furosemide
- Lasix
- Ototoxicity from Rapid Injection
- Gout
- Dehydration
- Hypocalcemia
- Hypokalemia
- Orthostatic Hypotension
Amphotericin B
- Systemic Mycosis
- Fungal Meningitis
- Last Resort for Protozoan infections
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
Vancomycin Side Effects & Toxicity
- Thrombophlebitis
- Nephrotoxicity
- Ototoxicity
- Diffuse Flushing Called Red Man Syndrome
- Prevent with Antihistamine
- Prevent with Slow Infusion
Methotrexate
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
NSAIDs
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
Lithium
- Mood Stabilizer
- Unknown Mechanism
- Bipolar Disorder
- Nephrogenic Diabetes Insipidus
- Hypothyroidism
- Tremor
- Heart Block
- Pregnancy
- Monitor Plasma Levels
Cephalosporins
- Starts with "Cef-"
- Bactericidal
- Gram-Positive and Gram-Negative Infections
- Allergic Reactions
- Thrombophlebitis
- Bleeding
- Renal Impairment
- Avoid IV Calcium with Ceftriaxone
- No Alcohol
Cyclosporine (Sandimmune) Side Effects
- Nephrotoxicity
- Hepatotoxicity
- Infection
- Hypertension
- Hirsutism
- Tremor
- Hyperkalemia
- Hypomagnesemia
- Gingival Hyperplasia
Vancomycin
- Inhibits Bacterial Cell Wall Synthesis
- Serious Gram-Positive Infections
- Nephrotoxicity
- Ototoxicity
- Red Man Syndrome
- Thrombophlebitis
- Culture Samples First
- Infuse IV Over 60 Minutes
- Take Around the Clock
Cisplatin (Platinol)
- Alkylating Agent
- Cross-Links DNA
- Testicular Cancer
- Ovarian Cancer
- Nausea and Vomiting
- Myelosuppression
- Nephrotoxicity
- Ototoxicity
- Peripheral Neuropathy
- Antiemetics Before Administration
- Aggressive Hydration
Aminoglycoside Side Effects
- Ototoxicity
- Nephrotoxicity
- Respiratory Paralysis
- Pregnancy
- Peak and Trough
- Never Mix with Penicillin in Same IV
Sulfonamides
- Bacteriostatic
- Urinary Tract Infection
- Crystalluria
- Photosensitivity
- Hemolytic Anemia
- Kernicterus
- Rash
- Sulfa Allergy
- Encourage Fluids
Creatinine Lab Values
- Measures Renal Function
- 0.6 - 1.3 mg/dL
Phosphate (PO43-) Lab Value
BUN (Blood Urea Nitrogen) Lab Values
Pyelogram
- Visualizes Urinary Tract
- Diagnose Urinary Disorders
- Bowel Prep (Enema)
- IV Contrast Media
- X-Ray (Radiopaque)
- Increase Fluid Intake
- Iodine Allergy
- Decreased Renal Function
Magnetic Resonance Imaging (MRI)
- Internal Body Images
- Detects Variations of Soft Tissues
- No Metal Objects
- No Pacemakers
- Contrast is Non-Iodine
- Safe During Pregnancy
- Long Procedure
- Antianxiety Medications
pH - Blood and Urine Lab Value
- Blood
- 7.35 - 7.45
- Urine
- 4.0 - 8.0
Urine Specific Gravity Lab Value