Medical-Surgical Nursing, 10th Ed., Lewis, Dirksen, Heitkemper & Bucher | Registered Nurse (RN) School Study Aid
Osteoarthritis
- Articular Cartilage Destruction
- Biomechanical Stress
- Aging
- Asymmetric
- Pain Decreases with Rest
- Morning Stiffness Under 30 Minutes
- Crepitus
- DIP and PIP Joints
- Lifestyle Changes
- Acetaminophen or NSAIDs
Osteoarthritis Assessment
- Aging
- Articular Cartilage Destruction
- Biomechanical Stress
- Asymmetric
- Pain Decreases with Rest
- Morning Stiffness under 30 Minutes
- Crepitus
- DIP and PIP Joints
Osteoarthritis Interventions
- Balance Rest and Activity
- Therapeutic Exercise
- Heat and Cold Applications
- Intra-articular Injection
- NSAIDs
- Reconstructive Joint Surgery
Methotrexate
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
Prednisone (Glucocorticoids)
- Glucocorticoid
- Inflammatory Conditions
- Organ Transplant Rejection
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Adrenal Insufficiency
- Taper Gradually
Celecoxib
- Rheumatoid Arthritis
- Osteoarthritis
- Pain
- NSAID
- Selectively Inhibits COX-2
- Sulfa Allergy
- Increased Risk of Thrombosis
- GI Bleed
- Pregnancy > 30 Weeks
Aspirin (Acetylsalicylic Acid)
- Inhibits Platelet Aggregation
- NSAID
- Thrombotic Event Prevention
- General Pain
- Inflammatory Conditions
- Fever
- Pancytopenia
- GI Ulcers
- Bleeding
- Withhold Before Surgery 7-10 Days
- Reye's Syndrome
Ibuprofen (Advil, Motrin)
- NSAID
- COX Inhibitor
- General Pain
- Fever
- Inflammatory Conditions
- GI Ulcers
- Nephrotoxicity
- Rash
- Avoid with Alcohol
- Risk of Thrombotic Event
NSAIDs
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
Rheumatoid Arthritis Assessment
- Destruction of Connective Tissue and Synovial Membrane
- Inflammation of Joints
- Morning Stiffness
- Nodules
- Joint Deformities
Rheumatoid Arthritis Interventions
- Heat and Cold Applications
- Therapeutic Exercise
- Balance Rest and Activity
- NSAIDs
- DMARDs
- Glucocorticoids
- PT/OT
- Reconstructive Joint Surgery
Gout Disease
- Acute Inflammatory Monoarthritis
- Primarily in Males
- Precipitation of Monosodium Urate Crystals
- Underexcretion of Uric Acid
- Overproduction of Uric Acid
- Negatively Birefringent, Needle-Shaped
- Swollen, Red, Painful Joint
- Asymmetric Joint Distribution
- Podagra
- Tophus
- After Large Meal or Alcohol
Gout Treatment
- NSAIDs
- Glucocorticoids
- Colchicine
- Impairs Leukocyte Chemotaxis
- Inhibit Xanthine Oxidase
- Allopurinol
- Febuxostat
- Inhibit Reabsorption of Uric Acid
- Probenecid
Pseudogout
- > 50 Years Old
- Arthritis of Large Joints (Classically the Knee)
- Calcium Pyrophosphate Crystals
- Positively Birefringent
- Chondrocalcinosis (On X-ray)
- NSAIDs
- Colchicine
- Steroids
Ampicillin and Amoxicillin
- Aminopenicillin
- Broad Spectrum Penicillin
- Gram-Positive and Some Gram-Negative Infections
- Rash
- Diarrhea
- No Effect Against Staph Aureus
- Often combined with Beta Lactamase Inhibitor
- Allergic Reaction
Lyme Disease
- Transmitted by Ticks (Vector-borne)
- Flu-like Symptoms
- Bulls Eye Rash (Erythema Migrans)
- Joint Pain and Stiffness
- Facial Paralysis
- Antibiotics
- Prevention
Systemic Lupus Erythematosus (SLE) Assessment
- Multisystem Inflammatory Disorder
- Malar Rash
- Discoid Rash
- Arrhythmias
- Arthritis
- Hemolytic Anemia
- Seizures
- Glomerulonephritis
- Periods of Exacerbation and Remission
- Diagnosed by ANA (Anti-nuclear antibody assay)
Tacrolimus (Prograf) Overview
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Transplant Rejection
- Atopic Dermatitis
- Increased Lymphoma Risk
- Avoid Grapefruit Juice
Systemic Lupus Erythematosus (SLE) Interventions
- Avoid Sunlight
- Glucocorticoids
- Methotrexate
- NSAIDs
- Hydroxychloroquine
- Azathioprine
- Monitor for Renal Failure (ARF)
- Manage Pain
Tricyclic Antidepressants (TCAs) Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
Trazodone
- Insomnia
- Depression
- Inhibit Serotonin Reuptake
- Alpha-1 Blocker
- Histamine (H1) Blocker
- Sedation
- Orthostatic Hypotension
- Dry Mouth
- Priapism
- Arrhythmias
Diazepam (Valium)
- Anxiety
- Seizures and Status Epilepticus
- Muscle Spasms
- Alcohol Withdrawal
- Dizziness/Vision Changes
- Confusion/Amnesia
- Urinary Incontinence
- Behavioral Changes
- Respiratory Depression
- Flumazenil (Romazicon)
- Fall Precaution
- Do Not Stop Abruptly
Pregabalin (Lyrica)
- GABA Analog
- Seizures
- Neuropathic Pain
- Fibromyalgia
- Headache
- Dizziness
- Somnolence (Fatigue)
- Weight Gain
- Angioedema
- Rhabdomyolysis
- Dependence
Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Depression
- Anxiety
- Selective Serotonin Reuptake Inhibitors
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine