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Understanding Pathophysiology, 6th Ed., Huether, McCance, Brashers, & Rote/
6 - Innate Immunity: Inflammation and Wound HealingAce Your Understanding Pathophysiology, 6th Ed., Huether, McCance, Brashers, & Rote Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Registered Nurse (RN) Students
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Understanding Pathophysiology, 6th Ed., Huether, McCance, Brashers, & Rote | Registered Nurse (RN) School Study Aid
Innate Immunity Barriers
- Skin Protects Against Pathogens
- Normal Flora Outcompete Pathogens
- Lysozyme in Saliva, Tears, and Mucus
- Mucous Traps Pathogens
- Cilia Remove Mucus
- Acid and Digestive Enzymes in the Stomach Kill Pathogens
2 mins
Innate Immunity Cellular Response
- Characteristics
- Natural Killer Lymphocytes Attack Abnormal Cells
- Neutrophils in Blood
- Infected Cells Release Interferon
- Complement Proteins Lyse Pathogens/Infected Cells
- Dendritic Cells in Tissue
- Macrophages in Tissue
2 mins
Inflammatory Response
- Pathogens Infect Tissue
- Mast Cells Release Histamine
- Histamine Dilates and Increases Capillary Permeability
- Macrophages Engulf Pathogens
- Macrophage Signals Cells With Cytokines
- Responding Neutrophils Cross Capillary Wall
- B And T Lymphocytes Arrive At Injury Site
2 mins
Clotting Overview
- Characteristics
- Endothelial Cells are Damaged
- Platelets Respond to Exposed Collagen and Stick
- Platelets Release Recruiting Factors
- More Platelets are Attracted
- Soluble Fibrinogen Turns to Insoluble Fibrin
- Fibrin Seals the Clot
- Clot Dissolves
- Liver Produces Clotting Factors
2 mins
Platelet Lab Value
- 150,000-400,000 Micro L
40 secs
Wound Drainage Types and Devices
- Drainage Types
- Serous
- Serosanguineous
- Sanguineous
- Purulent
- Drainage Devices
- T-tube
- Penrose
- Jackson-Pratt (JP)
- Hemovac
- Considerations
- Record Drainage Amounts
- Check Device Function
2 mins
Fever
- Flushed skin, warm to touch
- Chills
- Sweating
- Change in LOC
- Provide adequate fluids
- Monitor Electrolytes and Fluid
- Monitor vital signs, esp temperature
- Remove excess clothing and blankets
- Sponge bath with tepid water
2 mins
Types of Wound Healing
- Types of Wounds
- Acute
- Chronic
- Healing Process
- Primary Intention
- Approximated Edges
- Secondary Intention
- Edges Not Approximated
- Tertiary Intention
- Delayed Closure due to Infection and Necrosis
2 mins
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