Hypothalamus
- Anterior Pituitary Stimulated Through the Hypophyseal Portal
- GHRH
- GnRH
- TRH
- PIF
- CRF Released During Stress
- Posterior Pituitary Stimulated Through Neural Control
Anterior Pituitary
- Hypothalamic Control
- FLAT PeG Mnemonic
- Follicle-Stimulating Hormone (FSH)
- Lutenizing Hormone (LH)
- Adrenocorticotropic Hormone (ACTH)
- Thyroid-Stimulating Hormone (TSH)
- Prolactin (PRL)
- Growth Hormone (GH)
Posterior Pituitary
- Neuroendocrine Reflex Stimulation (By Hypothalamus)
- Vasopressin
- Increased Water Retention (In Kidneys)
- Oxytocin
- Increased Uterine Contraction
- Mammary Glands Contraction
Adrenal Gland (Basic)
- Adrenal Cortex
- RAAS Stimulates Aldosterone
- CRF (CRH) acts on Anterior Pituitary Gland to Release ACTH
- Cortisol Released
- Androgens Released
- Adrenal Medulla
- Epinephrine & Norepinephrine
Adrenal Gland (Advanced)
- Adrenal Cortex
- Zona Glomerulosa
- Aldosterone
- Zona Fasciculata
- Cortisol
- Zona Reticularis
- Androgens
- Adrenal Medulla
- Chromaffin Cells
- Epinephrine & Norepinephrine
Electrical Synapse
- Cardiac and Smooth Muscle Location
- Fast Transmission
- Bidirectional
- Presynaptic Na+ Floods Through Gap Junction
- Na+ Influx Initiates Postsynaptic Action Potential
Chemical Synapse
- Voltage-Gated Calcium Channels Open
- Ca2+ Influx
- Vesicle-Membrane Fusion
- Exocytosis of Neurotransmitter
- Neurotransmitter Binds Post-Synaptic Receptors
- Neurotransmitter Breakdown
- Neurotransmitter Reuptake
Benzodiazepines Overview
- First Line for Status Epilepticus
- Anesthesia Induction
- Anxiety
- Eclampsia
- Detoxification
- '-zepam' and '-zolam" Suffix
- Increase Frequency of Cl- Channel Opening
- Decrease REM Sleep
- CNS Depression
- Dependence
- Flumazenil for Overdose
Zolpidem (Ambien)
- Hypnotic
- Insomnia
- Daytime Drowsiness
- Bizarre Sleep Behaviors
- Sleep Driving
- Angioedema
- Short Term Administration
- Take Immediately Before Bedtime
Tricyclic Antidepressants (TCAs)
- Inhibits Reuptake of Norepinephrine and Serotonin
- Depression
- Bipolar Disorder
- Fibromyalgia
- Sedation
- Orthostatic Hypotension
- Anticholinergic Effects
- Cardiac Toxicity
- Delayed Effect
- Do Not Stop Abruptly
Tricyclic Antidepressants (TCAs) Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
Buspirone (Buspar)
- Increases Serotonin
- Anxiety
- Dizziness
- Insomnia
- Delayed Effect
- Safer with Alcohol than Other Anxiolytics
- Low Side Effect Profile
- Low Abuse Potential
Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Depression
- Anxiety
- Selective Serotonin Reuptake Inhibitors
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
Fluoxetine (Prozac)
- Inhibits Reuptake of Serotonin
- Depression
- Sexual Dysfunction
- CNS Stimulation
- Weight Changes
- Serotonin Syndrome
- No MAO-Is
- No Anticoagulants / Antiplatelets
- Suicide Risk
- Delayed Onset of Action
Trazodone
- Insomnia
- Depression
- Inhibit Serotonin Reuptake
- Alpha-1 Blocker
- Histamine (H1) Blocker
- Sedation
- Orthostatic Hypotension
- Dry Mouth
- Priapism
- Arrhythmias
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Depression
- Diabetic Peripheral Neuropathy
- Duloxetine
- Panic and Anxiety
- Venlafaxine
- Inhibits Reuptake of Serotonin and NE
- Hypertension
- Insomnia
- Nausea and Vomiting
- Decreased Libido
Monoamine Oxidase Inhibitors (MAO-Is)
- Atypical Depression
- Increase Levels of Amine Neurotransmitters
- "Takes Pride In Shanghai"
- Tranylcypromine
- Phenelzine
- Isocarboxazid
- Selegiline
Lithium
- Mood Stabilizer
- Unknown Mechanism
- Bipolar Disorder
- Nephrogenic Diabetes Insipidus
- Hypothyroidism
- Tremor
- Heart Block
- Pregnancy
- Monitor Plasma Levels
Valproic Acid (Depakote)
- Blocks Na+ Channels
- Increases GABA Concentration
- Tonic-clonic Seizures
- Bipolar Disorder
- Migraine Prophylaxis
- Hepatotoxicity
- Blood Dyscrasias
- GI Distress
- Tremor
- Pancreatitis
Carbamazepine (Tegretol)
- Inactivates Na+ Channels
- Seizures
- Bipolar Disorder
- Trigeminal Neuralgia
- Nystagmus
- Ataxia
- Hepatotoxicity
- Blood Dyscrasias
- Water Retention
- Stevens-Johnson Syndrome
- Avoid Grapefruit Juice
Lamotrigine (Lamictal)
- Blocks Na+ Channels
- Seizures
- Bipolar Disorder
- Diplopia
- Stevens-Johnson Syndrome
- Headache
- Aseptic Meningitis
- Nausea and Vomiting
- Screen for Suicide Risk
Antipsychotics Overview
- Typical
- Atypical
- Blocks D2 Receptor
- 2nd Generation Blocks the 5-HT 2 Receptor
- Psychosis
- Delirium
- Bipolar Disorder
- Tourette’s Syndrome
- Hyperprolactinemia
- Extrapyramidal Symptoms
- Tardive Dyskinesia
- Neuroleptic Malignant Syndrome
Atypical Antipsychotics
- Schizophrenia
- Unknown Mechanism
- Seizures
- Prolonged QT Interval
- Agranulocytosis
- Weight Gain
- Fewer Extrapyramidal Side Effects
- Fewer Anticholinergic Side Effects
Clozapine (Clozaril)
- Atypical Antipsychotic
- Schizophrenia
- Levodopa-Induced Psychosis
- Weight Gain
- Hypersalivation (Sialorrhea)
- Myocarditis
- Agranulocytosis
- Sedation
- Orthostatic Hypotension
- Constipation (Risk of Bowel Ileus)
- Weekly Lab Tests
Risperidone (Risperdal)
- Atypical Antipsychotic
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Intramuscular Long Acting (Depot) Form
Aripiprazole (Abilify)
- 2nd Generation Atypical Antipsychotic
- Schizophrenia
- Bipolar Disorder
- Depression
- Headache
- Dizziness
- Nausea and Vomiting
- Insomnia
- Anxiety
- Low Risk of Extrapyramidal Symptoms
- Lowest Risk of Weight Gain
Attention-Deficit Hyperactivity Disorder (ADHD) Assessment
- Inattention
- Incomplete Tasks
- Easily Distracted
- Hyperactivity
- Impulsiveness
- Disruptive
- Two Areas of Life
- Onset by Age 12
- Symptoms > 6 Months
Attention-Deficit Hyperactivity Disorder (ADHD) Interventions
- CNS Stimulants
- Amphetamine
- Methylphenidate
- Bupropion (Wellbutrin)
- Atomoxetine (Strattera)
- Guanfacine (Intuniv)
- Manage Disruptive Behavior
- Provide Simple Instructions
Alzheimer's Disease Assessment (Early Symptoms)
- Advanced Age
- Poor Judgment and Decision-Making
- Difficulty Having a Conversation
- Inability to Manage a Budget
- Losing Track of the Date or Season
- Misplacing Things
Alzheimer's Disease Assessment (Late Symptoms)
- Memory Impairment
- Wandering Behavior
- Confabulation
- Perseveration
- Lack of Abstract Thinking
- Severe Cognitive Decline
Alzheimer's Disease Interventions
- PET Scan and CT
- Mini-Mental State Examination
- Drug Therapy
- Safe Environment
- Moderate Exercise
- Behavioral Modification
- Assistance with Functional Independence
- Assistance and Support for Caregiver