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Cardiovascular System | Pharmacist (Pharm.D) School Study Aid
Class I Antiarrhythmics (Na+ Channel Blockers) Overview
- Indications
- Arrhythmias
- Local Anesthesia
- Mechanism of Action
- Block or Slow Conduction
- Block Na+ Channels
- Raise Threshold
- State Dependent
- Contraindication
- Hyperkalemia
1 min
Class IA Antiarrhythmics (Na+ Channel Blockers)
- Indications
- Arrhythmias
- Mechanism of Action
- Increase AP, ERP, and QT interval.
- Drugs
- Disopyramide
- Procainamide
- Drug-induced Lupus
- Quinidine
- Cinchonism
- Shared Side Effects
- Thrombocytopenia
- Torsades de Pointes
1 min
Class IB Antiarrhythmics (Na+ Channel Blockers)
- Indications
- Arrhythmias
- After Myocardial Infarction
- Mechanism of Action
- Affect Ischemic Tissue
- Decrease AP duration
- Drugs
- Mexiletine
- GI Upset
- Lidocaine
- CNS Depression
- Tocainide
- Phenytoin
- Hirsutism
2 mins
Class IC Antiarrhythmics (Na+ Channel Blockers)
- Indications
- Used as Last Resort
- V-Tach
- Mechanism of Action
- No Effect on AP Duration
- Drugs
- Propafenone
- Flecainide
- Contraindications
- Post-Myocardial Infarction
56 secs
Class III Antiarrhythmics (K+ Channel Blockers)
- Indications
- Arrhythmias
- Mechanism of Action
- Increase AP Duration, ERP, and QT Interval
- Drug Names
- Amiodarone
- Check Function Tests
- Dirty Drug
- Ibutilide
- Dofetilide
- Sotalol
- Beta-Blocker
2 mins
Class IV Antiarrhythmics (Ca2+ Channel Blockers)
- Indications
- SVT
- Subarachnoid Hemorrhage
- Mechanism of Action
- Decrease Conduction Velocity
- Increase PR Interval and ERP
- Drugs
- Verapamil
- Diltiazem
- Nimodipine
- Side Effects
- Cardiovascular
- Constipation
2 mins
Adenosine (Adenocard)
- Mechanism
- Slows AV Conduction
- Indications
- Supraventricular Tachycardia (Paroxysmal)
- Side Effects
- Bradycardia
- Flushing
- Dyspnea
- Considerations
- Rapid IV Push
- Caffeine and Theophylline Decrease Effectiveness
- Dipyridamole May Intensify Effects
2 mins
Lidocaine
- Mechanism
- Blocks Na+ Channels
- Indications
- Ventricular Arrhythmia
- Anesthetic
- Side Effects
- Paresthesias
- Seizures
- Respiratory Depression
- Drowsiness
- Consideration
- Anesthetic Effects Extended with Epinephrine
1 min
Magnesium Sulfate
- Mechanism
- Muscle Relaxant
- Indications
- Preterm Labor Contractions
- Preeclampsia
- Side Effects
- Warm Feeling
- Hypotension
- Decreased Deep Tendon Reflexes (DTRS)
- Decreased Respiratory Rate
- Decreased Urine Output
- Paralytic Ileus
- Antidote
- Calcium Gluconate
2 mins
Calcium Channel Blockers (Verapamil and Diltiazem)
- Mechanism of Action
- Slows AV Conduction
- Indications
- Angina Pectoris
- Arrhythmias
- Essential Hypertension
- Side Effects
- Bradycardia
- Hypotension
- Constipation
- Peripheral Edema
- Gingival Hyperplasia
- Nursing Consideration
- Medication Education
2 mins
Amiodarone
- Mechanisms
- Class III Antiarrhythmic (K+ Channel Blocker)
- Decreases SA and AV Node Conduction
- Inhibits Cytochrome P450
- Indications
- Supraventricular Tachycardia with Heart Failure
- Ventricular Tachycardia
- Side Effects
- Hepatotoxicity
- Pulmonary Fibrosis
- Bradycardia
- Heart Block
- Thyroid Disorders
- Blue/Gray Skin Deposits
- Corneal Deposits
3 mins
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