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Pharmacist (Pharm.D)
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Microbiology
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Gram Negative Bacilli

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Microbiology | Pharmacist (Pharm.D) School Study Aid

Gram Negative Bacilli
22 Picmonics to Learn | 44 mins
Yersinia Pestis (Black Plague)
Characteristics
Gram-Negative
Bacilli
Oxidase-Negative
Non-lactose Fermenting
Prairie Dogs
Fleas
Polysaccharide Capsule
Vw Antigen
F1 Antigen
Inhibits Macrophages
Southwest Region
Signs and Symptoms
Lymphadenopathy
Pneumonia
Black Cutaneous Hemorrhagic Lesions
Buboes
Diagnosis
Bipolar Giemsa Staining
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3 mins
Yersinia Enterocolitica
Characteristics
Gram-Negative
Bacilli
Non-lactose Fermenting
Non-H2S Producing
Oxidase-Negative
Day Care Centers
Pork
Raw Milk
Pet (Puppy) Feces
Signs and Symptoms
Bloody Diarrhea
Mesenteric Adenitis
Granulomatous Microabscess in Mesenteric Lymph Nodes
Pseudoappendicitis (Mimics)
Reactive Arthritis
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2 mins
Shigella
Characteristics
Gram-Negative
Bacilli
Non Lactose Fermenting
White on Macconkey Agar
Oxidase Negative
Non H2S Producing
Day Care Centers
High Virulence
Replicates Intracellularly
Actin Rocket
Signs and Symptoms
Bloody Diarrhea
Shiga Toxin
Inhibits 60S Ribosome
Hemolytic Uremic Syndrome (HUS)
Hemolytic Anemia
Thrombocytopenia
Kidney Failure
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3 mins
Salmonella Overview
Pathophysiology
Gram-Negative Rod
Oxidase Negative
Non Lactose Fermenter
White on Macconkey Agar
H2S Producing
Flagella
Invades GI Tract
Peyer's Patches
Considerations
Osteomyelitis in Sickle Cell Patients
Reactive Arthritis
Antibiotics Prolong Fecal Excretion
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3 mins
Salmonella Enterica Spp.
Characteristics
Animal and Human Reservoir
Poultry and Eggs
Turtles
PMN Immune Response
Symptoms
Gastroenteritis
Diarrhea
Possibly Bloody
Treatments
No Antibiotics
No Vaccine Available
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2 mins
Salmonella Typhi
Characteristics
Colonizes Gallbladder
Monocytic Immune Response
Symptoms
Typhoid Fever
Abdominal Pain
Rose Spots on Abdomen
Constipation Followed by Diarrhea
Treatments
Ceftriaxone
Fluoroquinolones
Considerations
Oral Vaccine - Live
IM Vaccine - Capsular Polysaccharide
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2 mins
Klebsiella Characteristics
Characteristics
Gram-Negative
Bacilli
Oxidase-Negative
Intestinal Flora
Antiphagocytic Virulence Factor
Polysaccharide Capsule
Positive Quellung Reaction
Mucoid Colonies
Urease-Positive
Fast Lactose Fermenter
Pink on MacConkey Agar
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2 mins
Klebsiella Disease
Signs and Symptoms
Aspiration Pneumonia
Alcoholics
Diabetics
Red Currant Jelly Sputum
Lung Abscess
Nosocomial Urinary Tract Infection
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2 mins
E. coli Overview
Characteristics
Gram-Negative
Bacillus
Purple Colony with Metallic Green Sheen
Lactose-Fermenting
Pink on MacConkey Agar
Disease
Diarrhea
Lipid A Septic Shock
P Pili Pyelonephritis and Cystitis
K Capsule Neonatal Meningitis
K Capsule Pneumonia
H Antigen Flagella
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2 mins
Enterohemorrhagic E. Coli (EHEC)
Characteristics
O157:H7
Non-Sorbitol Fermenting
Hamburger Meat
Produces Shiga-like Toxin
Gram-negative
Lysogeny
Inactivates 60S Ribosome
Disease
Bloody Diarrhea
Hemolytic Uremic Syndrome (HUS)
Hemolytic Anemia
Acute Renal Failure
Thrombocytopenia
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2 mins
Proteus Mirabilis
Characteristics
Gram-Negative
Bacillus
Oxidase Negative
Urease-Positive
Swarming Motility
Non-lactose Fermenting
Symptoms
Urinary Tract Infection
Struvite Crystals
Staghorn Kidney Stones
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2 mins
Helicobacter Pylori
Characteristics
Gram-Negative
Bacilli
Curved
Polar Flagellum
Catalase-Positive
Oxidase-Positive
Disease
Gastric and Duodenal Ulcers
Ammonia
Neutral Environment
Gastric Adenocarcinoma
MALT lymphoma
Diagnosis
Serology IgG antibody
Stool Antigen
Urease Positive Breath Test
Biopsy
Treatment
2 ABX and PPI
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2 mins
Helicobacter pylori Associations
Gastritis
Peptic Ulcer Disease
Stomach Cancer
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50 secs
Legionella Characteristics
Characteristics
Bacillus
Poor Gram Stain
Charcoal Yeast with Iron and Cysteine
Silver Stain
Water Sources
Smokers and Heavy Drinkers
Detect Antigen in Urine
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2 mins
Legionella Disease
Signs and Symptoms
High Fever
Diarrhea
Increased Liver Enzymes
Hyponatremia
Type IV Renal Tubular Acidosis
Severe Atypical Pneumonia
Pontiac Fever
Treatment
Fluoroquinolones
Macrolides
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2 mins
Campylobacter jejuni
Characteristics
Gram-Negative
Bacillus
Flagella
Curved
Corkscrew Appearance
Oxidase-Positive
Grows Well at 42 Degrees
Undercooked Meat
Unpasteurized Milk
Animals with Diarrhea
Signs and Symptoms
Bloody Diarrhea
Guillain-Barre syndrome
Reactive Arthritis
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3 mins
Pseudomonas Aeruginosa Characteristics
Characteristics
Gram-Negative
Bacillus
Aerobic
Pyocyanin Pigment
Blue-green Pigment
Grape like odor
Non-lactose Fermenting
Polysaccharide Capsule
Catalase-Positive
Oxidase-Positive
Inactivates Elongation Factor 2
Exotoxin A
Endotoxin
Water sources
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3 mins
Pseudomonas Aeruginosa Disease
Signs and Symptoms
Pneumonia
Cystic Fibrosis
Burn Wounds
Hot tub folliculitis
Urinary Tract Infections
Osteomyelitis associated with IV drug use
Osteomyelitis from Shoe Puncture Wound
Diabetic Osteomyelitis
Corneal Infections in contact lens users
Endocarditis
Ecthyma Gangrenosum
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3 mins
Vibrio Cholera Characteristics
Gram-Negative
Bacilli
Glucose Fermenting
Non-lactose Fermenting
Oxidase Positive
Comma Shaped
Thrives in Alkaline Environment
Crustaceans
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1 min
Vibrio Cholera Disease
ADP Ribosylating AB Toxin
Turn Gs on Causing Increase in cAMP
Secretion of Cl
Blocks Reabsorption of Na
Rice Water Diarrhea
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1 min
Bacteroides Fragilis
Characteristics
Gram-Negative
Anaerobe
Normal Colonic Flora
Produces Vitamin K
Produces Gas in Tissue
Foul-Smelling
Signs and Symptoms
Gastrointestinal Abscess
Treatment
Penicillin-Resistant
Clindamycin
Metronidazole
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2 mins
Bartonella henselae
Characteristics
Gram-Negative
Pleomorphic
Bacillus
Signs and Symptoms
Cat Scratch Fever
Lymphadenopathy
Bacillary Angiomatosis
Patients with AIDS
Mimics Kaposi Sarcoma
Benign
Reactive Arthritis
Non-Caseating Granuloma
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2 mins

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