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First Aid for the USMLE Step 1 (2021)
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First Aid for the USMLE Step 1 (2021) | Physician Assistant (PA) School Study Aid

Page 167 -
21 Picmonics to Learn | 37 mins
Rotavirus
Characteristics
Reovirus
Non-enveloped
Double-Stranded
RNA Virus
Linear
11 Segments
Triple Icosahedral Capsid
Most Common Cause of Diarrhea Worldwide
Villous Atrophy
Winter Months
Day Care Centers
Treatment
Oral Rehydration
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2 mins
Picornavirus
Characteristics
Non-enveloped
RNA Virus
Icosahedral
Positive Sense
A large polypeptide cleaved by proteases
Viruses
Rhinovirus
Poliovirus
Coxsackievirus
Hepatitis A Virus
Echovirus
Aseptic meningitis
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1 min
Poliomyelitis
Characteristics
Poliovirus
Picornavirus
Fecal-Oral Transmission
Destruction of Anterior Horn
Clinical Features
Flaccid Paralysis
Hyporeflexia
Fasciculations
Diagnosis
Elevated CSF Lymphocytes and Proteins
Normal CSF Glucose
Viral Culture or PCR
Management
Supportive Care
Vaccination
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3 mins
Rhinovirus
Picornavirus
Cause of Common Cold
More than 100 Serologic Types
Destroyed by Stomach Acid
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32 secs
Coxsackievirus
Characteristics
Picornavirus
Signs and Symptoms
Coxsackie A
Febrile Pharyngitis
Hand, Foot, and Mouth Disease
Most Common Cause of Aseptic Meningitis
Late Summer
Coxsackie B
Myocarditis
Dilated Cardiomyopathy
Type 1 Diabetes
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2 mins
Hepatitis A
Characteristics
Picornavirus
4 Week Incubation Period
Fecal-oral
Day Care Centers
Travel to Developing Countries
Signs and Symptoms
Usually Asymptomatic
Acute Disease
Jaundice
Fever
Vomiting
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2 mins
Norovirus
Characteristics
Calicivirus
RNA Virus
Non-enveloped
Icosahedral
SS Positive Linear
Symptoms
Acute Gastroenteritis
Treatment
Supportive Therapy
Considerations
Often found in Cruise Ships
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1 min
Hepatitis C
Characteristics
Enveloped
RNA Virus
Flavivirus
Icosahedral
SS positive Linear
Clinical Features
Most Cases are Due to IV Drug Use
Turns to Chronic Hepatitis in Over 70% of Cases
Cirrhosis
Hepatocellular Carcinoma
Most Common Indication for Liver Transplantation
Associated With Type I MPGN
Porphyria Cutanea Tarda
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2 mins
Yellow Fever Virus
Characteristics
Flavivirus
RNA Virus
Enveloped
Icosahedral
SS Positive Linear
Transmitted By Aedes Mosquitos
Monkey or Human Reservoir
Signs and Symptoms
High fever
Jaundice
Black vomitus
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2 mins
Rubella
Characteristics
RNA Virus
Matonaviridae
Enveloped
Icosahedral
SS Positive Linear
Signs and Symptoms
German Measles or Three-Day Measles
Fever
Postauricular Tenderness
Lymphadenopathy
Truncal Rash
Arthritis
Congenital TORCH Infection
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2 mins
Human Immunodeficiency Virus (HIV) Assessment
Assessment
RNA Retrovirus
CD4+ Helper T Cells
Primary Infection
Flu-like Symptoms
Lymphadenopathy
Symptomatic Stage
Fatigue
Diarrhea
Unexplained Weight Loss
White Spots on Tongue
Persistent Fever
Night Sweats
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2 mins
Adult T Cell Lymphoma
Caused by HTLV 1
Japan, West Africa, Caribbean
Present with cutaneous lesions
Aggressive
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1 min
Coronavirus
Characteristics
RNA Virus
Enveloped
Helical
SS Positive Linear
Symptoms
Common Cold
SARS (Severe Acute Respiratory Syndrome)
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1 min
Influenza Virus
Characteristics
RNA Virus
Orthomyxovirus
Enveloped
Negative Sense
8 Segments
Helical
Hemagglutinin for Viral Entry
Neuraminidase for Virion Release
Genetic Shift
Reassortment of genome to cause major change
Genetic Drift
Minor Antigenic Mutations
Considerations
Reye Syndrome with Aspirin Use
Guillain-Barre Syndrome
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3 mins
Paramyxovirus
Characteristics
Enveloped
RNA Virus
Helical
SS Negative Linear
Nonsegmented
Surface Fusion Protein Causes Multinucleated Cells
Presentation
Measles
Mumps
Bronchiolitis in Babies
Viruses
Parainfluenza
Respiratory Syncytial Virus (RSV)
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2 mins
Parainfluenza Virus
Characteristics
Paramyxovirus
Signs and Symptoms
Croup
Barking Seal Cough
Inspiratory Stridor
Steeple Sign
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2 mins
Rubeola Virus
Characteristics
RNA Virus
Paramyxovirus
Signs and Symptoms
Measles
Rash Spreads From Head to Toe
Koplik Spots First
Red Spots with Blue-White Center on Buccal Mucosa
Cough
Coryza
Conjunctivitis
Subacute Sclerosing Panencephalitis
Giant Cell Pneumonia in Immunosuppressed Patients
Warthin-Finkeldey Multinucleated Giant Cells
Treatment
Vitamin A
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3 mins
Respiratory Syncytial Virus (RSV) Assessment
Mechanism
Viral Infection Affecting Epithelial Cells
Signs and Symptoms
Begins After a Upper Respiratory Infection
Copious Secretions
Coughing and Sneezing
Wheezing
Otitis Media or Conjunctivitis (Possible Ear or Eye Drainage)
Poor Feeding
Tachypnea
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2 mins
Mumps Virus
Characteristics
Paramyxovirus
Signs and Symptoms
Parotitis
Increased Serum Amylase
Orchitis
Oophoritis
Aseptic Meningitis
Pancreatitis
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59 secs
Rabies Virus
Characteristics
Enveloped
RNA Virus
SS Negative Linear
Helical
Bullet-Shaped Envelope
Binds to Acetylcholine Receptor
Retrograde Fashion
Migrates to Saliva
Diagnosis
Negri Bodies
Cytoplasmic Inclusions in Neurons
Purkinje Cells of Cerebellum
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2 mins
Ebola Virus
RNA Virus
Filovirus
Marburg Virus
Linear
Helical
Enveloped
Negative Sense
Bat Reservoir
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1 min

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