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First Aid for the USMLE Step 1 (2021)
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Page 195 -

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First Aid for the USMLE Step 1 (2021) | Physician Assistant (PA) School Study Aid

Page 195 -
5 Picmonics to Learn | 11 mins
Fluoroquinolones Antibiotics
-floxacin
Mechanism of Action
Inhibits Topoisomerase II & IV
Bactericidal
Indications
Gram-negative Rods
Pneumonia
Gastrointestinal Infections
Urinary Tract Infection
Genital Infections
Drugs
Levofloxacin
Ciprofloxacin
Has Pseudomonas Coverage
Considerations
Avoid Polyvalent Cations
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3 mins
Fluoroquinolones Toxicities
Diarrhea
Skin Rash
Headache
Tendon Rupture in Adults
Myalgias in Kids
Damage to Cartilage
Teratogen
QT Prolongation
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1 min
Clostridium difficile (Clostridioides difficile) Treatments
Oral Vancomycin
Fidaxomicin
Metronidazole
Stool Transplant
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2 mins
Daptomycin (Cubicin)
Mechanism Of Action
Lipopeptide Antibiotic
Disrupts Cell Membrane
Causes Rapid Depolarization
Indication
Gram-Positive Cocci
MRSA
Side Effects
Myopathy
Rhabdomyolysis
Peripheral Neuropathy
Considerations & Patient Education
Inactivated by Surfactant
Not Used (Avoid) for Pneumonia
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3 mins
Metronidazole
Mechanism of Action
Bactericidal
Forms Free Radical Toxic Metabolites
Damages DNA
Indications
Giardia lamblia
Entamoeba Histolytica
Trichomonas
Gardnerella
Anaerobes
Side Effects
Metallic taste
Disulfiram like Reaction with Alcohol
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2 mins

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