Blood Types
- Allele A is Dominant
- Allele B is Dominant
- Allele O is Recessive
- Genotypes AA and AO have Type A Blood
- Genotypes BB and BO have Type B Blood
- Genotype AB is co-dominant and has Type AB Blood
- Genotype OO Results in Type O Blood
Blood Types and Compatibilities
- No Antigens (Type O Blood)
- Universal Donor
- A Antigen (Type A Blood)
- B Antigen (Type B Blood)
- AB Antigen (Type AB Blood)
- Universal Recipient
- Rh (Rhesus) Antigen
- Never Rh+ to Rh-
- Blood Transfusion
- Obstetric Patient
Whole Blood Composition
- Plasma
- Electrolytes And Other Solutes
- Proteins
- Albumin
- Fibrinogen
- Globulins
- Water
- Formed Elements
- Buffy Coat
- White Blood Cells (WBC)
- Platelets
- Red Blood Cells (RBC)
Rh Hemolytic Disease of the Fetus and Newborn
- Rh (Rhesus) Incompatibilities
- Rh(D)- Mother and Rh(D)+ Fetus
- Anti-Rh(D) Antibodies
- Hemolytic Anemia
- Hydrops Fetalis
- Neonatal Jaundice
- Kernicterus
- Positive Coombs Test
- Ultrasound
- RhoGAM [Anti-Rh(D) Immunoglobulin]
- Intrauterine Blood Transfusion
- Phototherapy
- IVIG (Intravenous Immunoglobulin)
ABO Hemolytic Disease of the Fetus and Newborn
- ABO Incompatibilities
- Type O Mother and Type A/B Fetus
- Anti-A or Anti-B Antibodies
- Hemolytic Anemia
- Often Asymptomatic
- Neonatal Jaundice
- Negative Coombs Test
- Phototherapy
RhoGam [Rho(D) Immune Globulin]
- Antepartum Prevention at 28 weeks
- Suppress Antibody Production
- Lysis of Fetal RBC in Maternal Bloodstream
- Myalgia and Lethargy
- Negative Coombs Test
- Standard Dose 300 mcg
- Microdose 50 mcg
- Blood Product