Thiazide Diuretics
- Early Distal Tubule
- Inhibits Na/Cl Reabsorption
- Sulfa Drug
- Hyperglycemia
- Hyperlipidemia
- Hypercalcemia
- Hyperuricemia
- Hyponatremia
- Hypokalemic Metabolic Alkalosis
Nonselective Beta-Blockers
- "-olol" Suffix
- Nonselective
- Propranolol
- Timolol
- Nadolol
- Partial β Agonist
- Pindolol
- Nonselective β with α Blocking
- Carvedilol
- Labetalol
Systemic Effects of Beta-Blockers
- Respiratory
- Bronchoconstriction
- Metabolic
- Decreased Insulin
- Decreased Glycolysis and Lipolysis
- Eye
- Reduces Intraocular Pressure
Hydrochlorothiazide HCTZ
- Inhibits Reabsorption NaCl and H2O
- Edema
- Mild to Moderate Hypertension
- Hypokalemia
- Hyponatremia
- Dehydration
- Hyperglycemia
- Gout
- Sulfa Allergy
- Pregnancy and Breastfeeding
Loop Diuretics
- Thick Ascending Limb of Loop of Henle
- Inhibits Na+-K+-2Cl- Symporter
- Sulfa Drug
- Furosemide
- Lasix
- Gout
- Ototoxicity
- Hypocalcemia
- Hypokalemia
Spironolactone (Aldactone)
- Inhibition of Aldosterone
- Potassium Retention
- Hypertension
- Edema
- Heart Failure
- Hyperkalemia
- Endocrine Effects
- Avoid Potassium Supplements
K+ Sparing Diuretics
- CHF and Hypertension
- Hypokalemia
- Hyperaldosteronism
- Collecting Tubule
- Spironolactone
- Competitive Aldosterone Receptor Antagonist
- Amiloride and Triamterene
- Block Na+ Channels
- Hyperkalemia
- Gynecomastia
ACE Inhibitors
- -Pril Suffix
- Hypertension
- CHF
- Diabetic Nephropathy
- Inhibits ACE
- Decreases GFR
- Inhibits Constriction of Efferent Arteriole
- Increased Bradykinin
- Cough
Angiotensin Receptor Blockers (ARBs)
- -sartan suffix
- Hypertension
- CHF
- Diabetic Nephropathy
- Angiotensin II Receptor Blockers
- Hyperkalemia
- Pregnancy
Prazosin (Minipress)
- -osin suffix
- Selective Alpha-1 Receptor Blocker
- Hypertension
- Benign Prostatic Hyperplasia (BPH)
- Nightmares
- Orthostatic Hypotension
- Tachycardia
- Priapism / Inhibition of Ejaculation
- Nasal Congestion
- First Dose Effect
- Administer at Bedtime
Selective Beta-1 Blockers
- "-olol" Suffix
- Beta-1 Selective
- Atenolol
- Esmolol
- Metoprolol
- Partial Beta agonists
- Acebutolol
Class IV Antiarrhythmics (Ca2+ Channel Blockers)
- SVT
- Subarachnoid Hemorrhage
- Decrease Conduction Velocity
- Increase PR Interval and ERP
- Verapamil
- Diltiazem
- Nimodipine
- Cardiovascular
- Constipation
Calcium Channel Blockers (Verapamil and Diltiazem)
- Slows AV Conduction
- Angina Pectoris
- Arrhythmias
- Essential Hypertension
- Bradycardia
- Hypotension
- Constipation
- Peripheral Edema
- Gingival Hyperplasia
- Medication Education