Colorectal Cancer Assessment
- 3rd Most Common Cancer
- Change in Bowel Habits
- Bowel Obstruction
- Rectal Bleeding
- Anemia
- Weight Loss
- Ascites
- Colonoscopy
- FOBT and FIT
Colorectal Cancer Interventions
- Surgical Colon Resection
- Radiation
- Chemotherapy
- Bowel Cleansing
- Screening
- Colostomy
- Dietary Consult
- Body Image
Types of Hernias
- Hiatal
- Gastroesophageal Reflux Disease (GERD)
- Inguinal
- Men
- Femoral
- Women
- Incisional
- Umbilical
- Strangulation
Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
- Autosomal Dominant
- Defective DNA Mismatch Repair
- 80% Risk of Colon Cancer Development
- Proximal (Right) Colon
- Type II associated with Endometrial, Ovarian and Skin Cancers
- 3 Relatives with Colon Cancer
- Occurs Across 2 Generations
- 1 Relative Diagnosed < 50 Years Old
- Frequent Screening
- Colectomy
Peutz-Jeghers Syndrome
- Symptomatic Age: 10-30 Years
- LKB1/STK11 Gene Mutation
- Autosomal Dominant
- Benign GI Hamartomatous Polyps
- Mucocutaneous Hyperpigmentation
- Positive Family History
- Increased Risk of Colorectal Carcinoma
Fluorouracil (5-FU)
- Antimetabolite
- "Thymine-less Death"
- Slow-growing Solid Tumors
- Co-administered with Leucovorin for Stomach Cancer
- Basal Cell Carcinoma (Topical)
- Myelosuppression
- Mucositis
- Severe Diarrhea