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PANCE Prep Pearls: 3rd Ed. (2019) | Physician Assistant (PA) School Study Aid
Mycobacterium leprae
- Characteristics
- Acid-Fast
- Aerobic
- Likes Cool Temperature
- Diagnosis by Skin Biopsy or PCR
- Lepromatous Leprosy
- Th2 Response
- Leonine Facies
- Tuberculoid Leprosy
- TH1 Response
- Hypoesthetic Skin Plaques
- Granulomatous Response
- Treatment
- Dapsone
- Rifampin
- Clofazimine
2 mins
Mycobacterium Tuberculosis Disease
- CONSTITUTIONAL SYMPTOMS/PULMONARY TUBERCULOSIS
- Fever
- Night Sweats
- Weight Loss
- Hemoptysis
- EXTRA-PULMONARY TUBERCULOSIS
- Extrapulmonary Disease
- Addison's Disease
- CNS
- Liver
- Kidneys
- GI
- Bones
- Pott's Disease
3 mins
Tuberculosis Skin Mantoux Test (PPD)
- Delayed Hypersensitivity (Cell Mediated Response)
- Intradermal Injection
- Read 48-72 hours
- Positive Results
- ≥ 5 mm Induration
- Immunosuppressed
- ≥ 10 mm Induration
- High Risk Patients
- ≥ 15 mm Induration
- Considerations
- Chest X-Ray
3 mins
Mycobacterium Tuberculosis Characteristics
- Characteristics
- Mycolic Acid Cell Wall
- Acid-fast
- Carbolfuchsin Stain Red
- Lowenstein-Jensen Agar
- Serpentine Cord Factor
- Primary TB
- Primary TB
- Caseating Granuloma
- Ghon Focus
- Hilar Lymph Nodes
- Ghon Complex
- Reactivation TB
- Reactivation TB
- Reactivation in Apex
3 mins
Ghon Complex
- Calcified Focus of Infection
- Hilar Lymph Nodes
- Primary Tuberculosis
- Typically in Children
1 min
Tuberculosis Assessment
- Etiology
- Airborne Droplet
- Assessment
- 3 Week Productive Cough
- Night Sweats
- Chest Pain
- Fever
- Weight Loss
- Fatigue
- Diagnosis
- Chest X-Ray
- Blood Tests
- Mantoux Skin Test
- 3 Positive Sputum Tests
1 min
Tuberculosis Intervention
- Hospital Care
- Airborne Isolation
- Drug Therapy
- Combination Drug Therapy (RIPE)
- 6-12 Months
- Considerations
- DOT
- BCG Vaccination
- Medication Education
- 3 Negative Sputum Specimens
- Infection Control
2 mins
Rifampin
- Tuberculosis (TB)
- Blocks RNA Polymerization
- Haemophilus influenzae Type B
- Leprosy
- Meningitis
- P450 inducer
- Red-orange urine
55 secs
Isoniazid (INH)
- Mechanism
- Interferes with DNA Metabolism
- Indications
- Tuberculosis (TB)
- Side Effects
- Optic Neuritis
- Nausea and Vomiting
- Hepatotoxicity
- Peripheral Neuropathy
- Considerations
- Vitamin B6 Prophylaxis
- Monitor AST/ALT
2 mins
Ethambutol (Myambutol)
- Mechanisms
- Inhibits RNA Synthesis
- Bacteriostatic
- Indications
- Tuberculosis (TB)
- Side Effects
- Optic Neuritis
- Red/Green Color Blindness
- Gouty Arthritis
- Consideration
- Monitor Vision Acuity
2 mins
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