Mycobacterium leprae
- Acid-Fast
- Aerobic
- Likes Cool Temperature
- Diagnosis by Skin Biopsy or PCR
- Th2 Response
- Leonine Facies
- TH1 Response
- Hypoesthetic Skin Plaques
- Granulomatous Response
- Dapsone
- Rifampin
- Clofazimine
Mycobacterium Tuberculosis Disease
- Fever
- Night Sweats
- Weight Loss
- Hemoptysis
- Extrapulmonary Disease
- Addison's Disease
- CNS
- Liver
- Kidneys
- GI
- Bones
- Pott's Disease
Tuberculosis Skin Mantoux Test (PPD)
- Delayed Hypersensitivity (Cell Mediated Response)
- Intradermal Injection
- Read 48-72 hours
- ≥ 5 mm Induration
- Immunosuppressed
- ≥ 10 mm Induration
- High Risk Patients
- ≥ 15 mm Induration
- Chest X-Ray
Mycobacterium Tuberculosis Characteristics
- Mycolic Acid Cell Wall
- Acid-fast
- Carbolfuchsin Stain Red
- Lowenstein-Jensen Agar
- Serpentine Cord Factor
- Primary TB
- Caseating Granuloma
- Ghon Focus
- Hilar Lymph Nodes
- Ghon Complex
- Reactivation TB
- Reactivation in Apex
Ghon Complex
- Calcified Focus of Infection
- Hilar Lymph Nodes
- Primary Tuberculosis
- Typically in Children
Tuberculosis Assessment
- Airborne Droplet
- 3 Week Productive Cough
- Night Sweats
- Chest Pain
- Fever
- Weight Loss
- Fatigue
- Chest X-Ray
- Blood Tests
- Mantoux Skin Test
- 3 Positive Sputum Tests
Tuberculosis Intervention
- Airborne Isolation
- Combination Drug Therapy (RIPE)
- 6-12 Months
- DOT
- BCG Vaccination
- Medication Education
- 3 Negative Sputum Specimens
- Infection Control
Rifampin
- Tuberculosis (TB)
- Blocks RNA Polymerization
- Haemophilus influenzae Type B
- Leprosy
- Meningitis
- P450 inducer
- Red-orange urine
Isoniazid (INH)
- Interferes with DNA Metabolism
- Tuberculosis (TB)
- Optic Neuritis
- Nausea and Vomiting
- Hepatotoxicity
- Peripheral Neuropathy
- Vitamin B6 Prophylaxis
- Monitor AST/ALT
Ethambutol (Myambutol)
- Inhibits RNA Synthesis
- Bacteriostatic
- Tuberculosis (TB)
- Optic Neuritis
- Red/Green Color Blindness
- Gouty Arthritis
- Monitor Vision Acuity