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Endocrinology
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Adrenal

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Endocrinology | Physician Assistant (PA) School Study Aid

Adrenal
7 Picmonics to Learn | 14 mins
Adrenal Gland (Basic)
Characteristics
Adrenal Cortex
RAAS Stimulates Aldosterone
CRF (CRH) acts on Anterior Pituitary Gland to Release ACTH
Cortisol Released
Androgens Released
Adrenal Medulla
Epinephrine & Norepinephrine
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2 mins
Adrenal Gland (Advanced)
Characteristics
Adrenal Cortex
Zona Glomerulosa
Aldosterone
Zona Fasciculata
Cortisol
Zona Reticularis
Androgens
Adrenal Medulla
Chromaffin Cells
Epinephrine & Norepinephrine
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2 mins
Low Blood Pressure Response
Characteristics
Posterior Pituitary Releases Vasopressin
Vasoconstriction
Adrenal Cortex Releases Aldosterone
Increased Na+ and H2O Reabsorption
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1 min
High Blood Pressure Response
Characteristics
Atria Release Atrial Natriuretic Peptide
Vasodilation
Antagonizes Aldosterone
Na+ and Water Excreted
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1 min
Renin Angiotensin Aldosterone System (RAAS) Regulators
Activators
Hypotension
Hypovolemia
Decreased NaCl Delivery to Macula Densa
Sympathetic Stimuli
Key Mediators
Angiotensin II
Aldosterone
Antidiuretic Hormone
Negative Feedback
Atrial Natriuretic Peptide and Brain Natriuretic Peptide
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2 mins
Angiotensin II Synthesis
Juxtaglomerular Apparatus
Juxtaglomerular Cells
Mesangial Cells
Macula Densa
Distal Tubule
KEY MEDIATORS
Angiotensinogen
Secreted from Liver
Renin
Secreted from Juxtaglomerular Cells
Catalyzes Angiotensinogen to Angiotensin I
Angiotensin Converting Enzyme (ACE)
Pulmonary Capillaries
Catalyzes Angiotensin I to Angiotensin II
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3 mins
Angiotensin II Effects
Effects On Vasculature
Increases Vascular Smooth Muscle Contraction
Increases Blood Pressure
Effects on Kidney
Efferent Arteriole Vasoconstriction
Increases GFR
Proximal Tubule
Sodium and Water Reabsorption
Adrenal Cortex
Increases Aldosterone Secretion
Effects on CNS
Stimulates Posterior Pituitary Gland to Secrete Vasopressin (ADH)
Stimulates Thirst in Hypothalamus
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2 mins

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