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Roseola

Rose-O

Picmonic

Roseola is a common exanthem in young children that presents with a high fever followed by a rash. It is usually caused by Human Herpesvirus 6 (HHV-6), which is an enveloped linear double-stranded DNA virus. Children will have 3-5 days of a high fever, which may exceed 40C or 104F, causing some children to develop febrile seizures. Following this, a diffuse macular rash starts on the trunk and spreads to the face and extremities.

7 KEY FACTS

An exanthem is a widespread rash usually occurring in children and can be caused by toxins or drugs, microorganisms, or can result from autoimmune disease.

This virus is in the herpesviridae family and is HHV-6.

Roseola is an enveloped virus. Viral envelopes are outer membranes that cover their protein capsids that help to enter host cells.

Roseola is a DNA virus, meaning its genetic code consists of deoxyribonucleic acid as opposed to ribonucleic acid. Like all DNA viruses except parvovirus, HHV 6 has double stranded DNA genome.

Roseola has DNA in a linear arrangement as opposed to a circular formation.

Roseola usually begins with a fever that exceeds 40C or 104F and lasts for 3-5 days. In some children this can lead to febrile seizures.

Roseola typically starts with several days of a high fever and is then followed by the development of a diffuse macular rash that begins on the trunk. This rash may spare the face or appear on the face following the development of the rash on the trunk.

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