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Yolk Sac Tumor

Yolk Sac with Tumors

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Yolk sac tumor, or endodermal sinus tumor, is the most common germ-cell ovarian tumor found in infants. It is aggressively malignant and presents as a yellow, non-encapsulated mucinous mass. In 50% of cases, glomerulus-like structures called Schiller-Duval bodies can be found in histological examination. AFP is used as a tumor marker.

5 KEY FACTS

Yolk-sac tumor is a germ-cell tumor, also known as endodermal sinus tumor. It is the most common germ cell tumor found in infants, but is rare overall.

AFP, or alpha-fetoprotein is the tumor marker used to detect yolk sac tumors.

This type of ovarian tumor shows aggressive malignancy in the ovaries and sacrococcygeal area of younger children.

Yolk sac tumors often present with a yellow non-encapsulated mucinous mass. This is described as friable and solid.

Schiller-Duval bodies are glomerulus-like structures and are present in 50% of cases of yolk sac tumors. If found, these structures are pathognomonic for yolk sac tumors.

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