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Shea's Playlist
Foot Bones
Tiger Cubs Need MILC
Talus
Calcaneus
Navicular
Medial Cuneiform
Intermediate Cuneiform
Lateral Cuneiform
Cuboid
1 min
Lower Limb Bones - Femur
Femur
Head
Neck
Greater Trochanter
Lesser Trochanter
Gluteal Tuberosity
Pectineal Line
Linea Aspera
Epicondyles
Condyles
Adductor Tubercle
2 mins
Lower Limb Bones - Tibia and Fibula
Characteristics
Tibia
Tibial Plateau
Medial and Lateral Condyles
Tibial Tuberosity
Gerdys Tubercle
Fibular Notch
Medial Malleolus
Fibula
Fibular Head
Lateral Malleolus
2 mins
Pelvic Bones
Ilium
Iliac Crest
ASIS (Anterior Superior Iliac Spine)
AIIS (Anterior Inferior Iliac Spine)
Acetabulum
Pubis
Pubic Symphysis
Obturator Foramen
Ischium
Sacrum
Coccyx
1 min
Gardnerella vaginalis
Signs and Symptoms
Bacterial Vaginosis
Not an STD
Fishy Smell
Whiff Test
Grey Vaginal Discharge
Increase pH
Clue Cells
Squamous Epithelial Cells Covered with Bacteria
Mobiluncus Coinfection
Treatment
Metronidazole
2 mins
Chlamydia
Mechanism
Chlamydia trachomatis
Assessment
May Be Asymptomatic
Dysuria
Epididymitis
Discharge
Dyspareunia
Interventions
Doxycycline
Azithromycin
No Intercourse for 1 Week
Treat Partners
2 mins
Chlamydia Characteristics
Characteristics
Cannot Make ATP
Elementary body infects
Intraepithelial
Reticulate Body Replicates
Diagnosis
Cell Wall Lacks Muramic Acid
Giemsa Stain
Inclusion Bodies
Treatment
Azithromycin (Preferred)
Doxycycline
2 mins
Legionella Characteristics
Characteristics
Bacillus
Poor Gram Stain
Charcoal Yeast with Iron and Cysteine
Silver Stain
Water Sources
Smokers and Heavy Drinkers
Detect Antigen in Urine
2 mins
Legionella Disease
Signs and Symptoms
High Fever
Diarrhea
Increased Liver Enzymes
Hyponatremia
Type IV Renal Tubular Acidosis
Severe Atypical Pneumonia
Pontiac Fever
Treatment
Fluoroquinolones
Macrolides
2 mins
Mycoplasma Pneumoniae
Characteristics
No Cell Wall and No Gram Stain
Cholesterol Membrane
Eaton's Agar
Mulberry Colonies
Disease
Atypical pneumonia
Military Recruits
Cold IgM Autoimmune Hemolytic Anemia
Erythema Multiforme
Treatment
Tetracycline
Erythromycin
2 mins
Whipple's Disease
Tropheryma Whipplei
Gram-Positive
Middle-aged, Caucasian men and Farmers
Malabsorption
Mesenteric Nodes
Arthralgias
Cardiac Symptoms
Neurologic Symptoms
PAS-positive Foamy Macrophages
1 min
Glycolysis
Characteristics
Glucose
Hexokinase or Glucokinase
Glucose-6-phosphate
Fructose-6-phosphate
Phosphofructokinase-1 (PFK-1)
Fructose-1,6-bisphosphate
Aldolase
Glyceraldehyde-3-Phosphate
1,3-bisphosphoglycerate
3-phosphoglycerate
2-phosphoglycerate
Phosphoenolpyruvate (PEP)
Pyruvate Kinase
Pyruvate
Pyruvate Dehydrogenase
Acetyl-CoA
4 mins
Fructose Metabolism
Liver Fructose Metabolism
Fructose
Fructokinase
Fructose-1-Phosphate
Aldolase B
DHAP
Glyceraldehyde
Glyceraldehyde-3-Phosphate
2 mins
Citric Acid Cycle (Krebs Cycle)
Characteristics
Acetyl-CoA + Oxaloacetate
Citric Acid
Isocitric Acid
Produces NADH
Alpha-Ketoglutaric Acid
Produces NADH
Succinyl CoA
Produces GTP
Succinate
Produces FADH2
Fumarate
Uses Water
Malate
Produces NADH
Oxaloacetate
4 mins
Urea Cycle
Mitochondria
N-Acetylglutamate
Carbamoyl Phosphate Synthetase I
NH3 + CO2
Carbamoyl Phosphate
Ornithine Transcarbamylase
Citrulline
Cytosol
Aspartate
Argininosuccinate
Fumarate
Arginine
H2O to Urea
Ornithine
3 mins
Lipid Metabolism and Ketogenesis
Lipid Metabolism
Acetyl-CoA
Biotin Cofactor
Malonyl-CoA
Fatty Acids
Triglycerides
Glycerol
DHAP
Acetoacetyl-CoA
HMG-CoA
HMG-CoA Reductase
Mevalonate
Cholesterol
Ketogenesis
Acetoacetate
Beta-Hydroxybutyrate
4 mins
Gluconeogenesis
OVERVIEW
Produces Glucose from Non-Carbohydrate Substrates
Upregulated by Glucagon and Cortisol
PATHWAY
Pyruvate
Pyruvate Carboxylase
Oxaloacetate
Phosphoenolpyruvate (PEP) Carboxykinase
Phosphoenolpyruvate (PEP)
Fructose-1,6-bisphosphate
Fructose-1,6-bisphosphatase
Fructose-6-phosphate
Glucose-6-phosphate
Glucose 6-phosphatase
Glucose
Clinical Relevance
Von Gierke Disease
4 mins
Energy Releasing Pathways: Accounting
Characteristics
Anaerobic Respiration
2 ATP
2 NADH
Aerobic Respiration
8 NADH
2 FADH2
2 ATP
Oxidative Phosphorylation
34 ATP
2 ATP Lost
36 Net Total ATP
2 mins
Oxidative Phosphorylation
Inner Mitochondrial Membrane
Electron Transport Chain
Oxygen is Final Electron Acceptor
Proton Pump
Proton Motive Force
ATP Synthase
1 NADH 2.5 ATP
1 FADH2 1.5 ATP
3 mins
Anaerobic Respiration
Cytosol
Glucose
Glycolysis
Substrate-level Phosphorylation
2 NADH
2 Net ATP
2 Pyruvate
Fermentation
NAD+ Regeneration
Waste Byproduct
2 mins
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