OnlineMedEd Shared "The Endocrine Pancreas" - 5 Picmonics
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The Endocrine Pancreas
Pancreas
- Characteristics
- Acinar Cells Release Digestive Enzymes
- Ductal Epithelial Cells Release Bicarbonate
- Islets of Langerhans
- Beta Cells Release Insulin
- Alpha Cells Release Glucagon
- Delta Cells Release Somatostatin
- Somatostatin Inhibits Alpha and Beta Cells
3 mins
Pancreatin, Pancrelipase (Pancreatic Enzymes)
- Mechanism
- Pancreatic Enzymes
- Indications
- Cystic Fibrosis
- Pancreatic Insufficiency
- Side Effects
- GI Distress
- Considerations
- Inactivated by Gastric Acid
- 24 Hour Fat Excretion
- Take with Every Meal and Snack
2 mins
Small Intestine Digestion
- Brush border enzymes
- Pancreatic Enzymes are secreted via a Duct
- Pancreas secretes bicarbonate
- Brush Border activates Pancreatic Trypsin
- Trypsin activates Chymotrypsin
- Trypsin and Chymotrypsin digest Proteins
- Gallbladder Releases Bile
- Pancreatic Lipase breaks down Lipids
- Goblet cells secrete mucus
- Pancreatic Amylase breaks down Carbohydrates
- Pancreatic Nucleases breakdown DNA/RNA
- Digestion occurs in the Duodenum
2 mins
MEN 1 (Multiple Endocrine Neoplasia)
- Pathophysiology
- Autosomal Dominant
- Menin Mutation (Tumor Suppression Gene)
- Chromosome 11
- Signs and Symptoms
- Pancreatic Endocrine Tumors
- Pituitary Tumors
- Parathyroid Adenomas
2 mins
Zollinger-Ellison Syndrome Diagnosis and Treatment
- Diagnosis
- Gastrin > 1000 pg/mL
- Positive Secretin Stimulation Test
- Treatment
- High-Dose PPI
- Octreotide
- Surgical Resection
3 mins
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