Janani Shared "Z Resp" - 7 Picmonics
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Z Resp
Lung development
- Embryonic
- Wk 4-7
- TE fistulas
- Pseudoglandular
- Wk 5-17
- Modest capillary network
- Canalicular
- Wk 16-26
- Respiration possible at 25 weeks
- Saccular
- 26-birth
- terminal sacs (primary septation)
- Primary septation of alveoli
- Alveolar
- Wk 36-8yo
- adult sacs
- Secondary septation of alveoli
- pneumocytes develop
Methemoglobinemia
- Methemoglobinemia
- Fe3+
- chocolate colored blood
- Caused by sulfa, nitrate, or benzocaine
- Can treat cyanide poisoning
- Antidote is methylene blue and vitamin c
Cyanide Toxicity
- Mechanism
- Impedes Oxidative Phosphorylation
- Lactic Acidosis
- Metabolic Acidosis
- Symptoms
- Skin Flushing
- Tachycardia
- Tachypnea
- Vomiting
- Change In LOC (Altered Mental Status)
- Seizures
- Coma
- Treatment
- Hydroxocobalamin
- Sodium Thiosulphate
- Nitrates
Toxins Affecting the Electron Transport Chain
- Complex I
- NADH Dehydrogenase
- Amobarbital
- Rotenone
- Complex III
- Coenzyme Q Oxidoreductase
- Antimycin A
- Complex IV
- Cytochrome C
- Carbon Monoxide
- Cyanide
- Complex V
- ATP Synthase
- Oligomycin
- Proton Gradient
- 2,4-Dinitrophenol
- Aspirin
- Uncoupling Agents
Winter's Formula
- Evaluates Respiratory Compensation
- Used in Metabolic Acidosis
- Equation
- (HCO3 x 1.5 ) + 8 plus-minus 2 = PCO2
- Steps
- Bicarbonate (HCO3) x 1.5
- + 8
- ± 2
- = Expected Value for PCO2
2 mins
Sarcoidosis Characteristics and Labs
- Mechanism
- Unknown Mechanism
- Immune-mediated
- Noncaseating granulomas
- Vitamin D activation
- Labs
- Hypercalcemia
- Elevated ACE
- Asteroid bodies
- X-Ray shows Bilateral hilar lymphadenopathy
- Treatment
- Corticosteroids
1 min
Sarcoidosis Symptoms
- Black Females
- Symptoms
- Asymptomatic
- Uveitis
- Interstitial Fibrosis
- Erythema Nodosum
- Hepatomegaly
- Myocardial Sarcoidosis
- Lupus Pernio
1 min
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