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Cardiac Pathology
Rheumatic Fever
Pathophysiology
Pharyngeal Infection with Strep Pyogenes (Group A Strep)
Rheumatic Heart Disease
Signs and Symptoms
Aschoff Bodies
Anitschkow's Cells
Early Death Due to Myocarditis
Migratory Polyarthritis
Subcutaneous Nodules
Erythema Marginatum
Chorea
Diagnosis
Elevated ESR
2 mins
Bacterial Endocarditis
Signs and Symptoms
Fever
New murmur
Janeway Lesions
Splinter Hemorrhages
Roth spots/round white spots on retina
Osler nodes/tender lesions on finger or toe pads
Anemia
2 mins
Hypertrophic Cardiomyopathy Mechanisms
Pathophysiology
2/3 Autosomal-Dominant
1/3 Sporadic Type
Mutation in Gene for Sarcomere Protein
Cardiac Myosin Binding Protein C
Asymmetric Septal Hypertrophy
Outflow Tract Obstruction
Diastolic Dysfunction
2 mins
Hypertrophic Cardiomyopathy Signs, Symptoms and Treatment
Signs and Symptoms
Sudden Death Of Young Athlete
Heart Failure
Angina
Arrhythmias
Syncope
Harsh Systolic Ejection Murmur
S4 Heart Sound
Treatment
Beta Blocker
Non-dihydropyridine Calcium Channel Blocker
2 mins
Dilated Cardiomyopathy
Chronic Alcohol Abuse
Doxorubicin Toxicity
Cocaine Use
Wet Beriberi
Hemochromatosis
Coxsackie B
Chagas Disease
Peripartum
S3
Eccentric Hypertrophy
2 mins
Restrictive Cardiomyopathy
Sarcoidosis
Amyloidosis
Post-radiation Fibrosis
Endocardial Fibroelastosis
Löffler's or Loeffler's Syndrome with Eosinophilia
Hemochromatosis
2 mins
Sarcoidosis Characteristics and Labs
Mechanism
Unknown Mechanism
Immune-mediated
Noncaseating granulomas
Vitamin D activation
Labs
Hypercalcemia
Elevated ACE
Asteroid bodies
X-Ray shows Bilateral hilar lymphadenopathy
Treatment
Corticosteroids
1 min
Sarcoidosis Symptoms
Black Females
Symptoms
Asymptomatic
Uveitis
Interstitial Fibrosis
Erythema Nodosum
Hepatomegaly
Myocardial Sarcoidosis
Lupus Pernio
1 min
Amyloidosis
Etiologies
Primary
Multiple Myeloma
Secondary
Tuberculosis (TB)
Rheumatoid Arthritis
Pathology
Congo Red Stain
Apple Green Birefringence
Complications
Nephrotic Syndrome
2 mins
Cardiac Tamponade
Mechanism
Fluid in the Pericardial Sac
Pericarditis
Decreased Cardiac Output
Signs/Symptoms
Beck's Triad
Hypotension
Jugular Venous Distention (JVD)
Distant Heart Sounds
Pulsus Paradoxus
Electrical Alternans
Treatment
Pericardiocentesis
1 min
Acute Pericarditis Causes
Idiopathic
Infection
Trauma
Cardiac
Myocardial Infarction
Autoimmune Diseases
Uremia
Tumor
Radiation
2 mins
Acute Pericarditis Assessment
Pericardial Sac Inflammation
Assessment
Sharp Chest Pain
Increased with Inspiration
Pain Decreased by Leaning Forward
Pericardial Friction Rub
Diffuse ST-Elevation
T Wave Inversion
Fever
Considerations
May Be Asymptomatic
Cardiac Tamponade
2 mins
Acute Pericarditis Interventions
Interventions
Treat Underlying Disorder
Antibiotics
Colchicine + NSAIDs
Corticosteroids
Place Patient Upright with Head of Bed at 45°
Pericardiocentesis
Pericardial Window
2 mins
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