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Allie Shared "F. Pharm: Sedative Hypnotics" - 6 Picmonics

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F. Pharm: Sedative Hypnotics

Benzodiazepines Overview
Indications
First Line for Status Epilepticus
Anesthesia Induction
Anxiety
Eclampsia
Detoxification
Mechanism of Action
'-zepam' and '-zolam" Suffix
Increase Frequency of Cl- Channel Opening
Side Effects
Decrease REM Sleep
CNS Depression
Dependence
Antidote
Flumazenil for Overdose
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2 mins
Benzodiazepine Antidote
Antidote
Flumazenil
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40 secs
Barbiturates
Barb- Drug Names
Indications
Seizure Treatment
Anesthesia Induction
Mechanism of Action
Increased Duration of Cl- Channel Opening
Decrease Neuron Firing
Side Effects
Sedation
Cardiovascular and Respiratory Depression
CNS Depression
P450 inducer
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2 mins
Phenobarbital (Barbiturates)
Mechanism
Barbiturate
Indications
Seizures
Side Effects
Ataxia
Paradoxical Excitement
Fatigue/Drowsiness
Considerations
Monitor Plasma Levels
High Potential for Abuse
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1 min
Nonbenzodiazepine Hypnotics
Indications
Insomnia
Mechanism of Action
Short Half-Life
Acts on BZ1 GABA receptor
Less dependence
Drugs
Zolpidem (Ambien)
Side Effects
Ataxia, confusion
Antidote
Flumazenil for Overdose
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1 min
Buspirone
Indications
Generalized Anxiety
Mechanism of Action
Releases Dopamine and NE
Stimulates 5-HT1A receptors
Side Effects
Low Side Effect Profile
Safer with Alcohol than Other Anxiolytics
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1 min

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