Tanner Shared "GI system" - 36 Picmonics
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GI system
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
Metoclopramide
- Indications
- Antiemetic
- Promotility Agent
- Mechanism
- Increased Resting Tone
- Antagonist at D2 Receptor
- Side Effects
- Parkinsonian Symptoms
- Galactorrhea
- Contraindication
- Small Bowel Obstruction
- Parkinson's Disease
2 mins
Promethazine (Phenergan)
- Mechanism
- Histamine H1 Receptor Antagonist
- Weak Dopamine Antagonist
- Indications
- Nausea and Vomiting
- Motion Sickness
- Side Effects
- Respiratory Depression
- Sedation
- Anticholinergic Effects
- Extrapyramidal Symptoms
- Considerations
- Use Large Bore IV
- Monitor for Tissue Necrosis
2 mins
Bulk-Forming Laxatives
- Bulk-forming Laxatives
- Psyllium (Metamucil)
- Methylcellulose (Citrucel)
- Polycarbophil (Fibercon)
- Uses
- geriatric
- Pregnancy
- Drug Interactions
- Binds to other drugs and reduces absorption
- Contraindications
- Stenosis
- Ulceration
- Fecal obstruction
- Other uses
- Mild diarrhea
- Irritable Bowel Syndrome
Emollient Laxatives
- Emollient Laxatives
- Docusate sodium (Colace)
- Uses
- After Myocardial Infarction
- Post rectal surgery
- Opioids
- Pregnant Women
- Contraindications
- Appendicitis
- Fecal impaction
Lubricants
- Lubricants
- Mineral Oil
- CAUTION
- Chronic use
- Elderly
- Risk of Aspiration
- Fat soluable vitamins
Stimulant Laxatives
- Diphenylmethane Derivatives
- Bisacodyl (Dulcolax):
- Indications
- Children >12 years old
- ADR's
- Avoid with antacids/milk
- Pink Colored urine/feces
- Atonic Colon
- Anthraquinone Laxatives
- Senna (Senokot)
- Indications
- Same as Bisacodyl
- ADR's
- Yellow-brown to red urine
- Interstitial Nephritis
- Atonic Colon
- Contraindications
- Pregnancy
- Interstitial Nephritis
Saline Cathartics
- Saline Cathartics
- Magnesium Hydroxide
- Magnesium Sulfate
- Sodium phosphate
- Magnesium citrate
- Castor Oil
- Glycerin Suppository
Glycerin/Hyperosmotic
- Polyethylene glycol
- Polyethylene glycol
- GoLytely
Opioid Induced Constipation (OIC)
- Noloxegol - Movantik
- Noloxegol
- MOA
- Peripheral opioid Antagonist
- Lubiprostone - Amitiza
- Lubiprostone (Amitiza)
- MOA
- Chloride Channel Activator
- Contraindications
- Pregnancy
- Intestinal Obstruction
- Methylnaltrexone - Relistor
- Methylnaltrexone
- MOA
- Peripherally acting Mu antagonist
- Naldemedine - Symproic
- Naldemedine
Antimotility Drugs
- Lomotil
- Lomotil
- Slow intestinal transit
- Clostridium difficile
- Loperamide (Imodium)
- Loperamide
- intestinal muscles
- Contraindications
- Diphenoxylate
- Diphenoxylate
- Paregoric
- Paregoric
- Difenoxin
- Difenoxin
Absorbants
- Kaolin-Pectin
- Kaolin-Pectin
- MOA
- Polycarbophil
- Polycarbophil
- Attapulgite
- Attapulgite
- Cholestryamine
- Cholestryamine
- MOA
Octreotide (Sandostatin)
- MOA
- 5-HT3 Serotonergic Antagonist
- Indications
- Metastatic Vasoactive intestinal peptide-secreting tumor associated diarrhea
- ADR
- Bradycardia
- Hyperglycemia
Atropine
- Indications
- Blocks DUMBBeLSS
- Bradycardia
- Side Effects
- Skin Flushing
- Increased Temperature
- Dry Mouth
- Cycloplegia
- Disorientation
- Mydriasis
1 min
Traveler's Diarrhea Workup
- Prophylaxis
- Bismuth subsalicylate
- Treatment
- Oral Rehydration
- Fluoroquinolones
- Ciprofloxacin
- Azithromycin
- Rifaxamin
Irritable Bowel Syndrome (IBS) Assessment
- Abdominal Pain
- Relieved by Defecation
- Alternating Diarrhea and Constipation
- Fatigue
- Excessive Flatulence
- Sensation of Incomplete Evacuation
- Considerations
- Stressors
- Food Intolerances
- More Common in Women
- Rule Out Other Disorders
2 mins
Irritable Bowel Syndrome (IBS) Interventions
- Interventions
- Identify Triggers
- Increase Fiber Intake
- Probiotics
- Anticholinergics
- Tricyclic Antidepressants (TCAs)
- Loperamide
- Linaclotide
- Medications for Women
- Tegaserod (Zelnorm)
- Lubiprostone (Amitiza)
- Alosetron (Lotronex)
2 mins
Aminosalicylates
- Sulfasalazine (Azulfidine)
- Sulfasalazine
- Contraindications
- Salicylate Hypersensitivity or Sulfa Allergies
- Renal Impairmet
- ADR's
- Blood disorders
- Folic Acid absorption impaired
- Low Sperm counts
- Drug-induced Lupus
- Mesalamine
- Mesalamine
- Indications
- Suppository
- Delayed Release Formulations
- ADR's
- Better Tolerated than sulfasalazine
Azathioprine (Imuran)
- Mechanism
- Antimetabolite
- Prodrug of 6-mercaptopurine (6-MP)
- Inhibits Synthesis of Nucleic Acids
- Indications
- Autoimmune Disorders
- Kidney Transplantation
- Side Effects
- Myelosuppression
- Increased Toxicity with Allopurinol Use
- Pancreatitis
- Malignancy
3 mins
TNF-Alpha Inhibitor Drugs and Complications
- Etanercept
- Decoy TNF- Alpha receptor
- Anti-TNF- Alpha antibody
- Adalimumab
- Infliximab
- Complications
- Increased risk of infection
- Predispose to Tuberculosis (TB) reactivation
- Order Baseline PPD- skin test
- Quantiferon Gold In-Tube
- Order Chest X-Ray
2 mins
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