Lara Shared "Pharm 3 exam 1" - 16 Picmonics
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Pharm 3 exam 1
Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Inhibit H+/K+/ATPase
- Side Effects
- Hip fracture
- Pneumonia
2 mins
H2 Receptor Blocker
- "-tidine" Suffix
- Indications
- Gastroesophageal Reflux Disease (GERD)
- Peptic Ulcer
- Mechanism
- Block Histamine H2 Receptors
- Parietal Cells
52 secs
Cimetidine and Famotidine (H2 Receptor Blockers)
- -tidine Suffix
- Mechanism
- H2 Receptor Blocker
- Indications
- Suppress Gastric Acid Secretion
- Side Effects (All)
- Pneumonia
- Side Effects - Cimetidine
- Anti-androgen Effects
- CNS Changes
2 mins
Peptic Ulcer Disease Interventions
- Combination Drug Therapy
- Two Antibiotics
- Proton Pump Inhibitor (PPI)
- Decrease Acid Secretion
- Avoid NSAIDs
- Diet and Lifestyle Changes
1 min
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
Sucralfate (Carafate)
- Mechanism
- Creates Protective Barrier
- Indications
- GI Ulcers
- Side Effects
- Constipation
- Considerations
- Require Acidic Environment
- Give on Empty Stomach
- Oral Suspension Available
- May Decrease Absorption of Other Meds
2 mins
Metoclopramide
- Indications
- Antiemetic
- Promotility Agent
- Mechanism
- Increased Resting Tone
- Antagonist at D2 Receptor
- Side Effects
- Parkinsonian Symptoms
- Galactorrhea
- Contraindication
- Small Bowel Obstruction
- Parkinson's Disease
2 mins
Promethazine (Phenergan)
- Mechanism
- Histamine H1 Receptor Antagonist
- Weak Dopamine Antagonist
- Indications
- Nausea and Vomiting
- Motion Sickness
- Side Effects
- Respiratory Depression
- Sedation
- Anticholinergic Effects
- Extrapyramidal Symptoms
- Considerations
- Use Large Bore IV
- Monitor for Tissue Necrosis
2 mins
Anticholinergics
- B.O.AT.S Acronym
- Benztropine
- Parkinson's Disease
- Oxybutynin
- Decrease bladder spasms
- Atropine
- Mydriasis and Cycloplegia
- Scopolamine
- Motion Sickness
1 min
Imipenem
- Mechanism
- Resistant to Beta-Lactamases
- Broad Spectrum
- Indications
- Anaerobes
- Gram-Negative Rods
- Gram-Positive Cocci
- Must Administer with Cilastatin
- Cilastatin is Inhibitor of Renal Dehydropeptidase I
- Side Effects
- Diarrhea
- Skin Rash
- Seizures
- Considerations
- Meropenem
- Stable to Dehydropeptidase I
- Reduced Risk of Seizures (Non-Seizure Causing)
2 mins
Ribavirin
- Mechanism
- Hypermutation in RNA Viruses
- Inhibits Inosine Monophosphate Dehydrogenase
- Indications
- Hepatitis C
- Viral Hemorrhagic Fevers
- Respiratory Syncytial Virus (RSV)
- Side Effects
- Hemolytic Anemia
- Teratogen
1 min
Metronidazole
- Mechanism of Action
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Indications
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Side Effects
- Metallic taste
- Disulfiram like Reaction with Alcohol
2 mins
Vancomycin Mechanism
- Bacteriostatic and Bactericidal
- Gram-Positive
- Inhibits Cell Wall Mucopeptide
- Binds to D-ala D-ala
- Resistance with Change to D-ala D-lac
- Staphylococcus aureus
- Orally for Clostridium difficile
- Enterococci
2 mins
Vancomycin Side Effects & Toxicity
- Side Effects
- Thrombophlebitis
- Nephrotoxicity
- Ototoxicity
- Diffuse Flushing Called Red Man Syndrome
- Prevent with Antihistamine
- Prevent with Slow Infusion
2 mins
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
Azathioprine (Imuran)
- Mechanism
- Antimetabolite
- Prodrug of 6-mercaptopurine (6-MP)
- Inhibits Synthesis of Nucleic Acids
- Indications
- Autoimmune Disorders
- Kidney Transplantation
- Side Effects
- Myelosuppression
- Increased Toxicity with Allopurinol Use
- Pancreatitis
- Malignancy
3 mins
