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Pharm Exam 4
Aripiprazole (Abilify)
Mechanism
2nd Generation Atypical Antipsychotic
Indications
Schizophrenia
Bipolar Disorder
Depression
Side Effects
Headache
Dizziness
Nausea and Vomiting
Insomnia
Anxiety
Considerations
Low Risk of Extrapyramidal Symptoms
Lowest Risk of Weight Gain
2 mins
Benzodiazepine Antidote
Antidote
Flumazenil
40 secs
Benzodiazepine Intoxication Assessment
Drowsiness
Confusion
Respiratory Depression
Hypotension
Coma
Treatment
Flumazenil (Romazicon)
2 mins
Benztropine (Cogentin)
Mechanism
Anticholinergic
Indications
Parkinson's Disease
Acute Dystonia
Side Effects
Mydriasis
Dry Mouth
Urinary Retention
Tachycardia
Constipation
Psychosis
1 min
Buspirone (Buspar)
Mechanism
Increases Serotonin
Indications
Anxiety
Side Effects
Dizziness
Insomnia
Considerations
Delayed Effect
Safer with Alcohol than Other Anxiolytics
Low Side Effect Profile
Low Abuse Potential
1 min
Clozapine (Clozaril)
Mechanism
Atypical Antipsychotic
Indications
Schizophrenia
Levodopa-Induced Psychosis
Side Effects
Weight Gain
Hypersalivation (Sialorrhea)
Myocarditis
Agranulocytosis
Sedation
Orthostatic Hypotension
Constipation (Risk of Bowel Ileus)
Considerations
Weekly Lab Tests
2 mins
Diazepam (Valium)
Indications
Anxiety
Seizures and Status Epilepticus
Muscle Spasms
Alcohol Withdrawal
Side Effect/Assessment
Dizziness/Vision Changes
Confusion/Amnesia
Urinary Incontinence
Behavioral Changes
Respiratory Depression
Antidote
Flumazenil (Romazicon)
Nursing Considerations
Fall Precaution
Do Not Stop Abruptly
2 mins
Fluoxetine (Prozac)
Mechanism of Action
Inhibits Reuptake of Serotonin
Indications
Depression
Side Effects
Sexual Dysfunction
CNS Stimulation
Weight Changes
Serotonin Syndrome
Contraindications
No MAO-Is
No Anticoagulants / Antiplatelets
Considerations
Suicide Risk
Delayed Onset of Action
2 mins
Haloperidol (Haldol)
Mechanism
High Potency Antipsychotic
Indications
Migraine
Schizophrenia
Side Effects
Extrapyramidal Symptoms
Weight Gain
QT Prolongation
Restlessness
Considerations
Caution in Seizure Patients
Neuroleptic Malignant Syndrome
2 mins
High Potency Antipsychotic Drugs
High Potency Drugs
Fluphenazine
Trifluoperazine
Haloperidol
Pimozide
Side Effects
Extrapyramidal Symptoms
Short Term
Dystonia
Restlessness (Akathisia)
Torticollis
Long Term
Tardive Dyskinesia
Parkinson's-Like Symptoms
Neuroleptic Malignant Syndrome
3 mins
Lithium
Mechanism of Action
Mood Stabilizer
Unknown Mechanism
Indications
Bipolar Disorder
Side Effects
Nephrogenic Diabetes Insipidus
Hypothyroidism
Tremor
Heart Block
Contraindication
Pregnancy
Considerations
Monitor Plasma Levels
2 mins
Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
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