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Medicine (MD/DO)
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USMLE Step 1
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Infectious Disease
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Infectious Pulmonary Disorders

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Infectious Disease | Medicine (MD/DO) School Study Aid

Infectious Pulmonary Disorders
37 Picmonics to Learn | 1 hr 10 mins
Rhinovirus
Picornavirus
Cause of Common Cold
More than 100 Serologic Types
Destroyed by Stomach Acid
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32 secs
Picornavirus
Characteristics
Non-enveloped
RNA Virus
Icosahedral
Positive Sense
A large polypeptide cleaved by proteases
Viruses
Rhinovirus
Poliovirus
Coxsackievirus
Hepatitis A Virus
Echovirus
Aseptic meningitis
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1 min
Coronavirus
Characteristics
RNA Virus
Enveloped
Helical
SS Positive Linear
Symptoms
Common Cold
SARS (Severe Acute Respiratory Syndrome)
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1 min
Coxsackievirus
Characteristics
Picornavirus
Signs and Symptoms
Coxsackie A
Febrile Pharyngitis
Hand, Foot, and Mouth Disease
Most Common Cause of Aseptic Meningitis
Late Summer
Coxsackie B
Myocarditis
Dilated Cardiomyopathy
Type 1 Diabetes
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2 mins
Epstein Barr Virus Mononucleosis
Mononucleosis
Fever
Hepatomegaly
Splenomegaly
Pharyngitis
Posterior Cervical Lymphadenopathy
Atypical Lymphocytes
Heterophile Antibodies
Rash Develops if treated with Ampicillin
Hodgkin's Lymphoma
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2 mins
Adenovirus
Characteristics
Non-enveloped
Icosahedral
Linear
Double Stranded DNA
Signs and Symptoms
Pharyngitis
Conjunctivitis
Fever
Summer Swimming
Day Care Centers
Acute Hemorrhagic Cystitis
Pneumonia
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1 min
Streptococcus Pyogenes Disease
Pyogenic
Pyogenic
Pyogenic Pharyngitis
Impetigo
Cellulitis
Toxigenic
Toxic Shock-Like Syndrome
Scarlet Fever
Sandpaper Rash
Strawberry Tongue
Immunologic
Immunologic
Rheumatic Fever
Antibodies to M Protein
Acute Glomerulonephritis (Post Streptococcal Glomerulonephritis)
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2 mins
Moraxella catarrhalis
Characteristics
Gram-Negative
Diplococci
Oxidase-positive
Catalase-positive
Associated Infections
Otitis Media
Sinusitis
Chronic Obstructive Pulmonary Disease (COPD)
Bronchitis
Laryngitis
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2 mins
Chronic Bronchitis
Pathophysiology
Chronic Inflammation of Bronchi
Signs and Symptoms
Early-Onset Cyanosis
Blue Bloaters
Productive Cough
Wheezing
Chronic Obstructive Pulmonary Disease (COPD)
Late-Onset Dyspnea
Crackles
Diagnosis
Reid Index > 50%
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2 mins
Chronic Bronchitis Interventions
Tripod Position
Humidified Oxygen
Pursed Lip Breathing
Increase Fluid Intake
ABGs
Early Detection of Exacerbation
Considerations
Lowest O2 Therapy
Assisted Ventilation
Increased Infection Risk
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2 mins
Paramyxovirus
Characteristics
Enveloped
RNA Virus
Helical
SS Negative Linear
Nonsegmented
Surface Fusion Protein Causes Multinucleated Cells
Presentation
Measles
Mumps
Bronchiolitis in Babies
Viruses
Parainfluenza
Respiratory Syncytial Virus (RSV)
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2 mins
Bronchiectasis
Obstructive Lung Disease
Chronic Necrotizing Infection
Permanent Airway Dilation
Poor Ciliary Motility
Kartagener's Syndrome
Cystic Fibrosis
Allergic Bronchopulmonary Aspergillosis
Hemoptysis
Increased Sputum
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2 mins
Respiratory Syncytial Virus (RSV) Assessment
Mechanism
Viral Infection Affecting Epithelial Cells
Signs and Symptoms
Begins After a Upper Respiratory Infection
Copious Secretions
Coughing and Sneezing
Wheezing
Otitis Media or Conjunctivitis (Possible Ear or Eye Drainage)
Poor Feeding
Tachypnea
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2 mins
Influenza Virus
Characteristics
RNA Virus
Orthomyxovirus
Enveloped
Negative Sense
8 Segments
Helical
Hemagglutinin for Viral Entry
Neuraminidase for Virion Release
Genetic Shift
Reassortment of genome to cause major change
Genetic Drift
Minor Antigenic Mutations
Considerations
Reye Syndrome with Aspirin Use
Guillain-Barre Syndrome
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3 mins
Legionella Characteristics
Characteristics
Bacillus
Poor Gram Stain
Charcoal Yeast with Iron and Cysteine
Silver Stain
Water Sources
Smokers and Heavy Drinkers
Detect Antigen in Urine
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2 mins
Legionella Disease
Signs and Symptoms
High Fever
Diarrhea
Increased Liver Enzymes
Hyponatremia
Type IV Renal Tubular Acidosis
Severe Atypical Pneumonia
Pontiac Fever
Treatment
Fluoroquinolones
Macrolides
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2 mins
Mycoplasma Pneumoniae
Characteristics
No Cell Wall and No Gram Stain
Cholesterol Membrane
Eaton's Agar
Mulberry Colonies
Disease
Atypical pneumonia
Military Recruits
Cold IgM Autoimmune Hemolytic Anemia
Erythema Multiforme
Treatment
Tetracycline
Erythromycin
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2 mins
Streptococcus Pneumoniae Disease
Signs and Symptoms
Sickle Cell Anemia
Sepsis in Patients with Splenectomy
Rusty Sputum
MOPS
Meningitis
Otitis Media
Pneumonia
Sinusitis
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2 mins
Streptococcus Pneumoniae Characteristics
Characteristics
Gram-Positive
Diplococci
Lancet-Shaped
Catalase-Negative
Optochin-Sensitive
Bile Soluble
Alpha-Hemolytic
Polysaccharide Capsule
Positive Quellung Reaction
IgA Protease
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1 min
Coxiella burnetii
Characteristics
Gram Negative Bacteria
Intracellular
Aerosol Transmission
Affects Animal Handlers
Presentation
Q Fever
Flu-like Symptoms
Atypical Pneumonia
Hepatitis
Endocarditis
Diagnosis
Serology
Treatment
Doxycycline
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2 mins
Pneumocystis jirovecii
Fungi
AIDS/Immunocompromised
Fever
Hypoxemia
Bronchoalveolar Lavage
Biopsy
Methenamine Silver Stain
Saucer/cup shaped yeast forms
Diffuse interstitial pneumonia CXR
TMP-SMX
Start prophylaxis when CD4 drops under 200
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1 min
Mycobacterium Tuberculosis Characteristics
Characteristics
Mycolic Acid Cell Wall
Acid-fast
Carbolfuchsin Stain Red
Lowenstein-Jensen Agar
Serpentine Cord Factor
Primary TB
Primary TB
Caseating Granuloma
Ghon Focus
Hilar Lymph Nodes
Ghon Complex
Reactivation TB
Reactivation TB
Reactivation in Apex
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3 mins
Mycobacterium Tuberculosis Disease
CONSTITUTIONAL SYMPTOMS/PULMONARY TUBERCULOSIS
Fever
Night Sweats
Weight Loss
Hemoptysis
EXTRA-PULMONARY TUBERCULOSIS
Extrapulmonary Disease
Addison's Disease
CNS
Liver
Kidneys
GI
Bones
Pott's Disease
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3 mins
Tuberculosis Intervention
Hospital Care
Airborne Isolation
Drug Therapy
Combination Drug Therapy (RIPE)
6-12 Months
Considerations
DOT
BCG Vaccination
Medication Education
3 Negative Sputum Specimens
Infection Control
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2 mins
Ghon Complex
Calcified Focus of Infection
Hilar Lymph Nodes
Primary Tuberculosis
Typically in Children
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1 min
Tuberculosis Skin Mantoux Test (PPD)
Delayed Hypersensitivity (Cell Mediated Response)
Intradermal Injection
Read 48-72 hours
Positive Results
≥ 5 mm Induration
Immunosuppressed
≥ 10 mm Induration
High Risk Patients
≥ 15 mm Induration
Considerations
Chest X-Ray
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3 mins
Chlamydia
Mechanism
Chlamydia trachomatis
Assessment
May Be Asymptomatic
Dysuria
Epididymitis
Discharge
Dyspareunia
Interventions
Doxycycline
Azithromycin
No Intercourse for 1 Week
Treat Partners
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2 mins
Chlamydia Characteristics
Characteristics
Cannot Make ATP
Elementary Body Infects
Intraepithelial
Reticulate Body Replicates
Diagnosis
Cell Wall Lacks Muramic Acid
Giemsa Stain
Inclusion Bodies
Treatment
Doxycycline (Preferred)
Azithromycin
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2 mins
Chlamydia trachomatis
Characteristics
A to C
Trachoma
Follicular Conjunctivitis
Blindness
Africa
L1 to 3
Lymphogranuloma venereum
Buboes
Genital Ulcer
D to K
Urethritis and PID
Neonatal Pneumonia
Staccato Cough
Neonatal Conjunctivitis
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2 mins
Aspergillus fumigatus
Characteristics
Fungi
Monomorphic
Septate Hyphae
Branch at Acute Angles
Fruiting Bodies
Disease
Allergic Bronchopulmonary Aspergillosis (ABPA)
Eosinophilia
Increased IgE
Glucocorticoids +/- Azoles
Pulmonary Aspergillosis
TB Cavity
Lung Aspergilloma
Hemoptysis
Invasive Aspergillosis
AIDS/Immunocompromised
Chronic Granulomatous Disease
Hemorrhagic Infarction
Necrotizing Bronchopneumonia
Voriconazole +/- Caspofungin
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3 mins
Nocardia
Characteristics
Aerobic
Gram-Positive
Catalase-Positive
Urease-Positive
Acid Fast
Branching
Beaded Filament
AIDS/Immunocompromised
Soil
Signs and Symptoms
Lung Cavitation
Brain Abscess
Kidney Abscess
Treatment
TMP-SMX
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2 mins
Bacillus Anthracis (Anthrax) Characteristics
Characteristics
Gram-Positive
Spore-Forming
D-glutamate Polypeptide Capsule
Protective Antigen
Lethal Toxin
Edema Factor
Increased cAMP
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1 min
Bacillus Anthracis (Anthrax) Disease
Signs and Symptoms
Cutaneous
Painless Black Eschar (Necrotic Lesion)
Pulmonary
Mediastinal Widening
Rapidly Fatal
Woolsorter's Disease
Gastrointestinal
Consuming Anthrax-infected Meat
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2 mins
Rhinosinusitis Assessment
Pathology
Sinus Obstruction
Assessment
Nasal Drainage
Facial Pain
Lower Forehead
Cheeks
Nose
Retro-orbital
Fever
Persistent Symptoms
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2 mins
Atypical Pneumonia
CHARACTERISTICS
Diffuse Patchy Inflammation
Interstitial Pattern
"Walking Pneumonia"
Etiologies
Mycoplasma pneumoniae
Chlamydia pneumoniae
Legionella pneumophila
Adenovirus
Respiratory Syncytial Virus (RSV)
Cytomegalovirus (CMV)
Influenza
Presentation
Dry Cough
Treatment
Macrolides
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2 mins
Epiglottitis Assessment
Cause/Mechanism
Haemophilus Influenzae
Assessment
Drooling
Fever
Stridor
Restlessness
Dyspnea
Cough
Tripod Position
Considerations
Emergency Treatment
Do Not Examine Throat
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2 mins
Epiglottitis Interventions
Interventions
Maintain Airway
Upright/Sitting Position
Humidified Oxygen
Intubation/Tracheostomy Supplies At Bedside
IV Antibiotics
Decrease Anxiety
Considerations
NPO
Vaccine
Restrain to Prevent Extubation
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2 mins

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