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Pharmacology | Medicine (MD/DO) School Study Aid
Heart Failure Interventions
- Diagnostic Tests
- Echocardiogram
- Invasive Hemodynamic Monitoring
- Improve Gas Exchange
- High Fowler's Position
- Oxygen
- Advanced Airway
- Drugs and Devices
- Diuretics
- Beta Blockers
- Angiotensin II Receptor Blockers (ARBs)
- ACE Inhibitors
- Digoxin (Lanoxin)
- Pacemaker
2 mins
Nitroglycerin
- Indications
- Pulmonary Edema
- Angina
- Mechanism of Action
- Decreases Preload
- Releases NO in Blood
- Side Effects
- Hypotension
- Reflex Tachycardia
- Flushing
- Monday Disease
- Contraindications
- Viagra (Sildenafil)
2 mins
Digoxin Mechanism and Indication
- Direct inhibition of Na K ATPase
- Indirect inhibition of Na Ca exchanger
- Increase Ca in cell
- Positive Inotropy
- CHF
- Stimulates Vagus Nerve
- Decreased conduction at AV node
- Atrial Fibrillation
1 min
Acute Digoxin Toxicity
- Clinical Symptoms
- Hyperkalemia
- Cholinergic (Nausea, Vomiting, Diarrhea)
- Blurry Yellow Green Vision with Halo of Light
- Arrhythmia
- Bradycardia
- EKG Changes
- Prolonged PR interval
- Decreased QT
- Scooping on EKG
- T Wave Inversion
2 mins
Digoxin Toxicity Treatment
- Activated Charcoal
- Slowly Normalize K+
- Digibind (Anti-Digoxin Fab)
- Magnesium Sulfate
- Lidocaine
- Cardiac Pacing
2 mins
Beta-1 Agonists
- Dobutamine
- Heart Failure
- Cardiac Stress Test
- Isoproterenol
- Bradyarrhythmias
- Torsades de Pointes
58 secs
Selective Beta-1 Blockers
- Characteristics
- "-olol" Suffix
- Drug Names
- Beta-1 Selective
- Atenolol
- Esmolol
- Metoprolol
- Partial Beta agonists
- Acebutolol
1 min
Dobutamine
- Mechanism
- Beta-1 Agonist
- Inotropic
- Indications
- Heart Failure
- Side Effects
- Tachycardia
- Arrhythmias
- Considerations
- Closely Monitor Patients
- Other Meds May Increase Potency
1 min
Norepinephrine (Levophed)
- Mechanism of Action
- Alpha Agonist
- Beta-1 Agonist
- Indications
- Severe Hypotension
- Side Effect
- Decreases Renal Blood Flow
- Arrhythmias
- Hypertension
- Considerations
- Tissue Necrosis
- Last Resort Medication
2 mins
Epinephrine
- Mechanism of Action
- Alpha Agonist
- Beta Agonist
- Indications
- Hypotension
- Anaphylaxis
- Allergy
- Glaucoma
45 secs
Alpha Agonists
- -RINE suffix
- Norepinephrine
- Hypotension
- Phenylephrine
- Hypotension
- Congestion
- Ephedrine
- Congestion
- Urinary Incontinence
- Hypotension
- Epinephrine
- Anaphylaxis and Asthma
- Hypotension
1 min
Alpha-2 Agonists (Sympathoplegics)
- Indications
- Hypertension
- Renal disease
- Mechanism of Action
- Centrally acting Alpha-2 Agonist
- Drugs
- Clonidine
- Rebound Hypertension
- Alpha-Methyldopa
- Pregnancy
- Coombs (+) Hemolytic Anemia
- SLE Like Syndrome
2 mins
Mannitol (Osmitrol)
- Indications
- Increased Intracranial Pressure (ICP)
- Glaucoma
- Drug Overdose
- Mechanism of Action
- Osmotic diuretic
- Increased Urine Flow
- Side Effects
- Dehydration
- Contraindications
- Anuria
- CHF
2 mins
Milrinone and Amrinone
- Mechanism of Action
- Phosphodiesterase 3 Inhibitor
- Potentiates Beta Receptor Effects
- Inotrope
- Vasodilator
- Indication
- Acute Decompensated Heart Failure
- Side Effects
- Ventricular Arrhythmias
- Hypotension
2 mins
Sacubitril
- Indication
- Heart Failure
- Mechanism
- Neprilysin Inhibitor
- Side Effects
- Combine With Valsartan
- Hypotension
- Hyperkalemia
- Cough
- Dizziness
- Contraindication
- Avoid With Ace Inhibitors
2 mins
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