Stable Angina
- Chest Pain with Exertion
- Relieved within 15 Minutes
- ST Depression
- Nitroglycerin
- Up to 3 Doses q 5 Minutes
- Rest
- Antiplatelet Medication
- CABG
- Angioplasty
Unstable Angina
- Chest Pain with Rest or Exertion
- Limits ADLs
- > 15 Minutes
- Less Likely Relieved by Nitroglycerin
- ST Depression
- Fatigue
- Acute Coronary Syndrome (ACS) Treatment
- Emergency Treatment
Myocardial Infarction Assessment
- Substernal Chest Pain
- Crushing or Dull Sensation
- Arm, Jaw, and Neck
- > 20 Minutes
- Unrelieved by Nitro
- Palpitations
- Diaphoresis
- Fear of Impending Doom
- Nausea and Vomiting
- Shortness of Breath
- Monitor for Arrhythmias
Myocardial Infarction Diagnosis
- 12 Lead ECG
- ST Elevation
- Q Wave
- T Wave Inversion
- Troponin T and I
- CK-MB
- Early ECG
- Cardiac Stress Test
Myocardial Infarction Interventions
- Morphine
- Oxygen
- Nitrates
- Aspirin
- Thrombolytics (tPA)
- Cardiac Catheterization
- Stent Placement
- Angioplasty
- Coronary Artery Bypass Grafting (CABG)
- Decrease Modifiable Risk Factors
- Resuming Activity (Physical, Sexual)
Cardiac Catheterization
- Fluttering Sensation
- Contrast Media
- NPO 6-12 Hours
- Bed Rest
- Assess Circulation
- Assess for Bleeding
- Monitor Vital Signs
Cardiac Enzyme Evaluation: Troponin
- Cardiac Muscle Injury
- Detection in Blood: 4 Hours
- Peak: 24 - 36 Hours
- Return to Normal: 5 - 14 Days
- Most Specific for Cardiac Muscle
- Treat Aggressively
Cardiac Enzyme Evaluation: Creatine Kinase CK-MB
- Skeletal or Cardiac Muscle Injury
- Onset: 4-8 Hours
- Peak: 12-24 Hours
- Return to Normal: 2-3 Days
Cardiac Enzyme Evaluation: Myoglobin
- Skeletal or Cardiac Muscle Injury
- Onset: 1 - 4 Hours
- Peak: 12 Hours
- Return to Normal: 24 Hours
- Elevation After 24 Hours: Reinfarction
TIMI Score (Thrombolysis In Myocardial Infarction)
- Mortality Predictor
- Unstable Angina or NSTEMI
- 2 Week Risk of Death and Ischemic Events
- Age Greater or Equal to 65
- Markers Elevated
- EKG ST Changes (Greater or Equal to 0.5mm)
- Risk Factors for CAD (Coronary Artery Disease)
- Ischemia (2 Anginal Events in 24 Hours)
- Coronary Artery Disease (CAD)
- Aspirin Use in the Last 7 Days
Evolution of Myocardial Infarction and Complications
- Arrhythmia
- Fibrinous Pericarditis
- Papillary Muscle Rupture
- Interventricular Septum Rupture
- Ventricular Pseudoaneurysm
- Ventricular Free Wall Rupture
- True Ventricular Aneurysm
- Dressler Syndrome
- Left Ventricular Failure
12 Lead Contiguous Leads - Anterior Wall MI
- Lead V3
- Lead V4
- Left Anterior Descending (LAD)
12 Lead Contiguous Leads - Septal Wall MI
- Lead V1
- Lead V2
- Left Anterior Descending (LAD)
12 Lead Contiguous Leads - Inferior Wall MI
- Lead II
- Lead III
- Lead aVF
- Right Coronary Artery (RCA)
12 Lead Contiguous Leads - Lateral Wall MI
- Lead I
- Lead aVL
- Lead V5
- Lead V6
- Circumflex
Brugada Syndrome
- Defective Myocardial Sodium Channels
- Predominance in Asian Males
- Autosomal Dominant
- Pseudo-Right Bundle Branch Block Pattern
- Persistent ST Elevations in Leads V1-V2
- Risk of VTACH and Sudden Cardiac Death
- Syncope
- ICD
- Antiarrhythmics
Ischemia and Vulnerable Tissues
- Brain
- MCA-ACA and MCA-PCA Interface
- Heart
- Subendocardium of Left Ventricle
- Kidney
- Proximal Tubule
- Thick Ascending Limbs of the Loop of Henle
- Liver
- Central Vein
- Colon
- Splenic Flexure
- Rectosigmoid Junction