Vitamin D Metabolism/Mechanism
- Ergocalciferol (Vitamin D2)
- Plant Sources
- Cholecalciferol (Vitamin D3)
- Sunlight Conversion in Skin
- 7-Dehydrocholesterol
- Liver Hydroxylation
- 25-(OH) D (25-hydroxyvitamin D)
- Storage Form
- Kidney Hydroxylation
- 1,25-(OH)2 D (1,25-dihydroxyvitamin D)
- Active Form Calcitriol
- Absorbs Calcium and Phosphorus in Intestine
Vitamin D Deficiency
- Rickets in children
- Bending bones
- Rachitic rosary
- Breast milk has decreased vitamin D
- Osteomalacia in adults
- Tetany from Hypocalcemia
Vitamin D Toxicity
- Kidney Stones
- Metastatic Calcification of the Kidney
- Loss of Appetite
- Abdominal Pain
- Sarcoidosis
Ergocalciferol (Vitamin D2)
- Vitamin D2
- Hypoparathyroidism
- Rickets
- Hypophosphatemia
- Fatigue
- Constipation
- Hypercalcemia
- Kidney Stones
Cholecalciferol (Vitamin D3)
- Vitamin D3
- Dietary Supplement
- Vitamin D Deficiency
- Fatigue
- Constipation
- Hypercalcemia
- Kidney Stones
- More Effective Than Ergocalciferol
- Hypervitaminosis D
Vitamin E (Alpha-tocopherol)
- Antioxidant
- Fat Malabsorption Syndrome
- Alpha-TTP Deficiency
- Bleeding
- Increased Risk Hemorrhagic Stroke
- Limit Doses < 200 IU per Day
- Nuts and Whole Grains
- Vegetable Oils
Vitamin E Deficiency
- Antioxidant
- Protects Erythrocytes
- Protects from Free Radical Damage
- Hemolytic Anemia
- Posterior Column
- Spinocerebellar Tract
Vitamin K Deficiency
- Bleeding
- Neonatal Hemorrhage with Increased PT and aPTT
- Liver Disease
- Chronic Antibiotic Use
- Vitamin K Antagonists
- Malabsorption
- Dietary Deficiencies
- Normal Bleeding Time
- Increased PT and PTT
- Neonatal Vitamin K Injection