Epstein Barr Virus
- Herpesvirus 4
- Double Stranded DNA
- Linear
- Enveloped
- Infectious Mononucleosis
- Virus Attaches to CD21 in B Cells
- Nasopharyngeal Carcinoma
- Burkitt's Lymphoma
- Hodgkin's Lymphoma
Hepatitis B Virus Characteristics
- Hepadnavirus
- Enveloped
- Circular
- Partially Double-stranded DNA
- Has Reverse Transcriptase
- IV Drug Use
- Sex
- Maternal Fetal Routes
- 3 Month Incubation Period
Hepatitis C
- Enveloped
- RNA Virus
- Flavivirus
- Icosahedral
- SS positive Linear
- Most Cases are Due to IV Drug Use
- Turns to Chronic Hepatitis in Over 70% of Cases
- Cirrhosis
- Hepatocellular Carcinoma
- Most Common Indication for Liver Transplantation
- Associated With Type I MPGN
- Porphyria Cutanea Tarda
Kaposi Sarcoma
- Malignant Vascular Tumor
- Human Herpesvirus Type 8 (HHV-8)
- AIDS/Immunocompromised
- CD4+ < 500
- Multifocal Purple Lesions
- Skin
- Mucous Membranes
- Visceral Organs
- Spindle-shaped Cells
- Observation
- Chemotherapy
- Treat Underlying Disorder
Human Papillomavirus (HPV)
- Non-enveloped
- Circular
- Double Stranded DNA
- Warts 1, 2, 6, 11
- Condyloma acuminata
- Type 16, 18
- Cervical Carcinoma
- Penile Carcinoma
- AIDS/Immunocompromised
- Worsened by Smoking
- Koilocytic change in squamous epithelium
- Pyknotic Nuclei Surrounded by Clear Halo
- Vaccine Available
Helicobacter Pylori
- Gram-Negative
- Bacilli
- Curved
- Polar Flagellum
- Catalase-Positive
- Oxidase-Positive
- Gastric and Duodenal Ulcers
- Ammonia
- Neutral Environment
- Gastric Adenocarcinoma
- MALT lymphoma
- Serology IgG antibody
- Stool Antigen
- Urease Positive Breath Test
- Biopsy
- 2 ABX and PPI
Adult T Cell Lymphoma
- Caused by HTLV 1
- Japan, West Africa, Caribbean
- Present with cutaneous lesions
- Aggressive
Clonorchis Sinensis
- Trematode (Fluke)
- Undercooked Fish
- Biliary Tract Inflammation
- Pigmented Gallstones
- Associated with Cholangiocarcinoma
- Praziquantel
Schistosoma
- Trematode (Fluke)
- Snail-infested Water
- Intense Immune Response
- Intestinal Disease
- Hepatosplenic Granuloma
- Squamous Cell Cancer of the Bladder
- Parasitic Antigens via ELISA
- Praziquantel
Squamous Cell Carcinoma of the Bladder Clinical Features
- Smoking
- Chronic Cystitis
- Schistosoma
- Chronic Nephrolithiasis
- Painless Hematuria
- Urinary Frequency and Urgency
Paget's Disease of Bone
- Men > Age 40
- Increased Osteoblast and Osteoclast activity
- Mosaic Pattern
- Increased Skull Diameter
- Hearing Loss
- Fractures
- Bone Ache and Joint Pain
- High Output Heart Failure
- Bone Scan
- Normal Parathyroid hormone (PTH) and Calcium
- Elevated ALP
- Bisphosphonate
- Calcitonin
Complete Hydatidiform Mole
- Gestational Trophoblastic Disease
- Fertilization of Enucleated Egg
- Diploid Fetal Karyotypes
- Hydropic Chorionic Villi
- Vaginal Bleeding
- Preeclampsia
- Increased Beta hCG
- "Snowstorm" / "Bunch of Grapes" Appearance
- Theca Lutein Cysts
- Dilation and Curettage (D&C)
- Methotrexate
- Increased Risk of Choriocarcinoma
Hydatidiform Mole (Molar Pregnancy)
- Abnormal Fertilization
- Symptoms of Pregnancy
- Elevated hCG
- Vaginal Bleeding
- Inappropriate Uterine Growth
- No Fetal Heart Rate (FHR)
- Dilation and Curettage (D&C)
- Emotional Support
- No Pregnancy 1 Year
- Hysterectomy
Choriocarcinoma
- Germ-cell tumor
- Trophoblastic tissue
- Hematogenous spread to lungs
- Malignant
- Theca-lutein cysts
- Hydatidiform Mole
- hCG
Ovarian Cystadenocarcinoma
- Non-germ Cell Tumor
- Mucinous
- Peritoneal Spread
- Serous
- Psammoma Bodies
- Bilateral
- Malignant
- Stromal Invasion
- CA 125
- BRCA-1 and Lynch Syndrome
Carcinoid Syndrome
- Neuroendocrine Cells
- Serotonin
- Appendix
- Chromogranin A
- Neuron Specific Enolase
- Dense Core Bodies on EM
- Symptoms When Metastasize to Liver
- Flushing
- Wheezing
- Right Heart Murmur
- Diarrhea
Dysgerminoma
- Germ-cell tumor
- Most Common Malignant Germ Cell Tumor
- Uniform Cells
- Fried Egg Cells
- hCG
- LDH
- Seminoma-like
- Turner Syndrome
Prostate Adenocarcinoma Characteristics and Presentation
- Most Common Cancer in Men
- Screening Test if Suspicious
- Prostate Specific Antigen (PSA)
- Peripheral Zone
- African American
- Advanced Age
- Usually Asymptomatic
- Terminal Hematuria
- Urinary Retention or Incontinence
- Lower Back Pain
Partial Hydatidiform Mole
- Gestational Trophoblastic Disease
- Dual Fertilization of Haploid Egg
- Triploid Fetal Karyotypes
- Hydropic Chorionic Villi
- Vaginal Bleeding
- Increased Beta hCG
- Fetal Structures
- Dilation and Curettage (D&C)
- Methotrexate