Microcytic Anemia Causes
- MCV < 80
- Thalassemias
- Chronic Disease or Illness
- Lead Toxicity
- Late Iron Deficiency
- Sideroblastic Anemia
Normocytic Nonhemolytic Anemia Causes
- MCV 80-100
- Anemia of Chronic Disease/Inflammation
- Aplastic Anemia
- Chronic Kidney Disease
- Early Iron Deficiency
Normocytic Hemolytic Anemia Causes
- Hereditary Spherocytosis
- RBC Enzyme Deficiency
- Hemoglobin C Defect
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Sickle Cell Anemia
- Autoimmune
- Microangiopathic
- Mechanical Destruction
- Prosthetic Cardiac Valves
- Infection
- Snake Venom
Macrocytic Anemia Causes
- MCV > 100
- B12 Deficiency
- Folate Deficiency
- Orotic Aciduria
- Alcoholism
- Liver Disease
- Reticulocytosis
Iron Deficiency Anemia
- Malnutrition/Malabsorption
- Hemorrhage
- Microcytic, Hypochromic Anemia
- Decreased Heme Synthesis
- Decreased Reticulocytes
- Decreased Ferritin
- Increased Red Cell Distribution Width (RDW)
- Poikilocytosis
- Anisocytosis
- Increased Central Pallor
Hemochromatosis Pathophysiology
- Hemosiderin Deposition
- Autosomal Recessive
- HLA-A3
- Secondary to Transfusion Therapy
- Increase Iron
- Increase Ferritin
- Increased Transferrin Saturation