Ace Your Pathoma: Fundamentals of Pathology (2018) Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Medicine (MD/DO) Students
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Pathoma: Fundamentals of Pathology (2018) | Medicine (MD/DO) School Study Aid
Diabetic Ketoacidosis (DKA) Signs and Symptoms
- Kussmaul respirations
- Dehydration
- Abdominal Pain
- Nausea/vomiting
- Psychosis
- Fruity breath Odor
1 min
Diabetic Ketoacidosis (DKA) Diagnosis and Labs
- Diagnosis
- Blood glucose Increased > 250 mg/dL
- Anion gap metabolic acidosis
- Decreased pH < 7.3
- Decreased serum bicarbonate < 18
- Plasma ketones
- Other Labs
- Hyperkalemia
1 min
Diabetic Ketoacidosis (DKA) Treatment
- Initial Management
- IV Normal Saline
- Regular Insulin Drip
- Subsequent Management (correction of electrolytes)
- Potassium (K+)
- Glucose
- Treat Underlying Cause
- Monitoring
- Venous pH
- Serum Bicarbonate (HCO3)
1 min
Diabetes Assessment
- Assessment Type 1
- Juvenile Onset
- Absent Insulin Production
- Ketosis Prone
- Assessment Type 2
- Adult Onset
- Insulin Resistance
- Obesity
- Gestational Diabetes
- Onset During Pregnancy
- Glucose Intolerance
- Complications
- Retinopathy
- Peripheral Vascular Disease
- Nephropathy
- Neuropathy
2 mins
Diabetes Interventions
- Early Diagnosis
- Insulin
- Oral Hypoglycemics
- Glucose Monitoring
- Routine Exercise
- Diabetic Diet
- Monitor for Complications
- Insulin Therapy
- Diabetic Ketoacidosis (DKA)
2 mins
Diabetes Education
- Self-Monitoring (Blood Glucose)
- SubQ Injection Technique
- Lifestyle Changes
- Symptoms of Hyperglycemia and Hypoglycemia
- Sick Day Care
- Foot Care
- Exercise Therapy
- Medication
1 min
Gestational Diabetes
- Signs and Symptoms
- Usually Asymptomatic
- Fetal Macrosomia
- Polyhydramnios
- Diagnosis
- Glucose Intolerance After 24 Weeks Gestation
- 3-hr 100g Glucose Tolerance Test
- Treatment
- Diet and Exercise
- Close Glucose Monitoring
- Insulin
- Ultrasound (or Nonstress Test (NST))
- Delivery
2 mins
Nonproliferative Diabetic Retinopathy
- Characteristics
- Increased Capillary Permeability and Leakage
- Often Asymptomatic
- Fundoscopic Findings
- Retinal Microaneurysms
- Flame-shaped Hemorrhages
- Cotton Wool Spots
- Hard Exudates
- Macular Edema
- Management
- Treat Diabetes
- Laser Photocoagulation
- Bevacizumab
3 mins
Proliferative Diabetic Retinopathy
- Characteristics
- Angiogenesis
- Increased VEGF
- Asymptomatic Until Late-stage
- Fundoscopic Findings
- Vitreous Hemorrhage
- Retinal Detachment
- Glaucoma
- Findings of Nonproliferative Diabetic Retinopathy
- Management
- Laser Photocoagulation
- Surgery
- Bevacizumab
2 mins
Diabetic Glomerulonephropathy
- Pathophysiology
- Nonenzymatic Glycosylation of Glomerular Basement Membrane
- Nonenzymatic Glycosylation of Arterioles
- Hyperfiltration
- Increased GFR
- Histological Findings
- Hyaline Arteriolosclerosis
- Mesangial Expansion
- Type IV Collagen Deposition
- Kimmelstiel Wilson Lesions
- Presentation
- Nephrotic
2 mins
MEN 1 (Multiple Endocrine Neoplasia)
- Pathophysiology
- Autosomal Dominant
- Menin Mutation (Tumor Suppression Gene)
- Chromosome 11
- Signs and Symptoms
- Pancreatic Endocrine Tumors
- Pituitary Tumors
- Parathyroid Adenomas
2 mins
MEN 2A (Multiple Endocrine Neoplasia)
- Pathophysiology
- Autosomal Dominant
- RET Gene
- Signs and Symptoms
- Medullary Thyroid carcinoma
- Calcitonin
- Parathyroid
- Pheochromocytoma
45 secs
MEN 2B (Multiple Endocrine Neoplasia)
- Pathophysiology
- RET Gene
- Autosomal Dominant
- Signs and Symptoms
- Medullary Thyroid Carcinoma
- Pheochromocytoma
- Mucosal Neuromas
- Marfanoid Body Habitus
2 mins
Insulinoma
- Characteristics
- Pancreatic Neuroendocrine Tumor
- Benign
- Associated with MEN-1
- Clinical Features
- Whipple Triad
- Symptoms of Hypoglycemia
- Hypoglycemia During Episode
- Relief with Glucose
- Diagnosis
- Increased C-peptide
- Management
- Surgery
- Octreotide
- Diazoxide
2 mins
Zollinger-Ellison Syndrome Disease
- Pathophysiology
- Gastrin-Secreting Tumor
- Increased Gastric Acid
- Recurrent Peptic Ulcers
- MEN Type 1
- Symptoms
- Abdominal Pain
- Heartburn (Pyrosis)
- Diarrhea
3 mins
Zollinger-Ellison Syndrome Diagnosis and Treatment
- Diagnosis
- Gastrin > 1000 pg/mL
- Positive Secretin Stimulation Test
- Treatment
- High-Dose PPI
- Octreotide
- Surgical Resection
3 mins
Somatostatinoma
- Characteristics
- Pancreatic Neuroendocrine Tumor
- Originates from Delta Cells
- Clinical Features
- Steatorrhea
- Gallstones
- Hyperglycemia
- Diagnosis
- Increased Somatostatin
- Abdominal CT or MRI
- Management
- Octreotide
- Surgical Resection
- Chemotherapy
2 mins
VIPoma
- Characteristics
- Pancreatic Neuroendocrine Tumor
- Secretes Vasoactive Intestinal Polypeptide (VIP)
- Clinical Features
- GI Distress
- Watery Diarrhea
- Hypokalemia
- Achlorhydria
- Management
- Octreotide
- Surgical Resection
- Associations
- Multiple Endocrine Neoplasia Type 1 (MEN 1)
2 mins
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