Urinary Excretory Anatomy
- Renal Medulla
- Renal Cortex
- Nephron
- Bowman's Capsule
- Glomerulus
- Proximal Tubule
- Loop of Henle
- Distal Tubule
- Collecting Duct
- Ureter
- Urinary Bladder
- Urethra
Renal Corpuscle
- Arterioles
- Glomerulus
- Capillaries
- Fenestrations
- Plasma Solutes and Other Small Molecules Become Ultrafiltrate
- Bowman's Capsule Encapsulates Glomerulus
Collecting Duct
- Na+ Reabsorption
- Vasopressin Causes Water reabsorption
- Concentrates Filtrate
Proximal Tubule
- Na+ Reabsorbed Via Active Transport
- Water Follows Na+
- Most Of Glucose Reabsorbed
- Most Of Amino Acids Reabsorbed
- Bicarbonate Exchanged For H+
- Drugs and Toxins Excreted
- Filtrate Osmolarity Same As Plasma
- Leads To Loop Of Henle
Loop of Henle
- Descending Limb
- Water Follows Na+
- Medullary Hypertonicity
- Increased Water Reabsorption
- Vasa Recta
- Na+ Reabsorbed Via Active Transport
- Ascending Limb
- Reabsorbs Na+, K+, Cl-
- Decreased Concentration of Filtrate
- Impermeable to Water
- Distal Tubule
Distal Tubule
- Hormonally Regulated
- Aldosterone Causes Na+ Reabsorption
- Na+ Reabsorbed Via Active Transport
- Water follows Na+
- Early Distal Tubule is Impermeable to Water
- Parathyroid Hormone Causes Ca2+ Reabsorption
- Leads to Collecting Duct
Syndrome Of Inappropriate Antidiuretic Hormone (SIADH)
- Hypersecretion of ADH
- Increased Sensitivity to ADH
- Serum Hypoosmolality
- Coma and Seizure
- Dilutional Hyponatremia
- Cramps and Tremors
- Euvolemia
- Change in LOC
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Nonpharmacologic Interventions
- Monitor Serum and Urine Osmolality
- IandOs with Daily Weights
- Restrict Fluid Intake
- Monitor Cardiovascular and Neurological Status
- Seizure Precautions
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions
- Diuretics
- Hypertonic IV Fluids
- Demeclocycline
- Tolvaptan and Conivaptan
Adrenal Gland (Basic)
- Adrenal Cortex
- RAAS Stimulates Aldosterone
- CRF (CRH) acts on Anterior Pituitary Gland to Release ACTH
- Cortisol Released
- Androgens Released
- Adrenal Medulla
- Epinephrine & Norepinephrine
Adrenal Gland (Advanced)
- Adrenal Cortex
- Zona Glomerulosa
- Aldosterone
- Zona Fasciculata
- Cortisol
- Zona Reticularis
- Androgens
- Adrenal Medulla
- Chromaffin Cells
- Epinephrine & Norepinephrine
Creatinine Lab Values
- Measures Renal Function
- 0.6 - 1.3 mg/dL
BUN (Blood Urea Nitrogen) Lab Values
Urine Specific Gravity Lab Value
Dialysis
- Hemodialysis
- Rapid Shifts of Fluid and Electrolytes
- Disequilibrium Syndrome
- Hypotension
- NO BP IN ARM with Shunt or Fistula
- Assess for Thrill and Bruit
- Peritoneal Dialysis
- Slow Process
- Peritonitis
- Loss of Protein
- Hyperglycemia
Renal Calculi Assessment
- Hypercalcemia (Most Commonly)
- Flank Pain
- Radiates Toward Bladder
- Renal Colic
- Urinary Tract Infection
- Urinary Retention
- Hematuria
- Stone Recurrence
Renal Calculi Interventions
- Increase Fluid Intake
- Opioids
- NSAIDs
- Antibiotics
- Lithotripsy
- Surgical Stone Removal
- Identify Type CT-KUB
- Low Sodium Diet
Chronic Kidney Disease Early Symptoms Assessment
- GFR < 60mL/min
- Accumulation of Waste Products
- General Malaise
- Hypertension
- Proteinuria
- Hyperkalemia
- Mineral and Bone Disorders
- Neuropathy
Chronic Kidney Disease Late Symptoms Assessment
- Metabolic Acidosis
- Severe Uremia
- Arrhythmias
- Edema
- CNS Depression
- Anemia
- Oliguria
- Pruritus
- End Stage Renal Disease (ESRD)
- GFR < 15mL/min
Chronic Kidney Disease Interventions
- Daily Weights
- Strict I/O
- Renal Diet
- Strict Medication Regimen
- Erythropoietin
- Manage Hyperkalemia
- Manage CKD-MBD
- Dialysis
- Kidney Transplant
Iron Deficiency Anemia
- Malnutrition/Malabsorption
- Hemorrhage
- Microcytic, Hypochromic Anemia
- Decreased Heme Synthesis
- Decreased Reticulocytes
- Decreased Ferritin
- Increased Red Cell Distribution Width (RDW)
- Poikilocytosis
- Anisocytosis
- Increased Central Pallor
Nephrotic Syndrome
- Massive Proteinuria > 3.5g per Day
- Edema
- Increased risk of infection
- Thromboembolism
- Hyperlipidemia
- Fatty casts
Hyperkalemia
- > 5.0 mEq/L K+
- Abdominal Cramps
- Muscle Weakness
- Diarrhea
- Arrhythmia
- Tall, Peaked T Waves
- IV Calcium
- Infusion of Glucose and Insulin
- Loop or Thiazide Diuretics
- Kayexalate
- Dialysis
- Prevention Education
Hypermagnesemia
- Flushing
- Lethargy
- Muscle Weakness
- Decreased Deep Tendon Reflexes (DTRs)
- Decreased Respirations
- Bradycardia
- Hypotension
- Dialysis
- IV Calcium Gluconate
- Diuretics
- Avoid Antacids and Laxatives containing Mg2+
Hypocalcemia
- Muscle Spasms
- < 8.5 mg/dL Ca2+
- Decreased Bone Density
- Tetany
- Chvostek's Sign
- Trousseau's Sign
- Increased DTR
- ECG Changes
- QT Prolongation
- Oral and IV Replacement of Ca2+
- Seizure Precautions
Metabolic Acidosis Assessment
- Decreased pH < 7.35
- Decreased HCO3 < 22
- Abdominal Pain
- CNS Depression
- Coma
- Hypotension
- Arrhythmias
- Increased Respirations
- Kussmaul Respirations
- Flushed, Warm, Dry Skin
- Muscle Weakness
Metabolic Acidosis Interventions
- Raise Plasma pH > 7.20
- Treat Underlying Cause
- Sodium Bicarbonate
- Follow ABGs
- Continuously Monitor Patient
Types of Shock
- Hypovolemic
- Depleted Volume
- Cardiogenic
- Pump Failure
- Obstructive
- Indirect Pump Failure
- Distributive
- Lost Vascular Tone
- Neurogenic
- Anaphylactic
- Septic
Pulmonary Embolism Assessment
- Shortness of Breath (SOB)
- Pleuritic Chest Pain
- Tachypnea
- Hemoptysis
- Hypoxemia
- Sudden Death
Pulmonary Embolism Causes
- FAT BAT Mnemonic
- Fat
- Air
- Deep Vein Thrombosis (DVT)
- Bacteria
- Amniotic Fluid
- Tumor
- Hypercoagulable
- Central Venous Lines
- Immobilized
Kidney Transplant
- End Stage Renal Disease (ESRD)
- Selective Candidacy
- Close Compatibility
- Immunosuppressants
- Monitor for Rejection
- Monitor for Infection
- Monitor Urine Output
Pyelonephritis Assessment
- Ascending Urethral Bacteria
- Dysuria
- Fever
- Fatigue
- Flank Pain
- Costovertebral Tenderness
- Nausea and Vomiting
Pyelonephritis Interventions
- Urinalysis
- NSAIDs
- Antibiotics
- Increase Fluid Intake
- Avoid Catheterization
- Urosepsis
Urinary Tract Infection Symptoms
- More Common in Elderly
- Most Common in Females and Babies
- Change in LOC
- Dehydration
- Fever
- Urgency
- Urethral Infection
- Burning
- Smelly Urine
- Dark Cloudy Urine
- Frequency of Urination
Urinary Tract Infection Prevention and Treatment
- Shower after Sex
- Urinate after Sex
- Wipe front to Back
- I and Os with Daily Weights
- Increase Water Intake
- Antibiotics
- Avoid Caffeine
- Dr Appointment in 2 Weeks
- Void every 2 - 4 hours
Prostatitis
- Chronic Bacterial Prostatitis
- Acute Bacterial Prostatitis
- Sexually Transmitted Organisms
- E. Coli Infection
- Flu-Like Symptoms
- Perineal Pain
- Dysuria
- Sexual Dysfunction
- Recurrent UTIs
- Urinalysis
- Tender Boggy Prostate
- Antibiotics
- Chronic Prostatitis
Benign Prostatic Hyperplasia (BPH) Assessment
- Men Over 50
- Enlarged Prostate Gland
- Urinary Retention
- Weak Urine Stream
- Frequency
- Urgency
- Nocturia
Benign Prostatic Hyperplasia (BPH) Interventions
- Timed Voiding
- Decreased Caffeine Intake
- Catheterization
- Finasteride (Proscar)
- Tamsulosin (Flomax)
- TURP Procedure
- Open Prostatectomy
- Continuous Bladder Irrigation (CBI)
Benign Prostatic Hyperplasia (BPH) Diagnosis and Treatment
- Digital Rectal Exam
- Urinalysis to Detect Infection or Blood
- Alpha-1 Antagonists
- Tamsulosin
- 5 Alpha Reductase Inhibitors
- Finasteride
- TURP (Transurethral Resection of Prostate)