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Family Nurse Practitioner Certification Intensive Review 3rd Edition, Leik, 2018/
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Family Nurse Practitioner Certification Intensive Review 3rd Edition, Leik, 2018 | Nurse Practitioner (NP) School Study Aid
Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Inhibit H+/K+/ATPase
- Side Effects
- Hip fracture
- Pneumonia
2 mins
Vitamin K
- Sources
- Dark Green Leafy Vegetables
- Synthesized by Intestinal Flora
- Mechanism
- Activated by Epoxide Reductase
- Gamma Carboxylation of Glutamate
- Activation of Clotting Factors II, VII, IX, X, Protein C and S
- Considerations
- Deficiency with Broad Spectrum Antibiotics
- Neonatal Hemorrhage with Increased PT and aPTT
- Warfarin is a Vitamin K Antagonist
4 mins
Warfarin
- Mechanism of Action
- Interferes with Vitamin K-dependent Clotting Factors
- Extrinsic Pathway
- Bridge with Heparin
- Indications
- Chronic Anticoagulation
- Side Effects
- Bleeding
- Necrosis
- Cytochrome P450
- Contraindications
- Pregnancy
- Antidote
- FFP + Vitamin K
2 mins
Pioglitazone (Thiazolidinediones)
- -glitazones Suffix
- Mechanism
- Binds PPAR-Gamma
- Decreases Insulin Resistance
- Indications
- Type 2 Diabetes
- Side Effects
- Weight Gain
- Heart Failure
- Myalgia
- Hypoglycemia
- Upper Respiratory Infection
- Considerations
- Increased Risk of Bladder Cancer
- Increased Fracture Risk in Women
- Monitor Liver Enzymes
2 mins
Atypical Antipsychotics
- Indications
- Schizophrenia
- Mechanism of Action
- Unknown Mechanism
- Side Effects
- Seizures
- Prolonged QT Interval
- Agranulocytosis
- Weight Gain
- Fewer Extrapyramidal Side Effects
- Fewer Anticholinergic Side Effects
2 mins
Risperidone (Risperdal)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Side Effects
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Considerations
- Intramuscular Long Acting (Depot) Form
2 mins
Metabolic Syndrome
- Assessment
- Dyslipidemia
- Central Obesity
- Insulin Resistance
- Hypertension
- Increased C-Reactive Protein (CRP)
- Increased Fibrinogen
- Considerations
- Increased Risk Cardiovascular Disease
1 min
Alendronate (Fosamax)
- Mechanism
- Inhibits Osteoclasts
- Indications
- Osteoporosis
- Paget's Disease
- Side Effects
- Esophageal Ulcers
- Musculoskeletal Pain
- Vision Changes
- Atrial Fibrillation
- Osteonecrosis of the Jaw
- Considerations
- Take on Empty Stomach
- Remain Upright
2 mins
Gastroesophageal Reflux Disease (GERD) Assessment
- Pathophysiology
- Relaxed Lower Esophageal Sphincter
- Signs and Symptoms
- Dyspepsia (Indigestion)
- Belching
- Nighttime Coughing
- Dysphagia
- Epigastric Pain
- Regurgitation
- Heartburn (Pyrosis)
- Globus
2 mins
Statins
- Rhabdomyolysis
- Hepatotoxicity
- HMG-CoA reductase inhibitors
- Decrease LDL
- Decrease Triglycerides
- Increase HDL
2 mins
Atorvastatin (Lipitor)
- Characteristics
- -statin Suffix
- Mechanism
- HMG-CoA Reductase Inhibitors
- Indications
- High Cholesterol
- Side Effects
- Hepatotoxicity
- Rash
- Rhabdomyolysis
- Myopathy
- Considerations
- Monitor Liver Enzymes
- Administer at Bedtime
- Avoid Grapefruit
2 mins
Clindamycin
- Mechanism of Action
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Blocks Translocation
- Indications
- Anaerobic Infections above the Diaphragm
- Aspiration Pneumonia
- Lung Abscess
- Side Effects
- Can Cause Pseudomembranous Colitis
1 min
