Nurse Practitioner Certification Examination and Practice Preparation 4th Edition, Fitzgerald, 2015 | Nurse Practitioner (NP) School Study Aid
Neomycin Sulfate
- Aminoglycoside Antibiotic
- Topical Infection
- Intestinal Surgery Prophylaxis
- Ototoxicity
- Nephrotoxicity
- Rash
- Blood Dyscrasias
- GI Superinfection
Tetracycline Mechanism
- Binds to 30 S to Prevent Attachment of Aminoacyl tRNA
- Limited CNS Penetration
- Divalent Cations Inhibit Absorption
- Must Not Take with Milk, Antacids, Iron
Tetracycline Drug Names and Indications
- Demeclocycline
- Minocycline
- Doxycycline
- Fecally Eliminated
- Can be Used in Renal Failure
- Antidiuretic Hormone Antagonist
- Chlamydia
- Rickettsia
- Borrelia burgdorferi
- Helicobacter Pylori
- Mycoplasma Pneumonia
Tetracycline Toxicities
- Inhibition of Bone Growth in Children
- Teratogen
- Discoloration of Teeth
- Photosensitivity
- GI Distress
Clindamycin
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Blocks Translocation
- Anaerobic Infections above the Diaphragm
- Aspiration Pneumonia
- Lung Abscess
- Can Cause Pseudomembranous Colitis
Burns Assessment
- Stage and Extent of Burn
- Dyspnea
- Singed Nasal Hairs
- Pain
- Initial Decrease Urinary Output
- Paralytic Ileus
- Signs of Inadequate Hydration
- Shock
- Hypothermia
- Hyperkalemia
Stages of Burn Care
- Resuscitative/Emergent Phase
- Injury to Return of Capillary Permeability
- 48-72 hours
- IV Fluid Replacement
- Acute Phase
- Diuresis to Near Wound Closure
- Wound Closure to Return of Optimal Level
Burns Considerations
- Maintain Body Temperature
- Increased Risk of Infection
- Venous Thromboembolism (VTE) Prophylaxis
- Curling's Ulcer
- Excision and Grafting
- Adequate Nutrition
- Contractures
Burns Interventions
- Ensure Airway Patency
- O2
- IV Fluid Replacement
- Dry Sterile Dressing
- Debridement
- Elevate Burned Limbs
- Analgesics
- Silver Sulfadiazine
- Escharotomy
Atopic Dermatitis / Eczema
- Pruritic Vesicles
- Inflammatory Skin Rash
- Cheeks in Children
- Skin Flexural Areas
- Associated with Asthma and Allergic Rhinitis
- Tacrolimus
- Moisturizers
- Corticosteroids
- Phototherapy
- Avoid Triggers
- Antihistamines
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
- Topical Antimicrobial
- Burns
- Open Wound Care
- Mafenide
- Pain
- Acidosis
- Administer Analgesic Prior to Wound Care
Tacrolimus (Prograf) Overview
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Transplant Rejection
- Atopic Dermatitis
- Increased Lymphoma Risk
- Avoid Grapefruit Juice
Herpes Zoster (Shingles)
- Varicella-Zoster Virus
- Linear, Unilateral Rash Along a Dermatome
- Pruritus
- Postherpetic Neuralgia
- Acyclovir
- Analgesics
- Gabapentin
- Contagious Vesicles
- Shingrix
Gabapentin
- Seizure Treatment
- Peripheral Neuropathy
- Postherpetic Neuralgia
- Bipolar Disorder
- Migraine Prophylaxis
- Inhibits Voltage-Gated Ca2+ channels
- Designed as a GABA Analog
- Ataxia
- Sedation
Acyclovir (Zovirax)
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Headache
- GI Distress
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Prevents Recurrent Episodes
- Slow IV Infusion
Terbutaline (Brethine)
- Beta-2 Agonists
- Asthma
- Tocolytic
- Hypotension
- Tremor
- Tachycardia
- Pulmonary Edema
- Hyperglycemia
Griseofulvin
- Disrupts Microtubules in Mitosis
- Antifungal for Superficial Infections
- Tinea and Ringworm
- Teratogen
- P450 Inducer
- Confusion
- Headache
Epinephrine
- Alpha Agonist
- Beta Agonist
- Hypotension
- Anaphylaxis
- Allergy
- Glaucoma
Psoriasis
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
Cyclosporine (Sandimmune) Overview
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
TNF-Alpha Inhibitor Drugs and Complications
- Etanercept
- Decoy TNF- Alpha receptor
- Anti-TNF- Alpha antibody
- Adalimumab
- Infliximab
- Increased risk of infection
- Predispose to Tuberculosis (TB) reactivation
- Order Baseline PPD- skin test
- Quantiferon Gold In-Tube
- Order Chest X-Ray
TNF-Alpha Inhibitors Overview
- Downregulates Pro-inflammatory Cytokines
- Decreased Lymphocyte Activation and Migration
- Granuloma Breakdown
- Crohn's Disease
- Rheumatoid Arthritis
- Juvenile Rheumatoid Arthritis
- Psoriasis
- Ankylosing Spondylitis
Cancer Warning Signs (CAUTION)
- Change in Bowel or Bladder Habits
- A Sore That Does Not Heal
- Unusual Bleeding or Discharge
- Thickening or Lump in the Breast or Elsewhere
- Dyspepsia (Indigestion)
- Obvious Change to Warts or Moles
- Nagging Cough
ABCDEs of Melanoma
- Asymmetry
- Border
- Color
- Diameter
- Evolving
Actinic Keratosis
- Sun Exposure
- Papules or Plaques
- Small, Rough
- Erythematous
- Precursor to Squamous Cell Carcinoma
Pregabalin (Lyrica)
- GABA Analog
- Seizures
- Neuropathic Pain
- Fibromyalgia
- Headache
- Dizziness
- Somnolence (Fatigue)
- Weight Gain
- Angioedema
- Rhabdomyolysis
- Dependence
Basal Cell Carcinoma of the Skin
- Most Common Skin Cancer
- 2/3 of Cases Due to UV Light Exposure
- Pink, Pearl-like Lesions
- Rolled Borders
- Telangiectasias
- Commonly Upper Lip
- Shave Biopsy
- Pallisading Nuclei
- Mohs Micrographic Surgery
Squamous Cell Carcinoma of the Skin
- 2nd Most Common Skin Cancer
- UV Light Exposure
- Long-term Immunosuppression
- Arsenic Exposure
- Ulcerative Red Lesion
- Precursor Actinic Keratosis
- Commonly Lower Lip
- Biopsy shows Keratin Pearls
- Mohs Micrographic Surgery
Anaphylaxis Intervention
- Assess Airway and Oxygen Needs
- Reassure Patient with Anxiety
- Supine Position
- Methylprednisolone (Solu-medrol)
- Epinephrine
- Diphenhydramine (Benadryl)
- Medical Alert Bracelet
Staphylococcus aureus Disease
- Skin Infections
- Impetigo
- Abscesses
- Exfoliative Toxin
- Scalded Skin Syndrome
- Toxic Shock Syndrome (TSST 1)
- Binds to MHC II and T Cell Receptor
- Food Poisoning
- Acute Bacterial Endocarditis
- Pneumonia
- Osteomyelitis
Staphylococcus aureus Characteristics
- Gram-Positive
- Cocci
- Catalase-Positive
- Coagulase-Positive
- Beta-Hemolytic
- Protein A Virulence Factor
- Inhibits Phagocytosis
- MRSA
- Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
Lyme Disease
- Transmitted by Ticks (Vector-borne)
- Flu-like Symptoms
- Bulls Eye Rash (Erythema Migrans)
- Joint Pain and Stiffness
- Facial Paralysis
- Antibiotics
- Prevention
Borrelia burgdorferi
- Lyme Disease
- Spirochete
- Dark-field Microscopy
- Giemsa Stain
- Silver Stain
- White-footed Mouse
- Ixodes Tick
- Babesia
- Anaplasmosis
- Flu-like Symptoms
- Erythema Migrans
- Bulls Eye Rash
- Bilateral Bell's Palsy
- Conduction Defects
- Arthropathy
- Doxycycline
- Ceftriaxone
Nystatin
- Candidiasis
- Vaginal
- Oral
- Cutaneous
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
- Topical form of Amphotericin B
- Rash
Tacrolimus (Prograf) Side Effects
- Nephrotoxicity
- Neurotoxicity
- GI Distress
- Infection
- Hypertension
- Hyperkalemia
- Hyperglycemia
Metronidazole
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Metallic taste
- Disulfiram like Reaction with Alcohol