Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Inhibit H+/K+/ATPase
- Hip fracture
- Pneumonia
H2 Receptor Blocker
- "-tidine" Suffix
- Gastroesophageal Reflux Disease (GERD)
- Peptic Ulcer
- Block Histamine H2 Receptors
- Parietal Cells
H2 Receptor Blocker Side Effects
- Decrease Creatinine Clearance
- Cimetidine
- Crosses Blood-Brain Barrier
- Anti-Androgen
- Inhibits Cytochrome P450
Cimetidine and Famotidine (H2 Receptor Blockers)
- -tidine Suffix
- H2 Receptor Blocker
- Suppress Gastric Acid Secretion
- Pneumonia
- Anti-androgen Effects
- CNS Changes
Pancreatin, Pancrelipase (Pancreatic Enzymes)
- Pancreatic Enzymes
- Cystic Fibrosis
- Pancreatic Insufficiency
- GI Distress
- Inactivated by Gastric Acid
- 24 Hour Fat Excretion
- Take with Every Meal and Snack
Sucralfate (Carafate)
- Creates Protective Barrier
- GI Ulcers
- Constipation
- Require Acidic Environment
- Give on Empty Stomach
- Oral Suspension Available
- May Decrease Absorption of Other Meds
Activated Charcoal (Actidose)
- Binds to Toxins
- Ingested Poison
- Black Stool
- GI Distress
- Give As Soon As Possible
- Via Mouth or NG Tube
- Gastric Lavage
- Do Not Administer with Antidotes
Promethazine (Phenergan)
- Histamine H1 Receptor Antagonist
- Weak Dopamine Antagonist
- Nausea and Vomiting
- Motion Sickness
- Respiratory Depression
- Sedation
- Anticholinergic Effects
- Extrapyramidal Symptoms
- Use Large Bore IV
- Monitor for Tissue Necrosis
Octreotide
- Acute Variceal Bleeds
- Pituitary Tumors
- GH Secreting Tumors
- Carcinoid Tumors
- VIPoma
- Somatostatin Analog
Ondansetron
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Headache
- Constipation
- QT Prolongation
Metoclopramide
- Antiemetic
- Promotility Agent
- Increased Resting Tone
- Antagonist at D2 Receptor
- Parkinsonian Symptoms
- Galactorrhea
- Small Bowel Obstruction
- Parkinson's Disease
Aluminum Hydroxide
- Antacid
- Constipation
- Hypophosphatemia
- Osteodystrophy
- Proximal Muscle Weakness
- Seizures
- Chelating Agent
Calcium Carbonate
- Antacid
- Dietary Supplement
- Hypercalcemia
- Milk-Alkali Syndrome
- Rebound Hyperacidity
- Chelating Agent
Magnesium Hydroxide
- Antacid
- Osmotic Laxative
- Diarrhea
- Hypermagnesemia
- Hyporeflexia
- Hypotension
- Cardiac Arrest
- Chelating Agent
Osmotic Laxatives
- Increases Osmotic Load
- Hepatic Encephalopathy
- Constipation
- Magnesium Hydroxide
- Magnesium Citrate
- Polyethylene Glycol
- Sorbitol
- Lactulose
- Diarrhea
- Dehydration
- Misused in Bulimia Nervosa
Orlistat
- Inhibits Gastric and Pancreatic Lipase
- Decrease Absorption of Fat
- Weight Loss
- Increased Bowel Movements
- Steatorrhea
- Abdominal Pain
- Flatulence
- Calcium Oxalate Kidney Stones
- Decreased Absorption of Fat-Soluble Vitamins
Hepatitis C Pharmacotherapy
- Glecaprevir
- Grazoprevir
- Simeprevir
- Ledipasvir
- Elbasvir
- Velpatasvir
- Sofosbuvir
- Ribavirin