Heparin (Unfractionated)
- Suppresses Coagulation
- Deep Vein Thrombosis (DVT)
- Pulmonary Embolism
- Hemorrhage
- Heparin-Induced Thrombocytopenia (HIT)
- Monitor aPTT
- Preferred (Safe) During Pregnancy
- Protamine Sulfate
PT/PTT Lab Values
- Prothrombin Time (PT)
- 10-14 seconds
- Activated Partial Thromboplastin Time (PTT or aPTT)
- 25-35 seconds
Enoxaparin (Lovenox)
- Inhibits Clotting Factors
- Factor Xa
- Clot Formation Prevention
- Heparin Induced Thrombocytopenia (HIT)
- Bleeding
- Medication Education
- Subcutaneous Injection
- 2 Inches from Umbilicus or Incisions
- Protamine Sulfate
Warfarin (Coumadin)
- Inhibits Clotting Factors
- Atrial Fibrillation
- Venous Thrombosis
- Pulmonary Embolism
- PT/INR Levels
- Observe for Bleeding
- Pregnancy
- Vitamin K and Fresh Frozen Plasma
- Prolonged Therapeutic Onset
- Maintain Same Diet
Warfarin Antidotes
- Vitamin K
- Fresh Frozen Plasma
INR Lab Value
- 0.8-1.2 Normal Range
- Warfarin
- 2.0-3.0
Digoxin (Lanoxin)
- Increases Inotropy
- Heart Failure
- Atrial Fibrillation
- Bradycardia
- Fatigue
- Heart Block
- Heart Rate Below 60
- Hypokalemia
- Monitor for Toxicity and Visual Changes
- Digibind
Alteplase
- Tissue Plasminogen Activator
- Thrombosis
- Bleeding
- Intracranial Hemorrhage
- Internal Hemorrhaging
- Minimize Bleeding
- Monitor for Shock
- Aminocaproic Acid
Clopidogrel (Plavix)
- ADP Receptor Antagonist
- Prevent Platelet Aggregation
- Acute Coronary Syndrome (ACS)
- Prevention of Thrombotic Events
- Bleeding
- Thrombotic Thrombocytopenic Purpura (TTP)
- Pancytopenia
- Abdominal Pain
- Withhold Before Surgery
Abciximab and Tirofiban (GP IIb/IIIa Inhibitors)
- IIb/IIIa Receptor Inhibitors
- Inhibits Platelet Aggregation
- Thrombotic Event Prevention
- Acute Coronary Syndrome (ACS)
- Percutaneous Coronary Intervention (PCI)
- Bleeding
- Expensive
- Combination Drug Therapy
Acute Digoxin Toxicity
- Hyperkalemia
- Cholinergic (Nausea, Vomiting, Diarrhea)
- Blurry Yellow Green Vision with Halo of Light
- Arrhythmia
- Bradycardia
- Prolonged PR interval
- Decreased QT
- Scooping on EKG
- T Wave Inversion
Digoxin Toxicity Treatment
- Activated Charcoal
- Slowly Normalize K+
- Digibind (Anti-Digoxin Fab)
- Magnesium Sulfate
- Lidocaine
- Cardiac Pacing
Beta Blockers
- "-olol" suffix
- Decreases Heart Rate and Contractility
- Decreases Peripheral Vascular Resistance
- Decreases Renin Release
- Hypertension
- Heart Failure
- Angina Pectoris
- Asthma and Heart Block Patients
- Assess Blood Pressure and Heart Rate
- Masking Signs of Hypoglycemia
- Do Not Stop Abruptly
Calcium Channel Blockers (Verapamil and Diltiazem)
- Slows AV Conduction
- Angina Pectoris
- Arrhythmias
- Essential Hypertension
- Bradycardia
- Hypotension
- Constipation
- Peripheral Edema
- Gingival Hyperplasia
- Medication Education
Prazosin (Minipress)
- -osin suffix
- Selective Alpha-1 Receptor Blocker
- Hypertension
- Benign Prostatic Hyperplasia (BPH)
- Nightmares
- Orthostatic Hypotension
- Tachycardia
- Priapism / Inhibition of Ejaculation
- Nasal Congestion
- First Dose Effect
- Administer at Bedtime
Hydralazine (Apresoline)
- Severe Hypertension
- CHF
- Reduced Afterload
- Pregnancy
- Vasodilates Arterioles
- Drug-induced Lupus
- Reflex Tachycardia
- Hypotension
- Combined with Diuretic and Beta Blocker
Nitroglycerin
- Decreases Preload
- Angina
- Up to 3 doses q 5 mins
- Headache
- Hypotension
- Viagra (Sildenafil)
- Assess Blood Pressure
- Protect From Light
- Use Glass Bottle and Special Tubing
- Gloves for Applying Topically
Sodium Nitroprusside (Nitropress)
- Venous and Arterial Dilation
- Hypertensive Crisis
- Cyanide Toxicity
- Thiocyanate Toxicity
- Hypotension
- Short Term Administration
- Light Sensitive, Use Container
- Continuous BP Monitoring
Phenytoin (Dilantin)
- Blocks Na+ Channels
- Tonic-clonic Seizures
- Ataxia
- Nystagmus
- Sedation
- Gingival Hyperplasia
- Purple Glove Syndrome
- Hirsutism
- Rash
- Anemia
- Individualized Dosing
Adenosine (Adenocard)
- Slows AV Conduction
- Supraventricular Tachycardia (Paroxysmal)
- Bradycardia
- Flushing
- Dyspnea
- Rapid IV Push
- Caffeine and Theophylline Decrease Effectiveness
- Dipyridamole May Intensify Effects
Dobutamine
- Beta-1 Agonist
- Inotropic
- Heart Failure
- Tachycardia
- Arrhythmias
- Closely Monitor Patients
- Other Meds May Increase Potency
Epinephrine (Adrenaline)
- Alpha and Beta Agonist
- Anaphylaxis
- Primary Open Angle Glaucoma (POAG)
- Bleeding
- Cardiac Arrest
- Tachycardia
- Hypertension
- Tremors
- Insomnia
- Multiple Strengths
Atorvastatin (Lipitor)
- -statin Suffix
- HMG-CoA Reductase Inhibitors
- High Cholesterol
- Hepatotoxicity
- Rash
- Rhabdomyolysis
- Myopathy
- Monitor Liver Enzymes
- Administer at Bedtime
- Avoid Grapefruit
Ezetimibe
- Hyperlipidemia
- Cholesterol Absorption Blocker
- Decreases LDL
- Diarrhea
- Increased LFT Values
Vitamin B3 - Niacin (Nicotinic Acid)
- Decreases Triglycerides
- Decreases LDL
- Increases HDL
- Dyslipidemia
- Pellagra
- Diarrhea
- Dermatitis
- Dementia
- Flushing
- GI Distress
- Hepatotoxicity