Alteplase
- Tissue Plasminogen Activator
- Thrombosis
- Bleeding
- Intracranial Hemorrhage
- Internal Hemorrhaging
- Minimize Bleeding
- Monitor for Shock
- Aminocaproic Acid
Warfarin Antidotes
- Vitamin K
- Fresh Frozen Plasma
Warfarin (Coumadin)
- Inhibits Clotting Factors
- Atrial Fibrillation
- Venous Thrombosis
- Pulmonary Embolism
- PT/INR Levels
- Observe for Bleeding
- Pregnancy
- Vitamin K and Fresh Frozen Plasma
- Prolonged Therapeutic Onset
- Maintain Same Diet
Heparin (Unfractionated)
- Suppresses Coagulation
- Deep Vein Thrombosis (DVT)
- Pulmonary Embolism
- Hemorrhage
- Heparin-Induced Thrombocytopenia (HIT)
- Monitor aPTT
- Preferred (Safe) During Pregnancy
- Protamine Sulfate
Heparin Induced Thrombocytopenia (HIT)
- 5-10 Days After Heparin Exposure
- Heparin-Platelet Factor 4 Complex
- Autoantibodies Form Against Complex
- Heparin-Platelet Factor 4-Antibody Complex Binds Platelets
- Platelet Aggregation
- Procoagulant Release
- Thrombocytopenia
- Serotonin Release Assay (SRA)
- Stop Heparin, Start Direct Thrombin Inhibitor
Enoxaparin (Lovenox)
- Inhibits Clotting Factors
- Factor Xa
- Clot Formation Prevention
- Heparin Induced Thrombocytopenia (HIT)
- Bleeding
- Medication Education
- Subcutaneous Injection
- 2 Inches from Umbilicus or Incisions
- Protamine Sulfate
Atropine
- Muscarinic Antagonist
- Bradycardia
- Increased Exocrine Secretions
- Smooth Muscle Spasms
- Tachycardia
- Dry Mouth
- Urinary Retention
Nitroglycerin
- Decreases Preload
- Angina
- Up to 3 doses q 5 mins
- Headache
- Hypotension
- Viagra (Sildenafil)
- Assess Blood Pressure
- Protect From Light
- Use Glass Bottle and Special Tubing
- Gloves for Applying Topically
Adenosine (Adenocard)
- Slows AV Conduction
- Supraventricular Tachycardia (Paroxysmal)
- Bradycardia
- Flushing
- Dyspnea
- Rapid IV Push
- Caffeine and Theophylline Decrease Effectiveness
- Dipyridamole May Intensify Effects
Lidocaine
- Blocks Na+ Channels
- Ventricular Arrhythmia
- Anesthetic
- Paresthesias
- Seizures
- Respiratory Depression
- Drowsiness
- Anesthetic Effects Extended with Epinephrine
Dobutamine
- Beta-1 Agonist
- Inotropic
- Heart Failure
- Tachycardia
- Arrhythmias
- Closely Monitor Patients
- Other Meds May Increase Potency
Epinephrine (Adrenaline)
- Alpha and Beta Agonist
- Anaphylaxis
- Primary Open Angle Glaucoma (POAG)
- Bleeding
- Cardiac Arrest
- Tachycardia
- Hypertension
- Tremors
- Insomnia
- Multiple Strengths
Norepinephrine (Levophed)
- Alpha Agonist
- Beta-1 Agonist
- Severe Hypotension
- Decreases Renal Blood Flow
- Arrhythmias
- Hypertension
- Tissue Necrosis
- Last Resort Medication
Nitroprusside
- Direct Release of NO
- Increase cGMP
- Short Half-Life
- Malignant Hypertension
- Cyanide Toxicity
Loop Diuretics
- Thick Ascending Limb of Loop of Henle
- Inhibits Na+-K+-2Cl-
- Sulfa Drug
- Furosemide
- Lasix
- Ototoxicity from Rapid Injection
- Gout
- Dehydration
- Hypocalcemia
- Hypokalemia
- Orthostatic Hypotension
Loop Diuretic Education
- Furosemide (Lasix)
- Heart Failure
- Pulmonary Edema
- Acute Renal Failure (ARF)
- Edema
- Notify the provider of weakness, dizziness, or muscle cramping
- Increase Potassium Intake
- Check BP Daily
- Daily Weights and Monitor IandOs
Mannitol (Osmitrol)
- Osmotic Diuresis
- Reducing Intracranial Pressure
- Reducing Intraocular Pressure
- Renal Failure Prophylaxis
- Edema
- Fluid and Electrolyte Imbalance
- Avoid Use in Cardiac Patients
- IV Administration
Naloxone (Narcan)
- Competitive Opioid Receptor Antagonist
- Opioid Induced CNS Depression
- Severe Nausea and Vomiting
- Excitable State
- Opioid Withdrawal Symptoms
- Repeated Dosing Often Required
Oxycodone
- Opioid Receptor Agonist
- Refractory Pain
- Respiratory Depression
- Constipation
- CNS Depression
- Addiction
- Naloxone
Fentanyl
- Opioid Receptor Agonist
- High Potency
- Anesthesia Induction
- Chronic Pain
- Breakthrough Pain
- CNS Depression
- Respiratory Depression
- Constipation
- Miosis
- Addiction
Buprenorphine-Naloxone (Suboxone)
- Combination Drug
- Partial Opioid Receptor Agonist (Buprenorphine)
- Opioid Receptor Antagonist (Naloxone)
- Opioid Use Disorder
- CNS Depression
- Diaphoresis
- Hypotension
- Low Abuse Potential