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Pharmacology | Pharmacist (Pharm.D) School Study Aid
Acetazolamide
- Indications
- Glaucoma
- Altitude Sickness
- Pseudotumor Cerebri
- CHF
- Metabolic Alkalosis
- Mechanism of Action
- Carbonic Anhydrase Inhibitor
- Sodium Bicarbonate (NaHCO3) Diuresis
- Side Effects
- Metabolic Acidosis
- Paresthesias
1 min
Mannitol (Osmitrol)
- Indications
- Increased Intracranial Pressure (ICP)
- Glaucoma
- Drug Overdose
- Mechanism of Action
- Osmotic diuretic
- Increased Urine Flow
- Side Effects
- Dehydration
- Contraindications
- Anuria
- CHF
2 mins
Loop Diuretics
- Mechanism of Action
- Thick Ascending Limb of Loop of Henle
- Inhibits Na+-K+-2Cl- Symporter
- Sulfa Drug
- Drug Names
- Furosemide
- Lasix
- Side Effects
- Gout
- Ototoxicity
- Hypocalcemia
- Hypokalemia
4 mins
Mannitol (Osmitrol)
- Mechanism
- Osmotic Diuresis
- Indications
- Reducing Intracranial Pressure
- Reducing Intraocular Pressure
- Renal Failure Prophylaxis
- Side Effects
- Edema
- Fluid and Electrolyte Imbalance
- Considerations
- Avoid Use in Cardiac Patients
- IV Administration
2 mins
Ethacrynic Acid
- Mechanism of Action
- Non-sulfa Drug
- Phenoxyacetic Acid Derivative
- Loop Diuretic
- Inhibits Na+-K+-2Cl- Cotransporter
- Thick Ascending Loop of Henle
- Clinical Use
- Diuresis
- Side Effects
- Hypokalemia
- Ototoxicity
- Gout
2 mins
Thiazide Diuretics
- Early Distal Tubule
- Inhibits Na/Cl Reabsorption
- Sulfa Drug
- Hyperglycemia
- Hyperlipidemia
- Hypercalcemia
- Hyperuricemia
- Hyponatremia
- Hypokalemic Metabolic Alkalosis
2 mins
Hydrochlorothiazide HCTZ
- Mechanism of Action
- Inhibits Reabsorption NaCl and H2O
- Indications
- Edema
- Mild to Moderate Hypertension
- Side Effects
- Hypokalemia
- Hyponatremia
- Dehydration
- Hyperglycemia
- Gout
- Contraindications
- Sulfa Allergy
- Pregnancy and Breastfeeding
1 min
K+ Sparing Diuretics
- Indications
- CHF and Hypertension
- Hypokalemia
- Hyperaldosteronism
- Mechanism of Action
- Collecting Tubule
- Spironolactone
- Competitive Aldosterone Receptor Antagonist
- Amiloride and Triamterene
- Block Na+ Channels
- Side Effects
- Hyperkalemia
- Gynecomastia
2 mins
Spironolactone (Aldactone)
- Mechanisms
- Inhibition of Aldosterone
- Potassium Retention
- Indications
- Hypertension
- Edema
- Heart Failure
- Side Effects
- Hyperkalemia
- Endocrine Effects
- Consideration
- Avoid Potassium Supplements
2 mins
ACE Inhibitors
- -Pril Suffix
- Indications
- Hypertension
- CHF
- Diabetic Nephropathy
- Mechanism of Action
- Inhibits ACE
- Decreases GFR
- Inhibits Constriction of Efferent Arteriole
- Side Effect
- Increased Bradykinin
- Cough
1 min
ACE Inhibitor Toxicity
- CAPTOPRIL Mnemonic
- Cough
- Angioedema
- Potassium Changes (Hyperkalemia)
- Taste Change
- Hypotension
- Pregnancy Changes
- Rash
- Increased Renin
- Lower Angiotensin II
2 mins
Angiotensin Receptor Blockers (ARBs)
- -sartan suffix
- Indications
- Hypertension
- CHF
- Diabetic Nephropathy
- Mechanism of Action
- Angiotensin II Receptor Blockers
- Side Effect
- Hyperkalemia
- Contraindication
- Pregnancy
1 min
Angiotensin II Receptor Blockers (ARBs)
- Ends in "-sartan"
- Mechanism of Action
- Blocks Angiotensin II Receptor
- Indications
- Hypertension
- Side Effects
- Angioedema
- Contraindications
- Renal Artery Stenosis
- Pregnancy
1 min
Erythropoietin
- Mechanism
- Stimulates RBC Production
- Indications
- Chronic Renal Failure
- Anemia
- Side Effects
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Considerations
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
2 mins
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