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Pharmacology | Pharmacist (Pharm.D) School Study Aid
Barbiturates
- Barb- Drug Names
- Indications
- Seizure Treatment
- Anesthesia Induction
- Mechanism of Action
- Increased Duration of Cl- Channel Opening
- Decrease Neuron Firing
- Side Effects
- Sedation
- Cardiovascular and Respiratory Depression
- CNS Depression
- P450 inducer
2 mins
Phenobarbital (Barbiturates)
- Mechanism
- Barbiturate
- Indications
- Seizures
- Side Effects
- Ataxia
- Paradoxical Excitement
- Fatigue/Drowsiness
- Considerations
- Monitor Plasma Levels
- High Potential for Abuse
1 min
Benzodiazepines Overview
- Indications
- First Line for Status Epilepticus
- Anesthesia Induction
- Anxiety
- Eclampsia
- Detoxification
- Mechanism of Action
- '-zepam' and '-zolam" Suffix
- Increase Frequency of Cl- Channel Opening
- Side Effects
- Decrease REM Sleep
- CNS Depression
- Dependence
- Antidote
- Flumazenil for Overdose
2 mins
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Zolpidem (Ambien)
- Mechanism
- Hypnotic
- Indications
- Insomnia
- Side Effects
- Daytime Drowsiness
- Bizarre Sleep Behaviors
- Sleep Driving
- Angioedema
- Considerations
- Short Term Administration
- Take Immediately Before Bedtime
1 min
Triazolam (Halcion)
- Mechanism
- Rapid-Onset Benzodiazepine
- Indications
- Insomnia
- Side Effects
- Rebound Insomnia
- Respiratory Depression
- Hypotension
- Paradoxical Excitement
- Amnesia
- Confusion
- Contraindications
- Pregnancy
- Considerations
- Short-Term Administration
2 mins
Nonbenzodiazepine Hypnotics
- Indications
- Insomnia
- Mechanism of Action
- Short Half-Life
- Acts on BZ1 GABA receptor
- Less dependence
- Drugs
- Zolpidem (Ambien)
- Side Effects
- Ataxia, confusion
- Antidote
- Flumazenil for Overdose
1 min
Buspirone
- Indications
- Generalized Anxiety
- Mechanism of Action
- Releases Dopamine and NE
- Stimulates 5-HT1A receptors
- Side Effects
- Low Side Effect Profile
- Safer with Alcohol than Other Anxiolytics
1 min
Trazodone
- Indications
- Insomnia
- Depression
- Mechanism of Action
- Inhibit Serotonin Reuptake
- Alpha-1 Blocker
- Histamine (H1) Blocker
- Side Effects
- Sedation
- Orthostatic Hypotension
- Dry Mouth
- Priapism
- Arrhythmias
2 mins
Short-acting Benzodiazepines
- Mnemonic
- ATOM
- Drug Names
- Alprazolam
- Triazolam
- Oxazepam
- Midazolam
- Indications
- Anesthesia Induction
- Insomnia
- Anxiety
- Considerations
- Half-life < 12 Hours
- Dependence
2 mins
Long-acting Benzodiazepines
- Drug Names
- Lorazepam
- Diazepam
- Clonazepam
- Chlordiazepoxide
- Indications
- Insomnia
- Anxiety
- Seizures
- Eclampsia
- Alcohol Withdrawal
- Considerations
- Half-life > 24 Hours
- Dependence
3 mins
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