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PANCE Prep Pearls: 3rd Ed. (2019)
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Infectious Disorders

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PANCE Prep Pearls: 3rd Ed. (2019) | Physician Assistant (PA) School Study Aid

Infectious Disorders
29 Picmonics to Learn | 52 mins
Influenza
Assessment
High Fever
Cough
Headache
Muscle Aches
Chills
Intervention
Vaccination
Drug Therapy
Zanamivir (Relenza)
Oseltamivir (Tamiflu)
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2 mins
Bordetella pertussis
Pathophysiology
Gram-Negative
Coccobacillus
Bordet-Gengou Agar
ADP Ribosylating AB Toxin
Inhibits Gi to cause Increase in cAMP
Signs AND Symptoms
Lymphocytosis
Increase in Insulin
Catarrhal Phase is Infectious Period
Paroxysmal Phase is Symptomatic Period
Whooping Cough
Treatment
Macrolides
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4 mins
Epiglottitis Assessment
Cause/Mechanism
Haemophilus Influenzae
Assessment
Drooling
Fever
Stridor
Restlessness
Dyspnea
Cough
Tripod Position
Considerations
Emergency Treatment
Do Not Examine Throat
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2 mins
Epiglottitis Interventions
Interventions
Maintain Airway
Upright/Sitting Position
Humidified Oxygen
Intubation/Tracheostomy Supplies At Bedside
IV Antibiotics
Decrease Anxiety
Considerations
NPO
Vaccine
Restrain to Prevent Extubation
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2 mins
Croup (Laryngotracheobronchitis)
Mechanism
Parainfluenza Virus
Assessment
3 Months to 3 Years
Nighttime
Barking Seal Cough
Inspiratory Stridor
Interventions
Cool Humidified Air
Dexamethasone
Racemic Epinephrine
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2 mins
Pneumonia Assessment
Risk Factors
Older Adult
Immunocompromised
Long Term Care
Assessment
Shortness of Breath (SOB)
Hypoxemia
Cough and Sputum Production
Wheezing or Crackles
Fever
Pleuritic Pain
Diagnosis
Chest X-ray
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2 mins
Common Causes of Pneumonia: Neonates (< 4 Weeks Old)
Group B Streptococci
E. coli
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44 secs
Common Causes of Pneumonia: Children (4 Weeks - 18 Years)
Runts May Cough Chunky Sputum
RSV (Viruses)
Mycoplasma
Chlamydia pneumoniae
Chlamydia trachomatis
Streptococcus pneumoniae
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1 min
Common Causes of Pneumonia: Adults (18 - 40 Years Old)
Mycoplasma
Streptococcus pneumoniae
Chlamydia pneumoniae
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41 secs
Common Causes of Pneumonia: Middle-Aged Adults (40 - 65 Years Old)
Streptococcus pneumoniae
Mycoplasma
Haemophilus influenzae
Anaerobes
Viruses
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1 min
Common Causes of Pneumonia: Elderly (65+ Years Old)
Influenza Virus
Haemophilus influenzae
Anaerobes
Streptococcus pneumoniae
Gram-Negative Rods
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59 secs
Pneumonia Intervention
Interventions
Humidified Oxygen
Deep Breathing Exercises
Position of Comfort
Increase Fluid Intake
Manage Fever
Medications
Antibiotics
Mucolytics
Expectorants
Considerations
Pneumococcal Vaccine
Sepsis
Acute Respiratory Failure (ARF)
Prevention Education
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2 mins
Streptococcus Pneumoniae Characteristics
Characteristics
Gram-Positive
Diplococci
Lancet-Shaped
Catalase-Negative
Optochin-Sensitive
Bile Soluble
Alpha-Hemolytic
Polysaccharide Capsule
Positive Quellung Reaction
IgA Protease
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1 min
Haemophilus Influenzae Disease
Disease
Pneumonia
Cherry Red Epiglottitis
Meningitis
Otitis Media
COPD Exacerbation
Thumbprint Sign (on X-ray)
Treatment
Rifampin Prophylaxis
Ceftriaxone
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2 mins
Haemophilus influenzae Characteristics
Characteristics
Gram-Negative
Coccobacilli
PRP Capsule in Type B
Positive Quellung Reaction
IgA Protease
Chocolate Agar
Factor V is NAD
Factor X is Hematin
Staph Aureus Provides Factor V
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2 mins
Staphylococcus aureus Characteristics
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Positive
Beta-Hemolytic
Protein A Virulence Factor
Inhibits Phagocytosis
MRSA
Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
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2 mins
Klebsiella Disease
Signs and Symptoms
Aspiration Pneumonia
Alcoholics
Diabetics
Red Currant Jelly Sputum
Lung Abscess
Nosocomial Urinary Tract Infection
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2 mins
Klebsiella Characteristics
Characteristics
Gram-Negative
Bacilli
Oxidase-Negative
Intestinal Flora
Antiphagocytic Virulence Factor
Polysaccharide Capsule
Positive Quellung Reaction
Mucoid Colonies
Urease-Positive
Fast Lactose Fermenter
Pink on MacConkey Agar
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2 mins
Atypical Pneumonia
CHARACTERISTICS
Diffuse Patchy Inflammation
Interstitial Pattern
"Walking Pneumonia"
Etiologies
Mycoplasma pneumoniae
Chlamydia pneumoniae
Legionella pneumophila
Adenovirus
Respiratory Syncytial Virus (RSV)
Cytomegalovirus (CMV)
Influenza
Presentation
Dry Cough
Treatment
Macrolides
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2 mins
Mycoplasma Pneumoniae
Characteristics
No Cell Wall and No Gram Stain
Cholesterol Membrane
Eaton's Agar
Mulberry Colonies
Disease
Atypical pneumonia
Military Recruits
Cold IgM Autoimmune Hemolytic Anemia
Erythema Multiforme
Treatment
Tetracycline
Erythromycin
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2 mins
Legionella Disease
Signs and Symptoms
High Fever
Diarrhea
Increased Liver Enzymes
Hyponatremia
Type IV Renal Tubular Acidosis
Severe Atypical Pneumonia
Pontiac Fever
Treatment
Fluoroquinolones
Macrolides
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2 mins
Legionella Characteristics
Characteristics
Bacillus
Poor Gram Stain
Charcoal Yeast with Iron and Cysteine
Silver Stain
Water Sources
Smokers and Heavy Drinkers
Detect Antigen in Urine
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2 mins
Histoplasmosis
Fungi
2-5 um
Yeast Cells within Macrophages
Starling Bird Poop
Bat Poop
Caves
Mississippi and Ohio River Valleys
Pneumonia
Caseating Granuloma
Erythema Nodosum
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1 min
Pneumocystis jirovecii
Fungi
AIDS/Immunocompromised
Fever
Hypoxemia
Bronchoalveolar Lavage
Biopsy
Methenamine Silver Stain
Saucer/cup shaped yeast forms
Diffuse interstitial pneumonia CXR
TMP-SMX
Start prophylaxis when CD4 drops under 200
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1 min
Mycobacterium Tuberculosis Disease
CONSTITUTIONAL SYMPTOMS/PULMONARY TUBERCULOSIS
Fever
Night Sweats
Weight Loss
Hemoptysis
EXTRA-PULMONARY TUBERCULOSIS
Extrapulmonary Disease
Addison's Disease
CNS
Liver
Kidneys
GI
Bones
Pott's Disease
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3 mins
Mycobacterium Tuberculosis Characteristics
Characteristics
Mycolic Acid Cell Wall
Acid-fast
Carbolfuchsin Stain Red
Lowenstein-Jensen Agar
Serpentine Cord Factor
Primary TB
Primary TB
Caseating Granuloma
Ghon Focus
Hilar Lymph Nodes
Ghon Complex
Reactivation TB
Reactivation TB
Reactivation in Apex
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3 mins
Tuberculosis Assessment
Etiology
Airborne Droplet
Assessment
3 Week Productive Cough
Night Sweats
Chest Pain
Fever
Weight Loss
Fatigue
Diagnosis
Chest X-Ray
Blood Tests
Mantoux Skin Test
3 Positive Sputum Tests
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1 min
Tuberculosis Skin Mantoux Test (PPD)
Delayed Hypersensitivity (Cell Mediated Response)
Intradermal Injection
Read 48-72 hours
Positive Results
≥ 5 mm Induration
Immunosuppressed
≥ 10 mm Induration
High Risk Patients
≥ 15 mm Induration
Considerations
Chest X-Ray
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3 mins
Tuberculosis Intervention
Hospital Care
Airborne Isolation
Drug Therapy
Combination Drug Therapy (RIPE)
6-12 Months
Considerations
DOT
BCG Vaccination
Medication Education
3 Negative Sputum Specimens
Infection Control
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2 mins

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