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PANCE Prep Pearls: 3rd Ed. (2019) | Physician Assistant (PA) School Study Aid
Diverticulosis and Diverticulitis Assessment
- Diverticulosis
- Outpouching
- Diverticulitis
- Inflamed Diverticula
- Assessment
- Abdominal Pain
- Abdominal Distention
- Flatulence
- Fever
- Rectal Bleeding
- Alternating Constipation and Diarrhea
- Considerations
- Peritonitis
2 mins
Diverticulosis and Diverticulitis Interventions
- Interventions
- High Fiber Diet
- Reduce Intra-abdominal Pressure
- Stool Softeners
- Exercise
- Anticholinergics
- Considerations
- Antibiotics
- Bowel Resection
2 mins
Crohn's Disease Characteristics
- Terminal Ileum and Colon
- Rectal Sparing
- Transmural Inflammation
- Granulomas
- Skip Lesions
- Cobblestone Mucosa
- Fissures
- Fistulas
- Perianal Disease
- Creeping Fat
- Lymphoid Aggregates
- String Sign on Barium Swallow
2 mins
Crohn's Symptoms and Associations
- Diarrhea
- Malabsorption
- Bile-Wasting
- Pigment Gallstones
- Oxalate Kidney Stones
- Ankylosing Spondylitis
- Erythema Nodosum
- Uveitis
- Migratory Polyarthritis
2 mins
Crohn's Disease Assessment
- Diarrhea
- 5-6 per day
- Cramping Abdominal Pain
- Fever
- Weight Loss
- Malabsorption
- Anemia
- Complications
- Obstruction
- Fistulas
2 mins
Ulcerative Colitis Characteristics
- Autoimmune
- Mucosal and Submucosal Only
- Rectal Involvement
- Stepwise Lesions
- Friable Pseudopolyp
- Crypt Abscess
- Loss of Haustra
- Lead Pipe Appearance
- Bloody Diarrhea
2 mins
Ulcerative Colitis Associations
- Associations
- Toxic Megacolon
- Colorectal Carcinoma
- Anterior Uveitis
- Pyoderma Gangrenosum
- Ankylosing Spondylitis
- Primary Sclerosing Cholangitis
- P-ANCA
1 min
Ulcerative Colitis Assessment
- Assessment
- Cramping Abdominal Pain
- Tenesmus
- Bloody Diarrhea
- Up to 10-20 / Day
- Fever
- Complications
- Hemorrhage
1 min
Mesenteric Ischemia
- Signs and Symptoms
- Severe Abdominal Pain
- Bloody Diarrhea
- Metabolic Acidosis
- Diagnosis
- Increased WBC
- Increased Lactate (Lactic Acid)
- X-ray
- Air Within Bowel Wall
- CT Angiography
- Bowel Wall Edema
- Treatment
- Antibiotics
- Emergent Surgical Intervention
2 mins
Colorectal Cancer Assessment
- 3rd Most Common Cancer
- Assessment
- Change in Bowel Habits
- Bowel Obstruction
- Rectal Bleeding
- Anemia
- Weight Loss
- Ascites
- Considerations
- Colonoscopy
- FOBT and FIT
2 mins
Colorectal Cancer Interventions
- Interventions
- Surgical Colon Resection
- Radiation
- Chemotherapy
- Considerations
- Bowel Cleansing
- Screening
- Colostomy
- Dietary Consult
- Body Image
3 mins
Familial Adenomatous Polyposis
- Pathophysiology
- Autosomal Dominant
- Mutation in Chromosome 5
- APC Gene Mutation
- Overexpression of Beta-catenin
- Two-Hit Hypothesis
- Clinical Findings
- Change in Bowel Habits
- Colonic Polyps
- Screening
- Colonoscopy
- Management
- Prophylactic Surgery
- Considerations
- Progresses to Colorectal Carcinoma
3 mins
Turcot Syndrome
- Pathophysiology
- Autosomal Dominant or Autosomal Recessive
- Colonic Polyposis and a Malignant Central Nervous System Tumor
- Associations
- Increased Risk of Colorectal Cancer
- Increased Risk of Brain Cancer
- Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
- Glioblastoma Multiforme
- Familial Adenomatous Polyposis (FAP)
- Medulloblastoma
3 mins
Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
- Characteristics
- Autosomal Dominant
- Defective DNA Mismatch Repair
- 80% Risk of Colon Cancer Development
- Proximal (Right) Colon
- Type II associated with Endometrial, Ovarian and Skin Cancers
- 3-2-1 Rule
- 3 Relatives with Colon Cancer
- Occurs Across 2 Generations
- 1 Relative Diagnosed < 50 Years Old
- Treatment
- Frequent Screening
- Colectomy
3 mins
Peutz-Jeghers Syndrome
- Mechanism and Characteristics
- Symptomatic Age: 10-30 Years
- LKB1/STK11 Gene Mutation
- Autosomal Dominant
- Signs and Symptoms
- Benign GI Hamartomatous Polyps
- Mucocutaneous Hyperpigmentation
- Positive Family History
- Increased Risk of Colorectal Carcinoma
1 min
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