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PANCE Prep Pearls: 3rd Ed. (2019)
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Bacterial Diseases

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PANCE Prep Pearls: 3rd Ed. (2019) | Physician Assistant (PA) School Study Aid

Bacterial Diseases
16 Picmonics to Learn | 33 mins
Clostridium tetani
Characteristics
Gram-Positive
Bacilli
Obligate Anaerobic
Exotoxin
Spore-Forming
Renshaw Cells in the Spinal Cord
Blocks Glycine and GABA Release
Signs and Symptoms
Spasms
Risus Sardonicus
Lockjaw
Opisthotonus
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3 mins
Clostridium perfringens
Characteristics
Gram-Positive
Bacillus
Anaerobe
Spore-Forming
Alpha Toxin Lecithinase
Phospholipase
Heat Labile Enterotoxin
Signs and Symptoms
Myonecrosis
Gas Gangrene
Food Poisoning and Diarrhea
Treatment
Hyperbaric O2 Chamber
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2 mins
Clostridium botulinum
Characteristics
Bacillus
Gram-positive
Anaerobe
Spore-forming
Heat Labile Toxin
Inhibits Acetylcholine (Ach) Release at Neuromuscular Junction (NMJ)
Canned Food in Adults
Spores in Honey
Signs and Symptoms
Descending Flaccid Paralysis
Diplopia
Ptosis
Floppy Baby
Constipation
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2 mins
Corynebacterium diphtheriae
Characteristics
Gram-Positive
Bacillus
Exotoxin
ADP Ribosylation of Elongation Factor 2
Beta Prophage
Lysogeny
Tellurite Agar
Chinese Letters
Metachromatic Blue Red Granules
Aniline Stains Deeply Methylene Blue
Signs and Symptoms
Pseudomembranous Pharyngitis
Lymphadenopathy
Myocarditis
Polyneuritis
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3 mins
Staphylococcus aureus Characteristics
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Positive
Beta-Hemolytic
Protein A Virulence Factor
Inhibits Phagocytosis
MRSA
Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
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2 mins
Gonorrhea
Mechanism
Neisseria gonorrhoeae
Assessment
Dysuria
Yellowish-Green Discharge
Increased Urinary Frequency
Women Often Asymptomatic
Interventions
Ceftriaxone (IM)
Chlamydia
Doxycycline
Azithromycin
Considerations
Treat Partners
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2 mins
Neisseria gonorrhoeae Disease
Signs & Symptoms
Dysuria
Pelvic Inflammatory Disease (PID)
Fitz-Hugh-Curtis Syndrome
Neonatal Conjunctivitis
Pharyngitis
Septic Arthritis
Tenosynovitis
Pustules On Hands And Feet
Treatment
Ceftriaxone
Azithromycin
Doxycycline
Considerations
C5-9 Complement Deficiency (Recurrent Infections)
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2 mins
Neisseria gonorrhoeae Characteristics
Characteristics
Gram Negative
Diplococci
Chocolate Agar
Thayer-Martin Media
VPN
Oxidase Positive
Glucose Fermenting
Pilus
Opa Surface Protein
Rapid Antigenic Variation
IgA Protease
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2 mins
Chlamydia
Mechanism
Chlamydia trachomatis
Assessment
May Be Asymptomatic
Dysuria
Epididymitis
Discharge
Dyspareunia
Interventions
Doxycycline
Azithromycin
No Intercourse for 1 Week
Treat Partners
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2 mins
Chlamydia trachomatis
Characteristics
A to C
Trachoma
Follicular Conjunctivitis
Blindness
Africa
L1 to 3
Lymphogranuloma venereum
Buboes
Genital Ulcer
D to K
Urethritis and PID
Neonatal Pneumonia
Staccato Cough
Neonatal Conjunctivitis
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2 mins
Chlamydia Characteristics
Characteristics
Cannot Make ATP
Elementary Body Infects
Intraepithelial
Reticulate Body Replicates
Diagnosis
Cell Wall Lacks Muramic Acid
Giemsa Stain
Inclusion Bodies
Treatment
Doxycycline (Preferred)
Azithromycin
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2 mins
Rheumatic Fever
Pathophysiology
Pharyngeal Infection with Strep Pyogenes (Group A Strep)
Rheumatic Heart Disease
Signs and Symptoms
Aschoff Bodies
Anitschkow's Cells
Early Death Due to Myocarditis
Migratory Polyarthritis
Subcutaneous Nodules
Erythema Marginatum
Chorea
Diagnosis
Elevated ESR
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2 mins
Rheumatic Fever Assessment
Mechanism
Aschoff Bodies
Signs and Symptoms - Major
Carditis
Subcutaneous Nodules
Polyarthritis
Chorea
Erythema Marginatum
Signs and Symptoms - Minor
Fever
Arthralgia
Elevated ESR and C-reactive Protein
Complications
Rheumatic Heart Disease
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2 mins
Rheumatic Fever Interventions
Antibiotics
Prophylactic Treatment
Relieve Joint Pain
Prevent Cardiac Complications
Educate Chorea is Temporary
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1 min
Streptococcus Pyogenes Disease
Pyogenic
Pyogenic
Pyogenic Pharyngitis
Impetigo
Cellulitis
Toxigenic
Toxic Shock-Like Syndrome
Scarlet Fever
Sandpaper Rash
Strawberry Tongue
Immunologic
Immunologic
Rheumatic Fever
Antibodies to M Protein
Acute Glomerulonephritis (Post Streptococcal Glomerulonephritis)
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2 mins
Rocky Mountain Spotted Fever
Rickettsia rickettsii
Dermacentor Wood Tick
Endemic to East Coast
Fever
Headache
Rash Starts on Wrist and Ankle
Rash migrates towards the trunk
Thrombocytopenia
Hyponatremia
Elevated liver enzymes
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59 secs

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