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Pharmacology | Physician Assistant (PA) School Study Aid
Benzodiazepine Intoxication Assessment
- Drowsiness
- Confusion
- Respiratory Depression
- Hypotension
- Coma
- Treatment
- Flumazenil (Romazicon)
2 mins
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Warfarin Antidotes
- Antidotes
- Vitamin K
- Fresh Frozen Plasma
59 secs
Alteplase
- Mechanism
- Tissue Plasminogen Activator
- Indications
- Thrombosis
- Side Effects
- Bleeding
- Contraindications
- Intracranial Hemorrhage
- Internal Hemorrhaging
- Considerations
- Minimize Bleeding
- Monitor for Shock
- Antidote
- Aminocaproic Acid
2 mins
Acetylcholinesterase Inhibitor Poisoning
- DUMBBELSS
- Diarrhea
- Urination
- Miosis
- Bronchospasm
- Bradycardia
- Emesis
- Lacrimation
- Salivation
- Sweating
2 mins
Acetylcholinesterase Inhibitor Antidote
- Antidote
- Atropine
- Pralidoxime
1 min
Acetaminophen Antidote
- Antidote
- N-Acetylcysteine
33 secs
Aspirin Poisoning (Salicylism) Assessment
- Early Symptoms
- Nausea and Vomiting
- Tinnitus
- Confusion
- Hyperventilation
- Respiratory Alkalosis
- Late Symptoms
- Metabolic Acidosis
- Coma
- Hyperthermia
1 min
Atropine
- Indications
- Blocks DUMBBeLSS
- Bradycardia
- Side Effects
- Skin Flushing
- Increased Temperature
- Dry Mouth
- Cycloplegia
- Disorientation
- Mydriasis
1 min
Antimuscarinic Antidote
- Antidote
- Physostigmine Salicylate
44 secs
Amphetamines Intoxication Assessment
- Euphoria
- Insomnia
- Mydriasis
- Diaphoresis
- Hypertension
- Tachycardia
- Paranoia
- Anxiety
- Anorexia
- Seizures
2 mins
Amphetamine Antidote
- Antidote
- Ammonium Chloride (NH4Cl)
- Acidify Urine
34 secs
Beta Blocker Antidote
- Antidote
- Glucagon
29 secs
Arsenic, Gold and Copper Antidotes
- Toxic Metals
- Arsenic
- Gold
- Copper
- Antidotes
- Penicillamine
- Dimercaprol (BAL)
- Succimer
2 mins
Iron Antidote
- Antidote
- DeFEroxamine
23 secs
Opioid Antidote
- Antidote
- Naloxone
29 secs
Tricyclic Antidepressant (TCA) Antidote
- Antidote
- Sodium Bicarbonate (NaHCO3)
27 secs
Lead Antidotes
- Antidotes
- Dimercaprol
- CaEDTA
- Succimer
39 secs
Acute Digoxin Toxicity
- Clinical Symptoms
- Hyperkalemia
- Cholinergic (Nausea, Vomiting, Diarrhea)
- Blurry Yellow Green Vision with Halo of Light
- Arrhythmia
- Bradycardia
- EKG Changes
- Prolonged PR interval
- Decreased QT
- Scooping on EKG
- T Wave Inversion
2 mins
Digoxin Toxicity Treatment
- Activated Charcoal
- Slowly Normalize K+
- Digibind (Anti-Digoxin Fab)
- Magnesium Sulfate
- Lidocaine
- Cardiac Pacing
2 mins
Activated Charcoal (Actidose)
- Mechanism
- Binds to Toxins
- Indications
- Ingested Poison
- Side Effects
- Black Stool
- GI Distress
- Considerations
- Give As Soon As Possible
- Via Mouth or NG Tube
- Gastric Lavage
- Do Not Administer with Antidotes
2 mins
Substance Use Disorder Assessment (Formerly Substance Abuse Assessment)
- Changes in Mood
- Poor Hygiene
- Odd Sleep Patterns
- Frequent Injuries
- Relationship or Job Difficulty
- Poor Performance
- Anorexia OR Weight Loss
- Social Isolation
- Financial Problems
2 mins
Marijuana Intoxication Assessment
- Euphoria
- Slowed Reaction Time
- Conjunctival Injection
- Increased Appetite
- Anxiety
- Social Withdrawal
- Paranoid Delusions
2 mins
Alcohol Use Disorder Assessment (Formerly Alcohol Abuse Assessment)
- Intoxication
- CNS Depression
- Withdrawal
- Wernicke-Korsakoff Syndrome
- Medical Complications
- GI Distress
- Cardiomyopathy
- Pancreatitis
- Cirrhosis
- Immunosuppression
- Sexual Dysfunction
- Considerations
- Screening (Assessments)
3 mins
Alcohol Use Disorder Interventions (Formerly Alcohol Abuse Interventions)
- Withdrawal
- Reduce Environmental Stimuli
- Antianxiety Medications
- Vitamin Supplements
- Seizure Precautions
- Suicide Precautions
- Fever
- Considerations
- Identify Support Systems
- Group Therapy
- Disulfiram
- Naltrexone
2 mins
Cocaine Intoxication Assessment
- Euphoria
- Delusions
- Mydriasis
- Hallucinations
- Agitation
- Hypertension
- Arrhythmias
- Hyperthermia
- Seizures
- Nasal Septum Perforation
2 mins
LSD Intoxication Assessment
- Psychosis
- Perceptual Distortion
- Visual Hallucinations
- Paranoia
- Depersonalization
- Anxiety
- Tachycardia
- Flashbacks
2 mins
Phencyclidine (PCP) Intoxication Assessment
- Violent Behavior
- Motor Issues
- Nystagmus
- Increased Pain Tolerance
- Tachycardia
- Delirium
- Seizures
- Psychosis
2 mins
Opioid Use Disorder and Withdrawal Assessment (Formerly Opioid Abuse and Withdrawal Assessment)
- Abuse Assessment
- Euphoria
- Miosis
- CNS Depression
- Abuse Withdrawal
- Yawning
- Gooseflesh
- Sweating
- Rhinorrhea
- Kicking Movements
- Consideration
- Naloxone
1 min
Naloxone (Narcan)
- Mechanism
- Competitive Opioid Receptor Antagonist
- Indications
- Opioid Induced CNS Depression
- Side Effects
- Severe Nausea and Vomiting
- Excitable State
- Opioid Withdrawal Symptoms
- Considerations
- Repeated Dosing Often Required
1 min
MDMA (Ecstasy) Toxicity: Management
- Airway Management
- Management of Hypertension
- Benzodiazapines
- Nitroprusside
- Activated Charcoal if Within One Hour of Ingestion
- Ice Bath if Hyperthermic
- Cyproheptadine if Serotonin Syndrome
- Fluid Restriction for Hyponatremia
- Hypertonic Saline if Hyponatremia + Altered Mental Status
4 mins
Cyanide Poisoning Diagnosis and Treatment
- Lab Findings
- Lactic Acidosis
- Elevated Venous PO2
- Check Carboxyhemoglobin
- Management
- Sodium Nitrate PLUS Sodium Thiosulfate
- Methemoglobinemia
- OR Hydroxocobalamin (First Line)
4 mins
Cyanide Poisoning: Pathophysiology and Clinical Manifestation
- Pathophysiology
- Inhibits Complex IV of Oxidative Phosphorylation
- Forces Cells Into Anaerobic Metabolism
- Presentation
- Exposure to Fire Fumes
- Industrial Exposure
- Headache and Confusion
- Arrhythmias
- "Cherry Red" Skin
- Almond Breath/Taste
- Acute Renal Failure
4 mins
MDMA (Ecstasy) Toxicity: Mechanism and Clinical Findings
- Mechanism
- Sympathomimetic
- Increases Release and Blocks Reuptake of Catecholamines
- Clinical Presentation
- Euphoria
- Increased Alertness
- Extreme Hyponatremia Leading to Altered Mental Status
- Acute Liver Injury
- Serotonin Syndrome
- Rhabdomyolysis
- Hypertensive Urgency/Emergency
- Arrhythmia
5 mins
Substance Use Disorder
- Diagnostic Criteria
- 2 or More Symptoms For 1 year
- Tolerance
- Withdrawal Symptoms
- Cravings
- Using More Than Intended
- Inability to Cut Down
- Time-Consuming Substance Acquisition
- Impaired Functioning at Work
- Reduced Recreational Activities
- Dangerous Activities
- Continued Use
2 mins
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