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Pharmacology | Physician Assistant (PA) School Study Aid
Antipsychotics Overview
- Generations
- Typical
- Atypical
- Mechanism
- Blocks D2 Receptor
- 2nd Generation Blocks the 5-HT 2 Receptor
- Indications
- Psychosis
- Delirium
- Bipolar Disorder
- Tourette’s Syndrome
- Side Effects
- Hyperprolactinemia
- Extrapyramidal Symptoms
- Tardive Dyskinesia
- Neuroleptic Malignant Syndrome
4 mins
Low Potency Antipsychotic Drugs
- Drugs
- Chlorpromazine
- Corneal Deposits
- Thioridazine
- Retinal Deposits
- Shared Side Effects
- Alpha1 Antagonist Effects
- Anticholinergic Effects
- Antihistamine Effects
2 mins
High Potency Antipsychotic Drugs
- High Potency Drugs
- Fluphenazine
- Trifluoperazine
- Haloperidol
- Pimozide
- Side Effects
- Extrapyramidal Symptoms
- Short Term
- Dystonia
- Restlessness (Akathisia)
- Torticollis
- Long Term
- Tardive Dyskinesia
- Parkinson's-Like Symptoms
- Neuroleptic Malignant Syndrome
3 mins
Atypical Antipsychotics
- Indications
- Schizophrenia
- Mechanism of Action
- Unknown Mechanism
- Side Effects
- Seizures
- Prolonged QT Interval
- Agranulocytosis
- Weight Gain
- Fewer Extrapyramidal Side Effects
- Fewer Anticholinergic Side Effects
2 mins
Haloperidol (Haldol)
- Mechanism
- High Potency Antipsychotic
- Indications
- Migraine
- Schizophrenia
- Side Effects
- Extrapyramidal Symptoms
- Weight Gain
- QT Prolongation
- Restlessness
- Considerations
- Caution in Seizure Patients
- Neuroleptic Malignant Syndrome
2 mins
Chlorpromazine (Thorazine)
- Mechanism
- Low Potency Antipsychotic
- Indications
- Schizophrenia
- Hiccups
- Side Effects
- Sedation
- Weight Gain
- Orthostatic Hypotension
- Anticholinergic Effects
- QT Prolongation
- Neuroendocrine Effects
- Caution in Seizure Patients
- Corneal Deposits
2 mins
Clozapine (Clozaril)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Levodopa-Induced Psychosis
- Side Effects
- Weight Gain
- Hypersalivation (Sialorrhea)
- Myocarditis
- Agranulocytosis
- Sedation
- Orthostatic Hypotension
- Constipation (Risk of Bowel Ileus)
- Considerations
- Weekly Lab Tests
2 mins
Risperidone (Risperdal)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Side Effects
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Considerations
- Intramuscular Long Acting (Depot) Form
2 mins
Aripiprazole (Abilify)
- Mechanism
- 2nd Generation Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Disorder
- Depression
- Side Effects
- Headache
- Dizziness
- Nausea and Vomiting
- Insomnia
- Anxiety
- Considerations
- Low Risk of Extrapyramidal Symptoms
- Lowest Risk of Weight Gain
2 mins
Lithium
- Indications
- Bipolar Disorder
- Mechanism of Action
- Mood Stabilizer
- Unknown Mechanism
- Side Effects
- Nephrogenic Diabetes Insipidus
- Hypothyroidism
- Movement (Tremor)
- Heart Block
- Contraindication
- Pregnancy (Ebstein's Anomaly)
1 min
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