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Pharmacology | Physician Assistant (PA) School Study Aid
Nondepolarizing Neuromuscular Blocking Drugs
- Names Include "Cur"
- Competitive Antagonists
- Acetylcholine Competition
- Reversal of Blockade
- Neostigmine, Edrophonium
1 min
Succinylcholine
- Indications
- Inducing Paralysis
- Mechanism of Action
- Neuromuscular Blocking Drugs
- Motor Nicotinic Receptor
- ACh Receptor Agonist
- Depolarization
- Phases of Action
- Phase I (Paralysis Non-reversible)
- Phase II (Paralysis Reversible)
- Neostigmine (Reversal Agent)
2 mins
Cyclobenzaprine (Flexeril)
- Mechanism
- Centrally-Acting Muscle Relaxer
- Act on Alpha and Gamma Motor Neurons
- Related to Tricyclic Antidepressants (TCAs)
- Uses
- Muscle Spasms
- Back Pain
- Side Effects/Interactions
- MAO Inhibitors
- Serotonin Syndrome
- Drowsiness
- Arrhythmia
3 mins
Baclofen
- Mechanism
- GABA-B Receptor Agonist
- Spinal Cord
- Indications
- Spasticity
- Dystonia
- Multiple Sclerosis
- Side Effects
- CNS Depression
- Nausea
- Considerations
- Taper Gradually
1 min
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